Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Kiehl's Super Multi-Corrective Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

Kiehl's Super Multi-Corrective Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer This anti-aging moisturizer is formulated around Capryloyl Salicylic Acid and Adenosine to soften the look of wrinkles. This anti-aging night moisturizer is form

Kiehl's Super Multi-Corrective Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

This anti-aging moisturizer is formulated around Capryloyl Salicylic Acid and Adenosine to soften the look of wrinkles.

This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dicaprylyl Ether

Butyrospermum Parkii Butter

Hydroxypropyl Tetrahydropyrantriol

Isononyl Isononanoate

Propylene Glycol

Isopropyl Isostearate

Cetyl Alcohol

Dimethicone

Behenyl Alcohol

Candelilla Cera

Euphorbia Cerifera Cera

Glyceryl Stearate

Stearic Acid

Hydroxyethylpiperazine Ethane Sulfonic Acid

Palmitic Acid

Phenoxyethanol

Cetearyl Alcohol

Citric Acid

Carbomer

Capryloyl Salicylic Acid

Sodium Hydroxide

Caprylyl Glycol

PEG-100 Stearate

Vigna Aconitifolia Seed Extract

Tocopherol

Xanthan Gum

Cetearyl Glucoside

Sodium Cocoyl Glutamate

Sodium Hyaluronate

Disodium EDTA

Pentylene Glycol

Jasminum Officinale Flower Extract

Myristic Acid

Rosmarinus Officinalis Leaf Oil

Adenosine

Inonotus Obliquus Extract

Limonene

Linalool

Pelargonium Graveolens Flower Oil

Lavandula Angustifolia Oil

Rosa Damascena Flower Oil

Water, Glycerin, Dicaprylyl Ether, Butyrospermum Parkii Butter, Hydroxypropyl Tetrahydropyrantriol, Isononyl Isononanoate, Propylene Glycol, Isopropyl Isostearate, Cetyl Alcohol, Dimethicone, Behenyl Alcohol, Candelilla Cera, Euphorbia Cerifera Cera, Glyceryl Stearate, Stearic Acid, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Phenoxyethanol, Cetearyl Alcohol, Citric Acid, Carbomer, Capryloyl Salicylic Acid, Sodium Hydroxide, Caprylyl Glycol, PEG-100 Stearate, Vigna Aconitifolia Seed Extract, Tocopherol, Xanthan Gum, Cetearyl Glucoside, Sodium Cocoyl Glutamate, Sodium Hyaluronate, Disodium EDTA, Pentylene Glycol, Jasminum Officinale Flower Extract, Myristic Acid, Rosmarinus Officinalis Leaf Oil, Adenosine, Inonotus Obliquus Extract, Limonene, Linalool, Pelargonium Graveolens Flower Oil, Lavandula Angustifolia Oil, Rosa Damascena Flower Oil

Tapioca Starch

Dimethicone Crosspolymer

Retinol

Retinyl Propionate

Niacinamide

Palmitoyl Pentapeptide-4

Polyacrylamide

C13-14 Isoparaffin

DMDM Hydantoin

Polysorbate 20

Laureth-4

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Laureth-7

Dimethiconol

Polymethylsilsesquioxane

Aminomethyl Propanol

Titanium Dioxide

Iodopropynyl Butylcarbamate

Caprylic/Capric Triglyceride

Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
  4. 04Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
  5. 05In practice, that translates to a long shelf life and a consistently elegant skin feel.
  6. 06While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
  7. 07Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
  8. 08This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
  9. 09This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures…
  10. 10Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
  11. 11What it does:
  12. 12Dimethicone comes in different viscosities:
  13. 13Depending on the viscosity, dimethicone has different properties.
  14. 14Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
  15. 15This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
  16. 16Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
  17. 17Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.
  18. 18Dimethicone Crosspolymer is used to stabilize and thicken products. It also helps give products a silky feel.
  19. 19Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
  20. 20This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side