Skin science article
La Roche-Posay Hyalu B5 Face Serum with Hyaluronic Acid Versus NeoStrata Skin Active Triple Therapy Lifting Serum
La Roche-Posay Hyalu B5 Face Serum with Hyaluronic Acid Versus NeoStrata Skin Active Triple Therapy Lifting Serum This hydrating serum is formulated around Panthenol and Madecassoside to hydrate skin and strengthen the skin barrier. This anti-aging serum is fo
La Roche-Posay Hyalu B5 Face Serum with Hyaluronic Acid Versus NeoStrata Skin Active Triple Therapy Lifting Serum
This hydrating serum is formulated around Panthenol and Madecassoside to hydrate skin and strengthen the skin barrier.
This anti-aging serum is formulated around Gluconolactone to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Alcohol Denat.
Propylene Glycol
Panthenol
Pentylene Glycol
Dimethicone
PEG-6 Caprylic/Capric Glycerides
PPG-6-Decyltetradeceth-30
Glyceryl Isostearate
Madecassoside
Sodium Hyaluronate
Ammonium Polyacryloyldimethyl Taurate
Disodium EDTA
Hydrolyzed Hyaluronic Acid
Caprylyl Glycol
Citric Acid
Xanthan Gum
Butylene Glycol
Tocopherol
Phenoxyethanol
Parfum
Water, Glycerin, Alcohol Denat., Propylene Glycol, Panthenol, Pentylene Glycol, Dimethicone, PEG-6 Caprylic/Capric Glycerides, PPG-6-Decyltetradeceth-30, Glyceryl Isostearate, Madecassoside, Sodium Hyaluronate, Ammonium Polyacryloyldimethyl Taurate, Disodium EDTA, Hydrolyzed Hyaluronic Acid, Caprylyl Glycol, Citric Acid, Xanthan Gum, Butylene Glycol, Tocopherol, Phenoxyethanol, Parfum
PEG-8
Gluconolactone
1,2-Hexanediol
Cyclopentasiloxane
PEG-12 Dimethicone
Polymethylsilsesquioxane
Acetyl Tyrosinamide
Cyclohexasiloxane
Hydrolyzed Sodium Hyaluronate
Dimethiconol
Biosaccharide Gum-1
Polyacrylate-13
Polyisobutene
Isopropyl Myristate
Polysorbate 20
Sodium Sulfite
BHT
Ammonium Hydroxide
Methyldihydrojasmonate
2,6-Dimethyl-7-Octen-2-Ol
Ethyl Acetoacetate
Methyl Benzodioxepinone
Chlorphenesin
CI 17200
CI 42090
Water, PEG-8, Gluconolactone, 1,2-Hexanediol, Cyclopentasiloxane, Glycerin, Pentylene Glycol, PEG-12 Dimethicone, Polymethylsilsesquioxane, Acetyl Tyrosinamide, Cyclohexasiloxane, Hydrolyzed Sodium Hyaluronate, Dimethiconol, Biosaccharide Gum-1, Polyacrylate-13, Polyisobutene, Isopropyl Myristate, Polysorbate 20, Sodium Sulfite, BHT, Ammonium Hydroxide, Caprylyl Glycol, Xanthan Gum, Methyldihydrojasmonate, 2,6-Dimethyl-7-Octen-2-Ol, Ethyl Acetoacetate, Methyl Benzodioxepinone, Phenoxyethanol, Chlorphenesin, CI 17200, CI 42090
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.