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Skin science article

La Roche-Posay Effaclar Duo+ Global Acne Treatment Versus Paula's Choice Regular Strength Daily Skin Clearing Treatment with 2.5% Benzoyl Peroxide

La Roche-Posay Effaclar Duo+ Global Acne Treatment Versus Paula's Choice Regular Strength Daily Skin Clearing Treatment with 2.5% Benzoyl Peroxide This acne treatment is formulated around Niacinamide and Zinc PCA to clear breakouts and balance excess oil. This

La Roche-Posay Effaclar Duo+ Global Acne Treatment Versus Paula's Choice Regular Strength Daily Skin Clearing Treatment with 2.5% Benzoyl Peroxide

This acne treatment is formulated around Niacinamide and Zinc PCA to clear breakouts and balance excess oil.

This acne treatment is formulated around Benzoyl Peroxide and Bisabolol to clear breakouts and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dimethicone

Isocetyl Stearate

Niacinamide

Isopropyl Lauroyl Sarcosinate

Silica

Ammonium Polyacryloyldimethyl Taurate

Methyl Methacrylate Crosspolymer

Sodium Hydroxide

Poloxamer 338

Polysorbate 80

Mannose

Xanthan Gum

Zinc PCA

Isohexadecane

2-Oleamido-1,3-Octadecanediol

Capryloyl Salicylic Acid

Caprylyl Glycol

Piroctone Olamine

Myristyl Myristate

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Sorbitan Oleate

Disodium EDTA

Potassium Cetyl Phosphate

Vitreoscilla Ferment

Aluminum Starch Octenylsuccinate

Glyceryl Stearate Se

Parfum

Water, Glycerin, Dimethicone, Isocetyl Stearate, Niacinamide, Isopropyl Lauroyl Sarcosinate, Silica, Ammonium Polyacryloyldimethyl Taurate, Methyl Methacrylate Crosspolymer, Sodium Hydroxide, Poloxamer 338, Polysorbate 80, Mannose, Xanthan Gum, Zinc PCA, Isohexadecane, 2-Oleamido-1,3-Octadecanediol, Capryloyl Salicylic Acid, Caprylyl Glycol, Piroctone Olamine, Myristyl Myristate, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Sorbitan Oleate, Disodium EDTA, Potassium Cetyl Phosphate, Vitreoscilla Ferment, Aluminum Starch Octenylsuccinate, Glyceryl Stearate Se, Parfum

Propylene Glycol

Benzoyl Peroxide

Bisabolol

Allantoin

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Hydroxyethylcellulose

Sodium Citrate

Laureth-4

Hexylene Glycol

Phenoxyethanol

Water, Propylene Glycol, Benzoyl Peroxide, Bisabolol, Allantoin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydroxyethylcellulose, Sodium Citrate, Laureth-4, Caprylyl Glycol, Sodium Hydroxide, Disodium EDTA, Hexylene Glycol, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  7. 07Topically, glycerin does several things at once:
  8. 08Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  9. 09Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  10. 10This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  11. 11Just know very high concentrations (>40%) can feel tacky in low humidity.
  12. 12Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  13. 13Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
  14. 14So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
  15. 15You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Source · skinsort.com
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Product index

Related product references

03

Comparison edit

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