La Mer The Eye Concentrate Versus Biossance Squalane + Peptide Eye Gel

La Mer The Eye Concentrate Versus Biossance Squalane + Peptide Eye Gel

This anti-aging eye moisturizer is formulated around Acetyl Hexapeptide-8 and Caffeine to soften the look of wrinkles.

This anti-aging eye moisturizer is formulated around Squalane and Niacinamide to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Algae Extract

Water

Dimethicone

Isododecane

Glycerin

Hydrogenated Polyisobutene

Trisiloxane

Caprylic/Capric/Myristic/Stearic Triglyceride

Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer

Caprylic/Capric Triglyceride

Maris Sal

Faex Extract

Helichrysum Arenarium Extract

Sesamum Indicum Seed Oil

Medicago Sativa Seed Powder

Helianthus Annuus Seedcake

Prunus Amygdalus Dulcis Seed Meal

Eucalyptus Globulus Leaf Oil

Sodium Gluconate

Copper Gluconate

Calcium Gluconate

Magnesium Gluconate

Zinc Gluconate

Tocopheryl Succinate

Niacin

Sesamum Indicum Seed Powder

Asparagopsis Armata Extract

Laminaria Digitata Extract

Molasses Extract

Phytosphingosine

Ecklonia Cava Extract

Corallina Officinalis Extract

Sodium Hyaluronate

Sigesbeckia Orientalis Extract

Polygonum Fagopyrum Seed Extract

Brassica Campestris Seed Oil

Polyglyceryl-3 Diisostearate

Glycyrrhiza Glabra Root Extract

Ascophyllum Nodosum Extract

Citrus Aurantifolia Peel Extract

Cucumis Sativus Fruit Extract

Acetyl Hexapeptide-8

Althaea Officinalis Root Extract

Oryza Sativa Bran Extract

Tocopheryl Acetate

Saccharomyces Lysate Extract

Macadamia Integrifolia Seed Oil

Dipeptide-2

Glyceryl Triacetyl Ricinoleate

Palmitoyl Tetrapeptide-7

Caffeine

Tetraacetylphytosphingosine

Whey Protein

Acetyl Glucosamine

Triethylhexanoin

Sorbitol

Hordeum Vulgare Extract

Glycine Soja Protein

Cholesterol

Hydrolyzed Yeast Protein

Isononyl Isononanoate

Propylene Glycol Dicaprate

Cetyl PEG/PPG-10/1 Dimethicone

Caprylyl Glycol

Sucrose

Polysilicone-11

Dimethicone Crosspolymer

Dimethicone Crosspolymer-3

Silica

Nylon-12

Trimethylsiloxysilicate

Steareth-20

Calcium Chloride

Hesperidin Methyl Chalcone

PEG/PPG-18/18 Dimethicone

Alumina

Triethoxycaprylylsilane

Hydrogenated Vegetable Oil

Alcohol Denat.

Propanediol

Parfum

BHT

Phenoxyethanol

Potassium Sorbate

Chlorhexidine Digluconate

Sodium Benzoate

Mica

CI 77891

Algae Extract, Water, Dimethicone, Isododecane, Glycerin, Hydrogenated Polyisobutene, Trisiloxane, Caprylic/Capric/Myristic/Stearic Triglyceride, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Caprylic/Capric Triglyceride, Maris Sal, Faex Extract, Helichrysum Arenarium Extract, Sesamum Indicum Seed Oil, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake, Prunus Amygdalus Dulcis Seed Meal, Eucalyptus Globulus Leaf Oil, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Sesamum Indicum Seed Powder, Asparagopsis Armata Extract, Laminaria Digitata Extract, Molasses Extract, Phytosphingosine, Ecklonia Cava Extract, Corallina Officinalis Extract, Sodium Hyaluronate, Sigesbeckia Orientalis Extract, Polygonum Fagopyrum Seed Extract, Brassica Campestris Seed Oil, Polyglyceryl-3 Diisostearate, Glycyrrhiza Glabra Root Extract, Ascophyllum Nodosum Extract, Citrus Aurantifolia Peel Extract, Cucumis Sativus Fruit Extract, Acetyl Hexapeptide-8, Althaea Officinalis Root Extract, Oryza Sativa Bran Extract, Tocopheryl Acetate, Saccharomyces Lysate Extract, Macadamia Integrifolia Seed Oil, Dipeptide-2, Glyceryl Triacetyl Ricinoleate, Palmitoyl Tetrapeptide-7, Caffeine, Tetraacetylphytosphingosine, Whey Protein, Acetyl Glucosamine, Triethylhexanoin, Sorbitol, Hordeum Vulgare Extract, Glycine Soja Protein, Cholesterol, Hydrolyzed Yeast Protein, Isononyl Isononanoate, Propylene Glycol Dicaprate, Cetyl PEG/PPG-10/1 Dimethicone, Caprylyl Glycol, Sucrose, Polysilicone-11, Dimethicone Crosspolymer, Dimethicone Crosspolymer-3, Silica, Nylon-12, Trimethylsiloxysilicate, Steareth-20, Calcium Chloride, Hesperidin Methyl Chalcone, PEG/PPG-18/18 Dimethicone, Alumina, Triethoxycaprylylsilane, Hydrogenated Vegetable Oil, Alcohol Denat., Propanediol, Parfum, BHT, Phenoxyethanol, Potassium Sorbate, Chlorhexidine Digluconate, Sodium Benzoate, Mica, CI 77891

Aloe Barbadensis Leaf Juice

Squalane

Niacinamide

Panthenol

Chondrus Crispus Extract

Malus Domestica Fruit Cell Culture Extract

Acetyl Tetrapeptide-5

Tocopherol

Pentylene Glycol

Tetrahexyldecyl Ascorbate

Camellia Sinensis Leaf Extract

Lycium Barbarum Fruit Extract

Lycopene

Vitis Vinifera Skin Extract

Acacia Senegal Gum

Xanthan Gum

Carbomer

Ethyl Lauroyl Arginate Hcl

Lecithin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Citric Acid

Water, Aloe Barbadensis Leaf Juice, Squalane, Niacinamide, Glycerin, Panthenol, Chondrus Crispus Extract, Malus Domestica Fruit Cell Culture Extract, Acetyl Tetrapeptide-5, Acetyl Hexapeptide-8, Tocopherol, Pentylene Glycol, Cucumis Sativus Fruit Extract, Tetrahexyldecyl Ascorbate, Camellia Sinensis Leaf Extract, Lycium Barbarum Fruit Extract, Lycopene, Vitis Vinifera Skin Extract, Sodium Hyaluronate, Caffeine, Acacia Senegal Gum, Dimethicone Crosspolymer, Xanthan Gum, Carbomer, Ethyl Lauroyl Arginate Hcl, Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Silica, Phenoxyethanol, Potassium Sorbate, Citric Acid, Caprylyl Glycol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.

As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.

Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.

You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.

Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.

Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

This extract comes from cucumber. Cucumbers are mostly made up of water (95%), and the other 5% is composed of: vitamin C, caffeic acid, fatty acids, amino acids, and other minerals.

Cucumbers have anti-inflammatory, barrier repair, and hydrating properties.

They contain shikimate dehydrigenase, an enzyme shown to help reduce inflammation and soothe the skin.

The amino acids found in cucumbers help nourish our skin's natural acid mantle (it's an important part of our skin barrier). This slightly acidic film acts as a barrier to protect us from bacteria, viruses, and other contaminants.

Unless you have an allergy to cucumbers, this is generally a non-irritating ingredient.

Fun fact: Cucumis Sativus is native to South Asia and can now be found on every continent.

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Dimethicone Crosspolymer is used to stabilize and thicken products. It also helps give products a silky feel.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Silica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.

Though it has exfoliant properties, the function of silica varies depending on the product.

The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.

It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.

In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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