Isntree Ultra-Low Molecular Hyaluronic Acid Serum Versus COSRX The 6 Peptide Skin Booster Serum

Isntree Ultra-Low Molecular Hyaluronic Acid Serum Versus COSRX The 6 Peptide Skin Booster Serum

This hydrating serum is formulated around Panthenol and Hydrolyzed Hyaluronic Acid to hydrate skin and strengthen the skin barrier.

This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Sea Water

Water

Methylpropanediol

Glycerin

Butylene Glycol

1,2-Hexanediol

Betaine

Pentylene Glycol

Carbomer

Caprylyl Glycol

Allantoin

Tromethamine

Ethylhexylglycerin

Xanthan Gum

Panthenol

Malachite Extract

Hydrolyzed Hyaluronic Acid

Disodium EDTA

Glyceryl Acrylate/Acrylic Acid Copolymer

Glyceryl Glucoside

Sodium Hyaluronate

Potassium Hyaluronate

Hyaluronic Acid

Hydrolyzed Sodium Hyaluronate

Sodium Acetylated Hyaluronate

Hydroxypropyltrimonium Hyaluronate

Sodium Hyaluronate Crosspolymer

Dimethylsilanol Hyaluronate

Hydrolyzed Calcium Hyaluronate

Sodium Sulfated Hyaluronate

Madecassoside

Beta-Glucan

Sodium Stearoyl Hyaluronate

Sodium Oleoyl Hyaluronate

Sea Water, Water, Methylpropanediol, Glycerin, Butylene Glycol, 1,2-Hexanediol, Betaine, Pentylene Glycol, Carbomer, Caprylyl Glycol, Allantoin, Tromethamine, Ethylhexylglycerin, Xanthan Gum, Panthenol, Malachite Extract, Hydrolyzed Hyaluronic Acid, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Glyceryl Glucoside, Sodium Hyaluronate, Potassium Hyaluronate, Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Dimethylsilanol Hyaluronate, Hydrolyzed Calcium Hyaluronate, Sodium Sulfated Hyaluronate, Madecassoside, Beta-Glucan, Sodium Stearoyl Hyaluronate, Sodium Oleoyl Hyaluronate

Dipropylene Glycol

Niacinamide

Acetyl Hexapeptide-8

Copper Tripeptide-1

Sh-Polypeptide-121

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Oligopeptide-68

Palmitoyl Tripeptide-8

Acetyl Glucosamine

Serine

Alanine

Glycine

Threonine

Arginine

Proline

Sodium PCA

Sodium Lactate

PCA

Glutamic Acid

Lysine Hcl

Tocopherol

Dextran

Glycine Soja Oil

Hydrogenated Lecithin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Polyacrylate Crosspolymer-6

Adenosine

Polyquaternium-51

Citric Acid

T-Butyl Alcohol

Potassium Sorbate

Sodium Oleate

Water, Dipropylene Glycol, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Niacinamide, Acetyl Hexapeptide-8, Copper Tripeptide-1, Sh-Polypeptide-121, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Oligopeptide-68, Palmitoyl Tripeptide-8, Allantoin, Sodium Hyaluronate, Acetyl Glucosamine, Serine, Alanine, Glycine, Threonine, Arginine, Proline, Betaine, Sodium PCA, Sodium Lactate, PCA, Glutamic Acid, Lysine Hcl, Tocopherol, Dextran, Glycine Soja Oil, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyacrylate Crosspolymer-6, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Adenosine, Polyquaternium-51, Disodium EDTA, Citric Acid, Caprylyl Glycol, T-Butyl Alcohol, Potassium Sorbate, Sodium Oleate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.

Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.

Some studies suggest betaine may support making skin tone more even.

Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.

Betaine is also known as trimethylglycine.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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