Skin science article
La Roche-Posay Pigmentclar Serum Visible Dark Spot Reducer Versus Drunk Elephant Protini Powerpeptide Resurfacing Serum
La Roche-Posay Pigmentclar Serum Visible Dark Spot Reducer Versus Drunk Elephant Protini Powerpeptide Resurfacing Serum This brightening serum is formulated around Niacinamide and Phenylethyl Resorcinol to fade the look of dark spots and brighten dull-looking
La Roche-Posay Pigmentclar Serum Visible Dark Spot Reducer Versus Drunk Elephant Protini Powerpeptide Resurfacing Serum
This brightening serum is formulated around Niacinamide and Phenylethyl Resorcinol to fade the look of dark spots and brighten dull-looking skin.
This smoothing serum is formulated around Lactic Acid and Sh-Oligopeptide-1 to refine skin texture and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dimethicone
Alcohol Denat.
Niacinamide
Isopropyl Lauroyl Sarcosinate
Octyldodecanol
PEG-20 Methyl Glucose Sesquistearate
Dimethiconol
Cetearyl Ethylhexanoate
Isohexadecane
Sodium Hyaluronate
Ginkgo Biloba Leaf Extract
Phenylethyl Resorcinol
Poloxamer 338
Ammonium Polyacryloyldimethyl Taurate
Disodium EDTA
Isopropyl Myristate
Capryloyl Salicylic Acid
Xanthan Gum
Ferulic Acid
Polysorbate 80
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Phenoxyethanol
CI 77891
Mica
Parfum
Water, Glycerin, Dimethicone, Alcohol Denat., Niacinamide, Isopropyl Lauroyl Sarcosinate, Octyldodecanol, PEG-20 Methyl Glucose Sesquistearate, Dimethiconol, Cetearyl Ethylhexanoate, Isohexadecane, Sodium Hyaluronate, Ginkgo Biloba Leaf Extract, Phenylethyl Resorcinol, Poloxamer 338, Ammonium Polyacryloyldimethyl Taurate, Disodium EDTA, Isopropyl Myristate, Capryloyl Salicylic Acid, Xanthan Gum, Ferulic Acid, Polysorbate 80, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Phenoxyethanol, CI 77891, Mica, Parfum
Lactic Acid
Dicaprylyl Carbonate
Squalane
Sodium Hydroxide
Glycine Max Seed Extract
Sclerocarya Birrea Seed Oil
Camellia Sinensis Seed Oil
Sodium PCA
Caprylic/Capric Triglyceride
Borago Officinalis Seed Oil
Tremella Fuciformis Polysaccharide
Tocotrienols
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-9
Sh-Polypeptide-11
Copper Palmitoyl Heptapeptide-14
Heptapeptide-15 Palmitate
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-38
Palmitoyl Hexapeptide-12
Tripeptide-1
Pyrus Malus Fruit Extract
Propanediol
Panthenol
Sodium Hyaluronate Crosspolymer
Sodium Lactate
PCA
Alanine
Arginine
Glycine
Histidine
Isoleucine
Phenylalanine
Proline
Serine
Threonine
Valine
Adenosine
Nymphaea Alba Root Extract
Bacillus/Folic Acid Ferment Filtrate Extract
Symphytum Officinale Callus Culture Extract
Dextran
Oryza Sativa Bran Oil
Linoleic Acid
Linolenic Acid
Butylene Glycol
Acetyl Glutamine
Coconut Alkanes
Coco-Caprylate/Caprate
Pentylene Glycol
Isomalt
Lecithin
Aspartic Acid
Phytosphingosine
Phospholipids
Glycine Soja Sterols
Tocopherol
Citric Acid
Lactic Acid/Glycolic Acid Copolymer
Polyvinyl Alcohol
Sodium Benzoate
Hydroxypropyl Cyclodextrin
Polysorbate 20
Caprylyl Glycol
Phenylpropanol
Chlorphenesin
Carbomer
Glyceryl Caprylate
Ethylhexylglycerin
Water, Glycerin, Lactic Acid, Dicaprylyl Carbonate, Squalane, Sodium Hydroxide, Glycine Max Seed Extract, Sclerocarya Birrea Seed Oil, Camellia Sinensis Seed Oil, Sodium PCA, Caprylic/Capric Triglyceride, Borago Officinalis Seed Oil, Tremella Fuciformis Polysaccharide, Tocotrienols, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38, Palmitoyl Hexapeptide-12, Tripeptide-1, Pyrus Malus Fruit Extract, Propanediol, Sodium Hyaluronate, Panthenol, Sodium Hyaluronate Crosspolymer, Sodium Lactate, PCA, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Adenosine, Nymphaea Alba Root Extract, Bacillus/Folic Acid Ferment Filtrate Extract, Symphytum Officinale Callus Culture Extract, Dextran, Oryza Sativa Bran Oil, Linoleic Acid, Linolenic Acid, Butylene Glycol, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Pentylene Glycol, Isomalt, Lecithin, Xanthan Gum, Aspartic Acid, Phytosphingosine, Phospholipids, Glycine Soja Sterols, Tocopherol, Citric Acid, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenoxyethanol, Sodium Benzoate, Hydroxypropyl Cyclodextrin, Polysorbate 20, Caprylyl Glycol, Phenylpropanol, Chlorphenesin, Carbomer, Glyceryl Caprylate, Ethylhexylglycerin
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.