Skin science article
Isntree Onion Newpair Gel Cream Versus Beauty of Joseon Dynasty Cream (Old Formulation)
Isntree Onion Newpair Gel Cream Versus Beauty of Joseon Dynasty Cream (Old Formulation) This calming day moisturizer is formulated around Allium Cepa Bulb Extract and Niacinamide to calm redness and fade the look of dark spots. This barrier-repair moisturizer
Isntree Onion Newpair Gel Cream Versus Beauty of Joseon Dynasty Cream (Old Formulation)
This calming day moisturizer is formulated around Allium Cepa Bulb Extract and Niacinamide to calm redness and fade the look of dark spots.
This barrier-repair moisturizer is formulated around Niacinamide and Adenosine to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Allium Cepa Bulb Extract
Propanediol
Glycerin
Water
Butylene Glycol
Caprylic/Capric Triglyceride
Niacinamide
1,2-Hexanediol
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Cetearyl Alcohol
Vinyldimethicone
Carbomer
Cetearyl Olivate
Sorbitol
Sorbitan Olivate
Biosaccharide Gum-1
Sodium Polyacryloyldimethyl Taurate
Sodium Ascorbyl Phosphate
Tromethamine
Melia Azadirachta Leaf Extract
Melia Azadirachta Flower Extract
Sorbitan Isostearate
Hydrogenated Polydecene
Ethylhexylglycerin
Citric Acid
Adenosine
Hydroxyethylcellulose
Coccinia Indica Fruit Extract
Disodium EDTA
Betaine
Sodium Citrate
Tranexamic Acid
Allantoin
Houttuynia Cordata Extract
Panthenol
Solanum Melongena Fruit Extract
Trideceth-10
Hyaluronic Acid
Hydrolyzed Hyaluronic Acid
Sodium Hyaluronate
Corallina Officinalis Extract
Ocimum Sanctum Leaf Extract
Curcuma Longa Root Extract
Sodium Heparin
Allium Cepa Bulb Extract, Propanediol, Glycerin, Water, Butylene Glycol, Caprylic/Capric Triglyceride, Niacinamide, 1,2-Hexanediol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Vinyldimethicone, Carbomer, Cetearyl Olivate, Sorbitol, Sorbitan Olivate, Biosaccharide Gum-1, Sodium Polyacryloyldimethyl Taurate, Sodium Ascorbyl Phosphate, Tromethamine, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Sorbitan Isostearate, Hydrogenated Polydecene, Ethylhexylglycerin, Citric Acid, Adenosine, Hydroxyethylcellulose, Coccinia Indica Fruit Extract, Disodium EDTA, Betaine, Sodium Citrate, Tranexamic Acid, Allantoin, Houttuynia Cordata Extract, Panthenol, Solanum Melongena Fruit Extract, Trideceth-10, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Corallina Officinalis Extract, Ocimum Sanctum Leaf Extract, Curcuma Longa Root Extract, Sodium Heparin
Dipentaerythrityl Hexa C5-9 Acid Esters
Xanthan Gum
Cyclopentasiloxane
Cyclohexasiloxane
Polyacrylate-13
Polyisobutene
Polysorbate 20
Hydrogenated Lecithin
C14-28 Alkyl Acid
Stearyl Alcohol
Behenyl Alcohol
Dimethicone/Vinyl Dimethicone Crosspolymer
Dimethicone
Glyceryl Stearate Se
Polyglyceryl-3 Methylglucose Distearate
Cetyl PEG/PPG-10/1 Dimethicone
Stearic Acid
Tocopheryl Acetate
Sodium Polyacrylate
Olea Europaea Fruit Oil
Helianthus Annuus Seed Oil
Centella Asiatica Extract
Hippophae Rhamnoides Oil
Argania Spinosa Kernel Oil
Butyrospermum Parkii Butter
Ceramide NP
Trehalose
Calendula Officinalis Flower Extract
Caprylhydroxamic Acid
Raphanus Sativus Leaf Extract
Oryza Sativa Bran Extract
Cucurbitaceae Extract
Orchid Extract
Honey Extract
Panax Ginseng Root Extract
Carthamus Tinctorius Seed Oil
Phytosphingosine
Ceteareth-20
Glyceryl Citrate/Lactate/Linoleate/Oleate
Parfum
Water, Glycerin, Butylene Glycol, Niacinamide, Dipentaerythrityl Hexa C5-9 Acid Esters, Sodium Hyaluronate, Xanthan Gum, Cyclopentasiloxane, Cyclohexasiloxane, Polyacrylate-13, Polyisobutene, Polysorbate 20, Hydrogenated Lecithin, C14-28 Alkyl Acid, Stearyl Alcohol, Behenyl Alcohol, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethicone, Adenosine, Glyceryl Stearate Se, Cetearyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Cetyl PEG/PPG-10/1 Dimethicone, Stearic Acid, Tocopheryl Acetate, Sodium Polyacrylate, Olea Europaea Fruit Oil, Helianthus Annuus Seed Oil, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Argania Spinosa Kernel Oil, Butyrospermum Parkii Butter, Ceramide NP, Trehalose, Calendula Officinalis Flower Extract, Caprylhydroxamic Acid, 1,2-Hexanediol, Raphanus Sativus Leaf Extract, Oryza Sativa Bran Extract, Cucurbitaceae Extract, Orchid Extract, Honey Extract, Panax Ginseng Root Extract, Carthamus Tinctorius Seed Oil, Phytosphingosine, Ceteareth-20, Glyceryl Citrate/Lactate/Linoleate/Oleate, Parfum
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!