Skin science article
La Roche-Posay 10% Pure Vitamin C Serum Versus Paula's Choice Hyaluronic Acid Booster
La Roche-Posay 10% Pure Vitamin C Serum Versus Paula's Choice Hyaluronic Acid Booster This brightening serum is formulated around Ascorbic Acid and Salicylic Acid to brighten dull-looking skin and refine skin texture. This hydrating treatment is formulated aro
La Roche-Posay 10% Pure Vitamin C Serum Versus Paula's Choice Hyaluronic Acid Booster
This brightening serum is formulated around Ascorbic Acid and Salicylic Acid to brighten dull-looking skin and refine skin texture.
This hydrating treatment is formulated around Sodium Hyaluronate and Hyaluronic Acid to hydrate skin and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Ascorbic Acid
Cyclohexasiloxane
Glycerin
Alcohol Denat.
Potassium Hydroxide
Polymethylsilsesquioxane
Polysilicone-11
Dimethicone
Propylene Glycol
Pentaerythrityl Tetraethylhexanoate
C13-14 Isoparaffin
Tocopherol
Sodium Hyaluronate
Hydrolyzed Hyaluronic Acid
Adenosine
Acetyl Dipeptide-1 Cetyl Ester
PEG-20 Methyl Glucose Sesquistearate
Poloxamer 338
Salicylic Acid
Polyacrylamide
Toluene Sulfonic Acid
Ammonium Polyacryloyldimethyl Taurate
Xanthan Gum
Caprylyl Glycol
Disodium EDTA
BHT
Laureth-7
Parfum
Water, Ascorbic Acid, Cyclohexasiloxane, Glycerin, Alcohol Denat., Potassium Hydroxide, Polymethylsilsesquioxane, Polysilicone-11, Dimethicone, Propylene Glycol, Pentaerythrityl Tetraethylhexanoate, C13-14 Isoparaffin, Tocopherol, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Adenosine, Acetyl Dipeptide-1 Cetyl Ester, PEG-20 Methyl Glucose Sesquistearate, Poloxamer 338, Salicylic Acid, Polyacrylamide, Toluene Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Xanthan Gum, Caprylyl Glycol, Disodium EDTA, BHT, Laureth-7, Parfum
Hyaluronic Acid
Ceramide NP
Ceramide AP
Ceramide EOP
Phytosphingosine
Yeast Extract
Cholesterol
Panthenol
Silanetriol
Butylene Glycol
Sodium Lauroyl Lactylate
Carbomer
Citric Acid
Sodium Hydroxide
Polysorbate 20
Ethylhexylglycerin
Phenoxyethanol
Water, Glycerin, Sodium Hyaluronate, Hyaluronic Acid, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Yeast Extract, Adenosine, Cholesterol, Panthenol, Silanetriol, Butylene Glycol, Sodium Lauroyl Lactylate, Carbomer, Xanthan Gum, Citric Acid, Sodium Hydroxide, Polysorbate 20, Ethylhexylglycerin, Phenoxyethanol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.