Skin science article
La Roche-Posay Toleriane Double Repair Face Moisturizer Versus The INKEY List Vitamin B, C and E Moisturizer
La Roche-Posay Toleriane Double Repair Face Moisturizer Versus The INKEY List Vitamin B, C and E Moisturizer This barrier-repair moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and hydrate skin. This brightening moistur
La Roche-Posay Toleriane Double Repair Face Moisturizer Versus The INKEY List Vitamin B, C and E Moisturizer
This barrier-repair moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and hydrate skin.
This brightening moisturizer is formulated around Niacinamide and Sodium Ascorbyl Phosphate to brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Squalane
Dimethicone
Zea Mays Starch
Niacinamide
Ammonium Polyacryloyldimethyl Taurate
Myristyl Myristate
Stearic Acid
Ceramide NP
Potassium Cetyl Phosphate
Glyceryl Stearate Se
Sodium Hydroxide
Myristic Acid
Palmitic Acid
Capryloyl Glycine
Caprylyl Glycol
Xanthan Gum
Water, Glycerin, Squalane, Dimethicone, Zea Mays Starch, Niacinamide, Ammonium Polyacryloyldimethyl Taurate, Myristyl Myristate, Stearic Acid, Ceramide NP, Potassium Cetyl Phosphate, Glyceryl Stearate Se, Sodium Hydroxide, Myristic Acid, Palmitic Acid, Capryloyl Glycine, Caprylyl Glycol, Xanthan Gum
Cetearyl Alcohol
Caprylic/Capric Triglyceride
Cocos Nucifera Oil
Phenoxyethanol
Benzyl Alcohol
Carbomer
Panthenol
Sodium Ascorbyl Phosphate
Sodium Hyaluronate
Tocopheryl Acetate
Ethylhexylglycerin
Dehydroacetic Acid
Lecithin
Trisodium Ethylenediamine Disuccinate
Ascorbyl Palmitate
Tocopherol
Helianthus Annuus Seed Oil
Water, Glycerin, Glyceryl Stearate Se, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Cocos Nucifera Oil, Stearic Acid, Phenoxyethanol, Benzyl Alcohol, Carbomer, Sodium Hydroxide, Niacinamide, Panthenol, Sodium Ascorbyl Phosphate, Sodium Hyaluronate, Tocopheryl Acetate, Ethylhexylglycerin, Dehydroacetic Acid, Lecithin, Trisodium Ethylenediamine Disuccinate, Ascorbyl Palmitate, Tocopherol, Helianthus Annuus Seed Oil
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Stearate Se is a self-emulsifying (SE) form of glyceryl stearate. Self-emusifying means this ingredient automatically blends with water. It is an emulsifier, emollient, and cleansing agent.
As an emulsifier, Glyceryl Stearate Se prevents ingredients such as oil and water from separating. It is also a surfactant, meaning it helps cleanse the skin. Surfactants help gather oil, dirt, and other pollutants so they may be rinsed away easily.
Emollients help your skin stay smooth and soft. It does so by creating a film on top of the skin that helps trap moisture in.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!