Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Labo-H Hair Loss Care Scalp Ampoule Tonic Versus Some By Mi Cica Peptide Anti Hair Loss Derma Scalp Tonic

Labo-H Hair Loss Care Scalp Ampoule Tonic Versus Some By Mi Cica Peptide Anti Hair Loss Derma Scalp Tonic What's inside Key Ingredients Benefits Concerns Ingredients Side-by-side Water Alcohol Denat. Camellia Sinensis Leaf Extract PEG-60 Hydrogenated Castor Oi

Labo-H Hair Loss Care Scalp Ampoule Tonic Versus Some By Mi Cica Peptide Anti Hair Loss Derma Scalp Tonic

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Alcohol Denat.

Camellia Sinensis Leaf Extract

PEG-60 Hydrogenated Castor Oil

Caprylyl Glycol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Menthol

Dextrin

Propanediol

Aminomethyl Propanol

Disodium EDTA

Ethylhexylglycerin

Mentha Piperita Oil

Illicium Verum Fruit/Seed Oil

Rosmarinus Officinalis Leaf Oil

Juniperus Virginiana Oil

Lactobacillus Ferment Lysate

Mentha Arvensis Leaf Oil

Saccharomyces/Barley Seed Ferment Filtrate

Glycine Max Seed Extract

Butylene Glycol

Eucalyptus Globulus Leaf Oil

Ocimum Basilicum Oil

1,2-Hexanediol

Zingiber Officinale Root Extract

Biotin

Anthemis Nobilis Flower Oil

Sodium Hyaluronate

Viola Odorata Leaf Extract

Tocopherol

Hydrolyzed Hyaluronic Acid

Sodium Hyaluronate Crosspolymer

Humulus Lupulus Extract

Hyaluronic Acid

Sodium Acetylated Hyaluronate

Water, Alcohol Denat., Camellia Sinensis Leaf Extract, PEG-60 Hydrogenated Castor Oil, Caprylyl Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Menthol, Dextrin, Propanediol, Aminomethyl Propanol, Disodium EDTA, Ethylhexylglycerin, Mentha Piperita Oil, Illicium Verum Fruit/Seed Oil, Rosmarinus Officinalis Leaf Oil, Juniperus Virginiana Oil, Lactobacillus Ferment Lysate, Mentha Arvensis Leaf Oil, Saccharomyces/Barley Seed Ferment Filtrate, Glycine Max Seed Extract, Butylene Glycol, Eucalyptus Globulus Leaf Oil, Ocimum Basilicum Oil, 1,2-Hexanediol, Zingiber Officinale Root Extract, Biotin, Anthemis Nobilis Flower Oil, Sodium Hyaluronate, Viola Odorata Leaf Extract, Tocopherol, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Humulus Lupulus Extract, Hyaluronic Acid, Sodium Acetylated Hyaluronate

Tromethamine

Salicylic Acid

Panthenol

Mentha Piperita Leaf Extract

Mentha Viridis Extract

Mentha Rotundifolia Leaf Extract

Nigella Sativa Seed Extract

Oryza Sativa Extract

Ribes Nigrum Fruit Extract

Sesamum Indicum Sprout Extract

Salvia Hispanica Seed Extract

Vaccinium Angustifolium Fruit Extract

Hydrolyzed Centella Asiatica Extract

Madecassoside

Madecassic Acid

Asiaticoside

Asiatic Acid

Houttuynia Cordata Extract

Leonurus Sibiricus Flower/Leaf/Stem Extract

Nelumbo Nucifera Flower Extract

Artemisia Vulgaris Extract

Parfum

Water, Alcohol Denat., Menthol, Tromethamine, Salicylic Acid, Panthenol, Biotin, Butylene Glycol, Mentha Piperita Leaf Extract, Mentha Viridis Extract, Mentha Rotundifolia Leaf Extract, Glycine Max Seed Extract, Nigella Sativa Seed Extract, Oryza Sativa Extract, Ribes Nigrum Fruit Extract, Sesamum Indicum Sprout Extract, Salvia Hispanica Seed Extract, Vaccinium Angustifolium Fruit Extract, Hydrolyzed Centella Asiatica Extract, Madecassoside, Madecassic Acid, Asiaticoside, Asiatic Acid, Camellia Sinensis Leaf Extract, Houttuynia Cordata Extract, Leonurus Sibiricus Flower/Leaf/Stem Extract, Nelumbo Nucifera Flower Extract, Artemisia Vulgaris Extract, 1,2-Hexanediol, Ethylhexylglycerin, Caprylyl Glycol, Parfum

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

The "denat" part just means "denatured"; common denaturants include Denatonium Benzoate, t-butyl alcohol, and Diethyl Phthalate. This step makes the alcohol undrinkable (and lets brand skip taxes related to beverage alcohol).

This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin.

However, alcohol denat. is not all that bad.

Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.

This also helps other ingredients become better absorbed upon application.

Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.

Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.

The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list.

One thing to note: People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency.

The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used).

Also...

This ingredient has antimicrobial and solvent properties.

The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.

Look for formulas that contain glycerin, hyaluronic acid, or panthenol if you want to offset any drying effect.

This ingredient will trip away your skin's natural oils/lipids that help it lock in moisture. This can worsen dryness, trigger eczema flare-ups, and aggravate rosacea.

Be sure to patch test any product with this ingredient if you have dry or sensitive skin, eczema, or rosacea.

Biotin is a B vitamin that is naturally produced by our bodies. It is also called Vitamin H.

Our bodies use biotin in the metabolism process. It also helps our bodies use enzymes and move nutrients around. A biotin deficiency can lead to brittle hair and nails.

More research is needed on applying biotin topically. However, taking biotin orally has been shown to help nourish the skin, hair, and nails. They play a role in forming skin-hydrating fatty acids.

Biotin is water-soluble. It can be found in foods such as fish, eggs, dairy, nuts, and meat. Vitamin H stands for "haar" and "haut". These are the German words for hair and skin.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Camellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.

Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.

Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.

In lab-grown skin models, this translated to younger, healthier, and stronger skin.

There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.

Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.

A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.

The quality of the extract matters a lot here:

Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.

Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycine Max Seed Extract comes from the Soybean. This bean is native to Asia.

Soybeans are rich in antioxidants. Antioxidants may improve the signs of aging.

Studies show soy may help fade hyperpigmentation from UVB. It does so by disrupting the melanin process caused by UVB induced skin inflammation.

Two powerful components found in the wild soybean include genistein and diadzein. These two isoflavones are potent antioxidants with anti-inflammatory properties. Genistein in particular has been found to prevent redness caused by UV exposure.

Soybeans are rich in proteins and are part of the legume family. Foods made with soybeans include tofu, soymilk, edamame, miso, and soy sauce.

Menthol is a compound found in mint plants, such as peppermint. In its pure form, it is a clear crystalline substance.

Menthol is known for its cooling sensation; however, the cooling is actually from your skin being sensitized. Menthol can worsen rosacea. We recommend speaking with a professional if you have concerns.

Menthol also has antimicrobial properties.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

02

Product index

Related product references

03

Comparison edit

Read side by side