Juice Beauty Signal Peptides Firming Serum Versus ma:nyo Bifida Biome Complex Ampoule

Juice Beauty Signal Peptides Firming Serum Versus ma:nyo Bifida Biome Complex Ampoule

This anti-aging serum is formulated around Aloe Barbadensis Leaf Juice and Squalane to soften the look of wrinkles and hydrate skin.

This barrier-repair ampoule is formulated around Bifida Ferment Lysate and Niacinamide to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Aloe Barbadensis Leaf Juice

Glycerin

Coconut Alkanes

Caprylic/Capric Triglyceride

Squalane

Polyglyceryl-10 Mono/Dioleate

Dicaprylyl Maleate

Cetyl Alcohol

Olea Europaea Fruit Oil

Butyrospermum Parkii Butter

Hydrolyzed Rice Bran Extract

Phosphatidylglycerol

Polyglyceryl-3 Oleate

Glycine Soja Sterols

Piper Angustifolium Extract

Linum Usitatissimum Seed Extract

Helianthus Annuus Seed Oil

Hyaluronic Acid

Tocopherol

Glyceryl Cocoate

Coco-Caprylate

Cetearyl Olivate

Sorbitan Olivate

Cetyl Hydroxyethylcellulose

Xanthan Gum

Caprylyl Glycol

Squalene

Gluconolactone

Leuconostoc/Radish Root Ferment Filtrate

Sodium Benzoate

Triethyl Citrate

Citrus Aurantium Bergamia Fruit Oil

Citrus Aurantium Dulcis Oil

Aloe Barbadensis Leaf Juice, Glycerin, Coconut Alkanes, Caprylic/Capric Triglyceride, Squalane, Polyglyceryl-10 Mono/Dioleate, Dicaprylyl Maleate, Cetyl Alcohol, Olea Europaea Fruit Oil, Butyrospermum Parkii Butter, Hydrolyzed Rice Bran Extract, Phosphatidylglycerol, Polyglyceryl-3 Oleate, Glycine Soja Sterols, Piper Angustifolium Extract, Linum Usitatissimum Seed Extract, Helianthus Annuus Seed Oil, Hyaluronic Acid, Tocopherol, Glyceryl Cocoate, Coco-Caprylate, Cetearyl Olivate, Sorbitan Olivate, Cetyl Hydroxyethylcellulose, Xanthan Gum, Caprylyl Glycol, Squalene, Gluconolactone, Leuconostoc/Radish Root Ferment Filtrate, Sodium Benzoate, Triethyl Citrate, Citrus Aurantium Bergamia Fruit Oil, Citrus Aurantium Dulcis Oil

Water

Butylene Glycol

Bifida Ferment Lysate

Niacinamide

1,2-Hexanediol

Pentylene Glycol

Polyglyceryl-10 Laurate

Bifida Ferment Filtrate

Lactobacillus Ferment Lysate

Lactococcus Ferment Lysate

Saccharomyces Ferment Filtrate

Carbomer

Hydrogenated Lecithin

Tromethamine

Propanediol

Ethylhexylglycerin

Adenosine

Dextrin

Theobroma Cacao Seed Extract

Sodium Hyaluronate

Sodium Phytate

Lactobacillus/Pumpkin Fruit Ferment Filtrate

Cutibacterium Granulosum Ferment Extract Filtrate

Caffeine

Leontopodium Alpinum Callus Culture Extract

Physalis Alkekengi Calyx Extract

Hydrolyzed Algin

Aureobasidium Pullulans Ferment

Epigallocatechin Gallate

Benzyl Glycol

Hydrolyzed Glycosaminoglycans

Asiatic Acid

Asiaticoside

Madecassic Acid

Hydroxypropyltrimonium Hyaluronate

Sodium Hyaluronate Crosspolymer

Hydrolyzed Hyaluronic Acid

Sodium Acetylated Hyaluronate

Copper Tripeptide-1

Hydrolyzed Sodium Hyaluronate

Acetyl Hexapeptide-8

Potassium Hyaluronate

Water, Butylene Glycol, Bifida Ferment Lysate, Glycerin, Niacinamide, 1,2-Hexanediol, Pentylene Glycol, Squalane, Polyglyceryl-10 Laurate, Bifida Ferment Filtrate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Saccharomyces Ferment Filtrate, Carbomer, Hydrogenated Lecithin, Tromethamine, Xanthan Gum, Propanediol, Ethylhexylglycerin, Adenosine, Dextrin, Theobroma Cacao Seed Extract, Sodium Hyaluronate, Sodium Phytate, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Cutibacterium Granulosum Ferment Extract Filtrate, Caffeine, Leontopodium Alpinum Callus Culture Extract, Physalis Alkekengi Calyx Extract, Hydrolyzed Algin, Aureobasidium Pullulans Ferment, Epigallocatechin Gallate, Benzyl Glycol, Hydrolyzed Glycosaminoglycans, Asiatic Acid, Asiaticoside, Madecassic Acid, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hyaluronic Acid, Copper Tripeptide-1, Hydrolyzed Sodium Hyaluronate, Acetyl Hexapeptide-8, Potassium Hyaluronate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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