Skin science article
Isntree C-Niacin Toning Ampoule Versus Beauty of Joseon Light On Serum : Centella + Vita C
Isntree C-Niacin Toning Ampoule Versus Beauty of Joseon Light On Serum : Centella + Vita C This brightening ampoule is formulated around Hippophae Rhamnoides Fruit Extract and Niacinamide to brighten dull-looking skin and calm redness. This brightening serum i
Isntree C-Niacin Toning Ampoule Versus Beauty of Joseon Light On Serum : Centella + Vita C
This brightening ampoule is formulated around Hippophae Rhamnoides Fruit Extract and Niacinamide to brighten dull-looking skin and calm redness.
This brightening serum is formulated around Centella Asiatica Extract and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Hippophae Rhamnoides Fruit Extract
Butylene Glycol
Pentylene Glycol
Glycerin
Betaine
Water
Niacinamide
Propanediol
Aloe Barbadensis Leaf Extract
Melia Azadirachta Flower Extract
Melia Azadirachta Leaf Extract
Cucurbita Pepo Fruit Extract
Physalis Alkekengi Fruit Extract
Sodium Hyaluronate
Dipotassium Glycyrrhizate
Ocimum Sanctum Leaf Extract
Beta-Glucan
Curcuma Longa Root Extract
Corallina Officinalis Extract
Brassica Oleracea Italica Extract
Coccinia Indica Fruit Extract
Moringa Oleifera Seed Oil
Boswellia Serrata Resin Extract
Bioflavonoids
Panthenol
Allantoin
Sodium Polyacrylate
Ammonium Acryloyldimethyltaurate/Vp Copolymer
3-O-Ethyl Ascorbic Acid
Ethyl Hexanediol
Polysorbate 80
1,2-Hexanediol
Hippophae Rhamnoides Fruit Extract, Butylene Glycol, Pentylene Glycol, Glycerin, Betaine, Water, Niacinamide, Propanediol, Aloe Barbadensis Leaf Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Cucurbita Pepo Fruit Extract, Physalis Alkekengi Fruit Extract, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Ocimum Sanctum Leaf Extract, Beta-Glucan, Curcuma Longa Root Extract, Corallina Officinalis Extract, Brassica Oleracea Italica Extract, Coccinia Indica Fruit Extract, Moringa Oleifera Seed Oil, Boswellia Serrata Resin Extract, Bioflavonoids, Panthenol, Allantoin, Sodium Polyacrylate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, 3-O-Ethyl Ascorbic Acid, Ethyl Hexanediol, Polysorbate 80, 1,2-Hexanediol
Centella Asiatica Extract
Dicaprylyl Carbonate
Methyl Trimethicone
Cetyl Ethylhexanoate
Laminaria Japonica Extract
Eclipta Prostrata Leaf Extract
Phellodendron Amurense Bark Extract
Citrus Unshiu Peel Extract
Brassica Oleracea Acephala Leaf Extract
Hydrolyzed Gardenia Florida Extract
Hydrogenated Lecithin
Cetearyl Alcohol
Dimethicone/Vinyl Dimethicone Crosspolymer
Silica
Bisabolol
Potassium Cetyl Phosphate
Hydrolyzed Jojoba Esters
Cetearyl Olivate
Sorbitan Olivate
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer
Xanthan Gum
Polyglyceryl-10 Myristate
Adenosine
Fructooligosaccharides
Sorbitan Isostearate
Hydrolyzed Hyaluronic Acid
Maltodextrin
Arginine
Carbomer
Ascorbic Acid Polypeptide
Hydroxyacetophenone
Ethylhexylglycerin
Centella Asiatica Extract, 3-O-Ethyl Ascorbic Acid, Glycerin, Propanediol, Betaine, Dicaprylyl Carbonate, Methyl Trimethicone, Cetyl Ethylhexanoate, Panthenol, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Phellodendron Amurense Bark Extract, Citrus Unshiu Peel Extract, Brassica Oleracea Acephala Leaf Extract, Hydrolyzed Gardenia Florida Extract, Hydrogenated Lecithin, Cetearyl Alcohol, Water, Dimethicone/Vinyl Dimethicone Crosspolymer, Silica, Bisabolol, Potassium Cetyl Phosphate, Hydrolyzed Jojoba Esters, Cetearyl Olivate, Sorbitan Olivate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Xanthan Gum, Polyglyceryl-10 Myristate, Adenosine, Fructooligosaccharides, Beta-Glucan, Butylene Glycol, Sorbitan Isostearate, Hydrolyzed Hyaluronic Acid, Maltodextrin, Arginine, Carbomer, Ascorbic Acid Polypeptide, 1,2-Hexanediol, Hydroxyacetophenone, Ethylhexylglycerin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
3-O-Ethyl Ascorbic Acid is one of the most popular "stable" vitamin C derivatives in skincare.
Plain ascorbic acid is fantastic but notoriously fragile; it browns, oxidizes, and loses potency fast. So attaching an ethyl group to the third carbon of the molecule gives it some cool perks:
In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen.
The evidence is reasonably solid for a cosmetic ingredient; Liao and colleagues (2018) showed it's significantly more stable than ascorbic acid while still being effective.
A 2021 study by Zerbinati and colleagues tested a serum with 30% 3-O-ethyl-l-ascorbic acid and 1% lactic acid significantly increased collagen production, reduced UVB-induced DNA damage, and decreased melanin on a reconstructed pigmented skin model.
Typical real world usage sits around 0.5-5% (and 1-2% is common for daily serums).
Amounts up to 30% have been shown to be non-irritating on human skin samples, but two isolated cases reported allergic contact dermatitis so a patch test is sensible if you have reactive skin.
Beta-Glucan is a soluble polysaccharide (a chain of glucose sugars) sourced from the cells walls of oats, baker's yeast, mushrooms, and seaweed.
It's a rare ingredient that pulls double-duty as a heavy-duty hydrator and skin-soothing repair agent.
On the surface, it acts as a humectant that holds water in place and reduces moisture loss for a plumper, smoother feel, while its anti-inflammatory and antioxidant properties make it a great pick for calming redness or sensitive skin
The more interesting story is underneath:
Despite its large molecular size, oat beta-glucan has been shown to penetrate the epidermis and reach the dermis by slipping between skin cells. Here, it interacts with fibroblasts and macrophages to nudge collagen synthesis and support wound repair.
A small 2005 split-face clinical study of 27 subjects found topical beta-glucan produced measurable reductions in wrinkle depth, height, and roughness after 8 weeks of use.
It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive.
This ingredient gets along with pretty much everything and is typically used around 0.1-1%.
Fungal acne: This ingredient is not a food source for the Malassezia yeast because it is a glucose polysaccharide with no fatty acid or ester component.
Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!