Kopari Tri-Peptide Lip Cloud Versus rhode Peptide Lip Treatment

Kopari Tri-Peptide Lip Cloud Versus rhode Peptide Lip Treatment

This anti-aging lip moisturizer is formulated around Ricinus Communis Seed Oil and Cocos Nucifera Oil to soften the look of wrinkles and hydrate lips.

This anti-aging lip moisturizer is formulated around Butyrospermum Parkii Butter and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate lips.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Ricinus Communis Seed Oil

Cocos Nucifera Oil

Capryloyl Glycerin/Sebacic Acid Copolymer

Diheptyl Succinate

Tribehenin

Prunus Armeniaca Kernel Oil

Brassica Campestris/Aleurites Fordi Oil Copolymer

Oryza Sativa Bran Oil

Oryza Sativa Bran Wax

Glyceryl Behenate

Ethylhexyl Palmitate

Water

Mentha Piperita Oil

Tocopherol

Menthol

Sorbitan Isostearate

Sodium Hyaluronate

CI 77492

CI 15850

Palmitoyl Tripeptide-1

Ricinus Communis Seed Oil, Cocos Nucifera Oil, Capryloyl Glycerin/Sebacic Acid Copolymer, Diheptyl Succinate, Tribehenin, Prunus Armeniaca Kernel Oil, Brassica Campestris/Aleurites Fordi Oil Copolymer, Oryza Sativa Bran Oil, Oryza Sativa Bran Wax, Glyceryl Behenate, Ethylhexyl Palmitate, Water, Mentha Piperita Oil, Tocopherol, Menthol, Sorbitan Isostearate, Sodium Hyaluronate, CI 77492, CI 15850, Palmitoyl Tripeptide-1

Hydrogenated Polyisobutene

Diisostearyl Malate

Butyrospermum Parkii Butter

Polybutene

Microcrystalline Wax

Synthetic Beeswax

Synthetic Wax

Octyldodecanol

Hydrogenated Poly(C6-14 Olefin)

Polyglyceryl-2 Triisostearate

Dimer Dilinoleyl Dimer Dilinoleate

Glyceryl Behenate/Eicosadioate

Triethyl Citrate

Tocopheryl Acetate

Tetrahexyldecyl Ascorbate

Orbignya Oleifera Seed Oil

Theobroma Grandiflorum Seed Butter

Lactic Acid

Stevioside

Synthetic Fluorphlogopite

Disteardimonium Hectorite

O-Cymen-5-Ol

Hydrogenated Polyisobutene, Diisostearyl Malate, Butyrospermum Parkii Butter, Polybutene, Microcrystalline Wax, Synthetic Beeswax, Synthetic Wax, Octyldodecanol, Hydrogenated Poly(C6-14 Olefin), Polyglyceryl-2 Triisostearate, Dimer Dilinoleyl Dimer Dilinoleate, Glyceryl Behenate/Eicosadioate, Triethyl Citrate, Tocopherol, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-1, Orbignya Oleifera Seed Oil, Theobroma Grandiflorum Seed Butter, Lactic Acid, Tribehenin, Stevioside, Ethylhexyl Palmitate, Sorbitan Isostearate, Synthetic Fluorphlogopite, Disteardimonium Hectorite, O-Cymen-5-Ol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ethylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid.

In cosmetics, it plays many roles:

One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day.

For most people, this is a well-tolerated and lightweight ingredient.

This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize.

Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.

That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Sorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol.

As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth.

In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%.

Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Tribehenin is the triglyceride of glycerin and behenic acid. It is an emollient that helps soften and condition skin.

Safety-wise, this is a well-vetted ingredient. Repeated-insult patch tests of 0.38% tribehenin did not trigger sensitization.

This ingredient may not be fungal acne safe because behenic acid falls into the chain-length range that Malassezia yeasts can feed on.

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