Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Krave Beauty Great Barrier Relief Versus Paula's Choice Resist Super Antioxidant Serum

Krave Beauty Great Barrier Relief Versus Paula's Choice Resist Super Antioxidant Serum This barrier-repair serum is formulated around Calophyllum Inophyllum Seed Oil and Niacinamide to strengthen the skin barrier and calm redness. This anti-aging serum is form

Krave Beauty Great Barrier Relief Versus Paula's Choice Resist Super Antioxidant Serum

This barrier-repair serum is formulated around Calophyllum Inophyllum Seed Oil and Niacinamide to strengthen the skin barrier and calm redness.

This anti-aging serum is formulated around Tetrahexyldecyl Ascorbate and Palmitoyl Tripeptide-5 to soften the look of wrinkles and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Calophyllum Inophyllum Seed Oil

Dipropylene Glycol

Niacinamide

Carthamus Tinctorius Seed Oil

Cetearyl Olivate

Polysorbate 60

Glyceryl Oleate

Octyldodecanol

Rosa Canina Fruit Oil

Sorbitan Oleate

Sorbitan Olivate

Coco-Caprylate/Caprate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Glycerin

Tocopheryl Acetate

Butylene Glycol

Caprylyl Glycol

Hydroxyacetophenone

Pentylene Glycol

Squalane

Urea

Xanthan Gum

Sorbitan Isostearate

1,2-Hexanediol

Hydrogenated Olive Oil Unsaponifiables

Disodium EDTA

Avena Sativa Kernel Flour

Magnesium Chloride

Sodium Hyaluronate

Glycine Soja Sterols

Lactic Acid

Caprylic/Capric Triglyceride

Glycosyl Trehalose

Acetyl Glutamine

Oleic Acid

Sodium PCA

Serine

Ceramide NP

Glycine

Water, Propanediol, Calophyllum Inophyllum Seed Oil, Dipropylene Glycol, Niacinamide, Carthamus Tinctorius Seed Oil, Cetearyl Olivate, Polysorbate 60, Glyceryl Oleate, Octyldodecanol, Rosa Canina Fruit Oil, Sorbitan Oleate, Sorbitan Olivate, Coco-Caprylate/Caprate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glycerin, Tocopheryl Acetate, Butylene Glycol, Caprylyl Glycol, Hydroxyacetophenone, Pentylene Glycol, Squalane, Urea, Xanthan Gum, Sorbitan Isostearate, 1,2-Hexanediol, Hydrogenated Olive Oil Unsaponifiables, Disodium EDTA, Avena Sativa Kernel Flour, Magnesium Chloride, Sodium Hyaluronate, Glycine Soja Sterols, Lactic Acid, Caprylic/Capric Triglyceride, Glycosyl Trehalose, Acetyl Glutamine, Oleic Acid, Sodium PCA, Serine, Ceramide NP, Glycine

Cyclopentasiloxane

Dimethicone

Tetrahexyldecyl Ascorbate

Palmitoyl Tripeptide-5

Tocotrienols

Tocopherol

Ubiquinone

Thioctic Acid

Magnesium Ascorbyl Phosphate

Ferulic Acid

Beta-Glucan

Superoxide Dismutase

Epigallocatechin Gallate

Ergothioneine

Glutathione

Xanthophylls

Glycine Soja Seed Extract

Arctostaphylos Uva Ursi Leaf Extract

Lupinus Albus Seed Extract

Curcuma Longa Root

Elaeis Guineensis Oil

Phenoxyethanol

Cyclopentasiloxane, Dimethicone, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-5, Ceramide NP, Tocotrienols, Tocopherol, Ubiquinone, Thioctic Acid, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Ferulic Acid, Beta-Glucan, Superoxide Dismutase, Epigallocatechin Gallate, Ergothioneine, Glutathione, Xanthophylls, Glycine Soja Seed Extract, Glycerin, Arctostaphylos Uva Ursi Leaf Extract, Lupinus Albus Seed Extract, Curcuma Longa Root, Elaeis Guineensis Oil, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Niacinamide
  3. 03Glycerin
  4. 04Butylene Glycol
  5. 05Propanediol
  6. 06Alpha-Arbutin
  7. 071,2-Hexanediol
  8. 08Hydroxyacetophenone
  9. 09Acrylates/C10-30 Alkyl Acrylate Crosspolymer
  10. 10Tromethamine
  11. 11Glycereth-25 PCA Isostearate
  12. 12Ethylhexylglycerin
  13. 13Caprylic/Capric Triglyceride
  14. 14Macadamia Ternifolia Seed Oil
  15. 15Zea Mays Kernel Extract
  16. 16Disodium EDTA
  17. 17Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
  18. 18Hydrogenated Lecithin
  19. 19Retinol
  20. 20Hyaluronic Acid
Source · skinsort.com
02

Product index

Related product references

Product

Paula's Choice The Unscrub

Paula's Choice The Unscrub Paula's Choice The Unscrub ingredients explained: Aqua, Jojoba Esters (Cleansing Beads), Caprylic/Capric Triglyceride (Skin-Replenishing), Glycerin (Skin Replenis…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side