Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Kiehl's Creamy Eye Treatment with Avocado Versus Dr. Lara Devgan Peptide Eye Cream

Kiehl's Creamy Eye Treatment with Avocado Versus Dr. Lara Devgan Peptide Eye Cream This barrier-repair eye moisturizer is formulated around Butyrospermum Parkii Butter and Persea Gratissima Oil to strengthen the skin barrier and hydrate skin. This anti-aging e

Kiehl's Creamy Eye Treatment with Avocado Versus Dr. Lara Devgan Peptide Eye Cream

This barrier-repair eye moisturizer is formulated around Butyrospermum Parkii Butter and Persea Gratissima Oil to strengthen the skin barrier and hydrate skin.

This anti-aging eye moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butyrospermum Parkii Butter

Butylene Glycol

Tridecyl Stearate

PEG-30 Dipolyhydroxystearate

Isodecyl Salicylate

Tridecyl Trimellitate

Persea Gratissima Oil

Isocetyl Stearoyl Stearate

Propylene Glycol

Dipentaerythrityl Hexacaprylate/Hexacaprate

Sorbitan Sesquioleate

Magnesium Sulfate

Hydrogenated Castor Oil

Sodium PCA

Phenoxyethanol

Chlorphenesin

Hydrogenated Jojoba Oil

P-Anisic Acid

Tocopheryl Acetate

Isopropyl Palmitate

Disodium EDTA

Copper PCA

Helianthus Annuus Seed Oil

CI 40800

Citric Acid

Water, Butyrospermum Parkii Butter, Butylene Glycol, Tridecyl Stearate, PEG-30 Dipolyhydroxystearate, Isodecyl Salicylate, Tridecyl Trimellitate, Persea Gratissima Oil, Isocetyl Stearoyl Stearate, Propylene Glycol, Dipentaerythrityl Hexacaprylate/Hexacaprate, Sorbitan Sesquioleate, Magnesium Sulfate, Hydrogenated Castor Oil, Sodium PCA, Phenoxyethanol, Chlorphenesin, Hydrogenated Jojoba Oil, P-Anisic Acid, Tocopheryl Acetate, Isopropyl Palmitate, Disodium EDTA, Copper PCA, Helianthus Annuus Seed Oil, CI 40800, Citric Acid

Glycerin

Dimethicone

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Steareth-20

Chrysin

N-Hydroxysuccinimide

Carbomer

Polysorbate 20

Glycol Distearate

Glyceryl Stearate

PEG-100 Stearate

Stearic Acid

Stearyl Alcohol

Phytonadione Epoxide

Vitis Vinifera Seed Oil

Allantoin

Titanium Dioxide

Tetrasodium EDTA

Triethanolamine

Ethylhexylglycerin

Water, Helianthus Annuus Seed Oil, Glycerin, Dimethicone, Isopropyl Palmitate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Steareth-20, Chrysin, N-Hydroxysuccinimide, Butylene Glycol, Carbomer, Polysorbate 20, Glycol Distearate, Glyceryl Stearate, PEG-100 Stearate, Stearic Acid, Stearyl Alcohol, Phytonadione Epoxide, Vitis Vinifera Seed Oil, Persea Gratissima Oil, Tocopheryl Acetate, Allantoin, Titanium Dioxide, Tetrasodium EDTA, Triethanolamine, Phenoxyethanol, Ethylhexylglycerin

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.

It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.

The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.

The high linoleic acid content is particularly noteworthy for acne-prone skin.

Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.

One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).

This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.

On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.

Isopropyl Palmitate is a lightweight emollient made by combining isopropyl alcohol and palmitic acid.

It is an emollient that leaves skin feeling smooth and silky without leaving a greasy feel.

Typical usage concentrations range from 1-5%.

Human testing shows it's non-irritating and non-sensitizing, and the EU Scientific Committee on Consumer Safety (SCCS) has cleared it at very high levels (79% in leave-on products).

The one thing worth knowing about its comedogenic score of 3-4 is to keep it in perspective: these ratings come from old rabbit-ear tests using 100% of pure ingredient and doesn't reflect how it behaves at low levels in a finished product.

Because it is an ester of palmitic acid (C16), it falls into the range that the Malassezia yeast can feed on and is considered not fungal acne safe.

This ingredient is also known as Avocado oil. It's the cold-pressed oil from the flesh of the avocado fruit packed with fatty acids (mostly oleic acid).

The rich fatty acid profile allows it to function as a skin conditioning agent and emollient; it helps soften and smooth skin while reducing water loss.

Preclinical research has found that topical avocado oil increased collagen synthesis and reduced inflammation during wound healing, giving it some skin-repairing credibility.

The unsaponifiable fraction of the oil is also interesting: studies on avocado unsaponifiables showed that it helped skin produce more collagen and other structural compounds that support healing.

The CIR Expert Panel has found this ingredient to be non-irritating in formulations.

It's a great ingredient for dry or compromised skin. Just know it may not be fungal acne safe. This is because the oleic acid content falls within the range that Malassezia can use as a food source.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

02

Product index

Related product references

Product

Dr. Lara Devgan Peptide Eye Cream

Dr. Lara Devgan Peptide Eye Cream Ingredients in Dr. Lara Devgan Peptide Eye Cream explained: benefits, concerns, and detailed analysis of 28 ingredients including Water, Helianthus Annuus …

Source: skinsort.comView reference →
03

Comparison edit

Read side by side