Skin science article
Lador Keratin LPP Shampoo Versus Some By Mi Cica Peptide Anti Hair Loss Derma Scalp Shampoo
Lador Keratin LPP Shampoo Versus Some By Mi Cica Peptide Anti Hair Loss Derma Scalp Shampoo What's inside Key Ingredients Benefits Concerns Ingredients Side-by-side Water Cocamidopropyl Betaine Disodium Laureth Sulfosuccinate Lauramine Oxide Tea-Cocoyl Glutama
Lador Keratin LPP Shampoo Versus Some By Mi Cica Peptide Anti Hair Loss Derma Scalp Shampoo
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Cocamidopropyl Betaine
Disodium Laureth Sulfosuccinate
Lauramine Oxide
Tea-Cocoyl Glutamate
Glycerin
Butylene Glycol
Lauramide DEA
PEG-120 Methyl Glucose Dioleate
Sodium Chloride
Sodium Benzoate
PEG-7 Glyceryl Cocoate
PPG-3 Caprylyl Ether
Citric Acid
Polyquaternium-10
Betaine
Chitosan
1,2-Hexanediol
Hydrolyzed Wheat Protein
Hydrolyzed Soy Protein
Hydrolyzed Corn Protein
Ethylhexylglycerin
Hydrolyzed Silk
Hydroxyacetophenone
Sodium Hyaluronate
Trehalose
Dipropylene Glycol
Zein
Argania Spinosa Kernel Oil
Persea Gratissima Oil
Camellia Japonica Seed Oil
Simmondsia Chinensis Seed Oil
Hydrolyzed Keratin
Pentylene Glycol
Benzyl Salicylate
Citronellol
Hexyl Cinnamal
Hydroxycitronellal
Parfum
Water, Cocamidopropyl Betaine, Disodium Laureth Sulfosuccinate, Lauramine Oxide, Tea-Cocoyl Glutamate, Glycerin, Butylene Glycol, Lauramide DEA, PEG-120 Methyl Glucose Dioleate, Sodium Chloride, Sodium Benzoate, PEG-7 Glyceryl Cocoate, PPG-3 Caprylyl Ether, Citric Acid, Polyquaternium-10, Betaine, Chitosan, 1,2-Hexanediol, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Hydrolyzed Corn Protein, Ethylhexylglycerin, Hydrolyzed Silk, Hydroxyacetophenone, Sodium Hyaluronate, Trehalose, Dipropylene Glycol, Zein, Argania Spinosa Kernel Oil, Persea Gratissima Oil, Camellia Japonica Seed Oil, Simmondsia Chinensis Seed Oil, Hydrolyzed Keratin, Pentylene Glycol, Benzyl Salicylate, Citronellol, Hexyl Cinnamal, Hydroxycitronellal, Parfum
Sodium Lauroyl Methylaminopropionate
Cocamide Mea
Caprylyl Glycol
PPG-3 Myristyl Ether
Panthenol
Salicylic Acid
Menthol
Niacinamide
Pentasodium Pentetate
Gluconolactone
Aminomethyl Propanol
Biotin
Mentha Piperita Leaf Extract
Mentha Viridis Extract
Leonurus Sibiricus Flower/Leaf/Stem Extract
Nelumbo Nucifera Flower Extract
Houttuynia Cordata Extract
Artemisia Vulgaris Extract
Camellia Sinensis Leaf Extract
Mentha Rotundifolia Leaf Extract
Centella Asiatica Extract
Hexapeptide-9
Palmitoyl Pentapeptide-4
Palmitoyl Tripeptide-5
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Palmitoyl Oligopeptide
Tripeptide-1
Copper Tripeptide-1
Asiatic Acid
Asiaticoside
Acetyl Hexapeptide-8
Acetyl Tetrapeptide-2
Madecassic Acid
Madecassoside
Nonapeptide-1
Water, Cocamidopropyl Betaine, Tea-Cocoyl Glutamate, Sodium Lauroyl Methylaminopropionate, Disodium Laureth Sulfosuccinate, Cocamide Mea, Sodium Chloride, Parfum, Polyquaternium-10, Caprylyl Glycol, Hydroxyacetophenone, PPG-3 Myristyl Ether, Panthenol, Salicylic Acid, Menthol, Citric Acid, Niacinamide, Sodium Benzoate, Pentasodium Pentetate, Butylene Glycol, Gluconolactone, Aminomethyl Propanol, 1,2-Hexanediol, Biotin, Mentha Piperita Leaf Extract, Mentha Viridis Extract, Leonurus Sibiricus Flower/Leaf/Stem Extract, Nelumbo Nucifera Flower Extract, Houttuynia Cordata Extract, Artemisia Vulgaris Extract, Camellia Sinensis Leaf Extract, Mentha Rotundifolia Leaf Extract, Centella Asiatica Extract, Ethylhexylglycerin, Hydrolyzed Corn Protein, Hydrolyzed Soy Protein, Hydrolyzed Wheat Protein, Hexapeptide-9, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-5, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide, Tripeptide-1, Copper Tripeptide-1, Asiatic Acid, Asiaticoside, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-2, Madecassic Acid, Madecassoside, Nonapeptide-1
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Cocamidopropyl Betaine is a fatty acid created by mixing similar compounds in coconut oil and dimethylaminopropylamine, a compound with two amino groups.
This ingredient is a surfactant and cleanser. It helps gather the dirt, pollutants, and other impurities in your skin to be washed away. It also helps thicken a product and make the texture more creamy.
Being created from coconut oil means Cocamidopropyl Betaine is hydrating for the skin.
While Cocamidopropyl Betaine was believed to be an allergen, a study from 2012 disproved this. It found two compounds in unpure Cocamidopropyl Betaine to be the irritants: aminoamide and 3-dimethylaminopropylamine. High-grade and pure Cocamidopropyl Betaine did not induce allergic reactions during this study.
This ingredient is a cleansing agent, surfactant, and foam booster. It considered an alternative to traditional sulfates (Sulfosuccinate) and is allowed in "sulfate-free" products.
According to a manufacturer, this ingredient is mild and can be used in baby and bath options.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
We don't have a description for Hydrolyzed Corn Protein yet.
Hydrolyzed Soy Protein is a water-soluble blend of peptides and amino acids made by breaking down the protein from soybeans into smaller proteins.
It's the most widely used hydrolyzed vegetable protein in cosmetics and it acts mainly as a skin and hair conditioning agent.
The smaller fragments are water-loving so it forms a thin, moisture-retentive film on skin that helps reduce water loss and leaves things feeling softer and smoother.
You'll often see it credited with "firming" or "anti-aging" benefits as well; this claim traces back to lab research like Tokudome et al. (2012). This study added low-molecular-weight soybean peptides to cultured human skin fibroblasts and saw increased type I collagen gene expression + collagen content.
The caveat is that this is in-vitro and oral-peptide research so the only solid, well-established role for the topical ingredient is skin conditioning.
Typical use concentrations go up to 3.5% in mascara but this ingredient is typically used at low levels well under 1%.
It has a reassuring safety profile as well; it's not a skin irritant in testing up to 20% and has limited skin penetration due to its large size and water-loving nature.
Anyone with a known soy allergy should definitely patch test or skip this ingredient. There's also a single case of a soy-containing product aggravating rosacea via protein contact dermatitis, but this is very rare.
This ingredient is a plant-derived protein made by breaking down wheat proteins into smaller amino acids and peptides. It has skin and hair conditioning properties.
People with known wheat allergy or a history of immediate reactions should be cautious with leave-on products containing hydrolyzed wheat proteins.
Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Polyquaternium-10 is an ammonium salt of hydroxyethylcellulose. It is a white and granular powder used as a film-former and anti-static agent.
This ingredient is commonly found in hair conditioning products. According to a manufacturer, its positive charge makes it great for absorbing hair proteins. The manufacturer also states this ingredient helps with curl retention.
For haircare friends: this ingredient is not a silicone.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.
You might see this ingredient used in scrubs as a primary exfoliating ingredient.
We don't have a description for Tea-Cocoyl Glutamate yet.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!