Skin science article
iUNIK Black Snail Restore Serum Versus Missha Time Revolution Night Repair Probio Ampoule
iUNIK Black Snail Restore Serum Versus Missha Time Revolution Night Repair Probio Ampoule This barrier-repair serum is formulated around Centella Asiatica Leaf Water and Niacinamide to strengthen the skin barrier and calm redness. This barrier-repair ampoule i
iUNIK Black Snail Restore Serum Versus Missha Time Revolution Night Repair Probio Ampoule
This barrier-repair serum is formulated around Centella Asiatica Leaf Water and Niacinamide to strengthen the skin barrier and calm redness.
This barrier-repair ampoule is formulated around Bifida Ferment Lysate and Niacinamide to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Centella Asiatica Leaf Water
Glycerin
1,2-Hexanediol
Butylene Glycol
Niacinamide
Glycereth-26
Snail Extract
Scutellaria Baicalensis Root Extract
Polygonum Cuspidatum Root Extract
Oryza Sativa Extract
Coffea Arabica Seed Extract
Laminaria Japonica Extract
Sesamum Indicum Seed Extract
Solanum Melongena Fruit Extract
Dipotassium Glycyrrhizate
Camellia Sinensis Leaf Extract
Cynanchum Atratum Extract
Chamomilla Recutita Flower Extract
Rosmarinus Officinalis Leaf Extract
Centella Asiatica Extract
Arginine
Carbomer
Adenosine
Ethylhexylglycerin
Sodium Polyacrylate
Xanthan Gum
Sodium Hyaluronate
Pentylene Glycol
Caprylyl Glycol
Water, Centella Asiatica Leaf Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Niacinamide, Glycereth-26, Snail Extract, Scutellaria Baicalensis Root Extract, Polygonum Cuspidatum Root Extract, Oryza Sativa Extract, Coffea Arabica Seed Extract, Laminaria Japonica Extract, Sesamum Indicum Seed Extract, Solanum Melongena Fruit Extract, Dipotassium Glycyrrhizate, Camellia Sinensis Leaf Extract, Cynanchum Atratum Extract, Chamomilla Recutita Flower Extract, Rosmarinus Officinalis Leaf Extract, Centella Asiatica Extract, Arginine, Carbomer, Adenosine, Ethylhexylglycerin, Sodium Polyacrylate, Xanthan Gum, Sodium Hyaluronate, Pentylene Glycol, Caprylyl Glycol
Bifida Ferment Lysate
Sorbus Commixta Extract
Juniperus Chinensis Xylem Extract
Bis-PEG-18 Methyl Ether Dimethyl Silane
Leuconostoc Ferment Filtrate
Betaine
Grifola Frondosa/Ophioglossum Vulgatum Extract Ferment Filtrate
Lactobacillus/Rice Ferment Filtrate
Portulaca Oleracea Extract
Anthemis Nobilis Flower Extract
Hydrolyzed Rice Extract
Sea Water
Carthamus Tinctorius Oleosomes
Hydrolyzed Extensin
Daucus Carota Sativa Root Extract
Vaccinium Angustifolium Fruit Extract
Beta Vulgaris Root Extract
Aronia Arbutifolia Extract
Brassica Oleracea Capitata Leaf Extract
Echium Plantagineum Seed Oil
Ascorbyl Tetraisopalmitate
Lactobacillus Ferment
Lactococcus Ferment Lysate
Manilkara Multinervis Leaf Extract
Theobroma Cacao Seed Extract
Cassia Alata Leaf Extract
Laminaria Digitata Extract
Saccharomyces Ferment Filtrate
Lactobacillus/Soybean Ferment Extract
Saccharomyces/Viscum Album Ferment Extract
Yeast Ferment Extract
Pogostemon Cablin Leaf Oil
Pseudoalteromonas Ferment Extract
Cardiospermum Halicacabum Flower/Leaf/Vine Extract
Helianthus Annuus Seed Oil Unsaponifiables
Alpha-Glucan Oligosaccharide
Limnanthes Alba Seed Oil
Hydrolyzed Wheat Protein
Beta-Sitosterol
Panthenol
Hydrolyzed Soy Protein
Ubiquinone
Macadamia Ternifolia Seed Oil
Retinol
Cucumis Melo Fruit Extract
Biotin
Brassica Campestris Sterols
Sodium Ascorbyl Phosphate
Amaranthus Caudatus Seed Extract
Tripeptide-10 Citrulline
Acetyl Hexapeptide-8
Copper Tripeptide-1
Tripeptide-1
Acacia Arabica Stem Bark Extract
Cholesterol
Glyceryl Linolenate
Glyceryl Linoleate
Glyceryl Arachidonate
Cyclopentasiloxane
Ethyl Hexanediol
Dimethicone
PEG-11 Methyl Ether Dimethicone
PEG-40 Hydrogenated Castor Oil
PPG-26-Buteth-26
Polysorbate 20
Glyceryl Caprylate
Triethanolamine
Dimethicone/Vinyl Dimethicone Crosspolymer
Octyldodecanol
Dipropylene Glycol
Cyclomethicone
Hydrogenated Lecithin
Disodium EDTA
Dextrin
Lauryl Methacrylate/Glycol Dimethacrylate Crosspolymer
Glyceryl Polyacrylate
Dimethiconol
Propylene Glycol
Ceteth-24
Choleth-24
Hydroxypropyltrimonium Maltodextrin Crosspolymer
Cetyl Phosphate
Caprylic/Capric Triglyceride
Lecithin
PEG-5 Rapeseed Sterol
BHT
Ceteth-3
Ceteth-5
Silica
Tocopheryl Acetate
Phenoxyethanol
Water, Bifida Ferment Lysate, Glycereth-26, Sorbus Commixta Extract, Juniperus Chinensis Xylem Extract, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Glycerin, Niacinamide, Leuconostoc Ferment Filtrate, Betaine, Grifola Frondosa/Ophioglossum Vulgatum Extract Ferment Filtrate, Lactobacillus/Rice Ferment Filtrate, Portulaca Oleracea Extract, Sodium Hyaluronate, Anthemis Nobilis Flower Extract, Hydrolyzed Rice Extract, Sea Water, Carthamus Tinctorius Oleosomes, Hydrolyzed Extensin, Adenosine, Daucus Carota Sativa Root Extract, Vaccinium Angustifolium Fruit Extract, Beta Vulgaris Root Extract, Aronia Arbutifolia Extract, Brassica Oleracea Capitata Leaf Extract, Echium Plantagineum Seed Oil, Ascorbyl Tetraisopalmitate, Lactobacillus Ferment, Lactococcus Ferment Lysate, Manilkara Multinervis Leaf Extract, Theobroma Cacao Seed Extract, Cassia Alata Leaf Extract, Laminaria Digitata Extract, Saccharomyces Ferment Filtrate, Lactobacillus/Soybean Ferment Extract, Saccharomyces/Viscum Album Ferment Extract, Yeast Ferment Extract, Pogostemon Cablin Leaf Oil, Pseudoalteromonas Ferment Extract, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Helianthus Annuus Seed Oil Unsaponifiables, Alpha-Glucan Oligosaccharide, Limnanthes Alba Seed Oil, Hydrolyzed Wheat Protein, Beta-Sitosterol, Panthenol, Hydrolyzed Soy Protein, Ubiquinone, Macadamia Ternifolia Seed Oil, Retinol, Cucumis Melo Fruit Extract, Biotin, Brassica Campestris Sterols, Sodium Ascorbyl Phosphate, Amaranthus Caudatus Seed Extract, Tripeptide-10 Citrulline, Acetyl Hexapeptide-8, Copper Tripeptide-1, Tripeptide-1, Acacia Arabica Stem Bark Extract, Cholesterol, Glyceryl Linolenate, Glyceryl Linoleate, Glyceryl Arachidonate, Cyclopentasiloxane, Ethyl Hexanediol, Dimethicone, PEG-11 Methyl Ether Dimethicone, PEG-40 Hydrogenated Castor Oil, PPG-26-Buteth-26, Polysorbate 20, Carbomer, Glyceryl Caprylate, Triethanolamine, Dimethicone/Vinyl Dimethicone Crosspolymer, Octyldodecanol, Xanthan Gum, Dipropylene Glycol, Cyclomethicone, Hydrogenated Lecithin, Disodium EDTA, Dextrin, Lauryl Methacrylate/Glycol Dimethacrylate Crosspolymer, Glyceryl Polyacrylate, Dimethiconol, Propylene Glycol, Ceteth-24, Choleth-24, Hydroxypropyltrimonium Maltodextrin Crosspolymer, Cetyl Phosphate, Caprylic/Capric Triglyceride, Lecithin, PEG-5 Rapeseed Sterol, BHT, Ceteth-3, Ceteth-5, Silica, Tocopheryl Acetate, Phenoxyethanol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
It is a humectant and helps add texture to products. It can make your product thicker.
As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.