Skin science article
Lancôme Advanced Génifique Night Cream Versus L'Oreal Revitalift 1.5% Pure Hyaluronic Acid Serum
Lancôme Advanced Génifique Night Cream Versus L'Oreal Revitalift 1.5% Pure Hyaluronic Acid Serum This barrier-repair night moisturizer is formulated around Bifida Ferment Lysate and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. Th
Lancôme Advanced Génifique Night Cream Versus L'Oreal Revitalift 1.5% Pure Hyaluronic Acid Serum
This barrier-repair night moisturizer is formulated around Bifida Ferment Lysate and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.
This hydrating serum is formulated around Sodium Hyaluronate and Dipeptide Diaminobutyroyl Benzylamide Diacetate to hydrate skin and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Bifida Ferment Lysate
Glycerin
Dicaprylyl Ether
Pentylene Glycol
Polyglyceryl-6 Distearate
Propanediol
Cetyl Esters
Jojoba Esters
Ammonium Polyacryloyldimethyl Taurate
Behenyl Alcohol
Octyldodecanol
Acacia Decurrens Flower Wax
Helianthus Annuus Seed Wax
Helianthus Annuus Seed Oil
Polymnia Sonchifolia Root Juice
Ceramide NP
Alpha-Glucan Oligosaccharide
Sodium Hyaluronate
Sodium Hydroxide
Sodium Stearoyl Glutamate
Salicyloyl Phytosphingosine
2-Oleamido-1,3-Octadecanediol
Adenosine
Mannose
Coco-Caprylate/Caprate
Ascorbyl Glucoside
Hydroxyacetophenone
Hydroxypalmitoyl Sphinganine
Hydroxypropyl Starch Phosphate
Capryloyl Salicylic Acid
Trisodium Ethylenediamine Disuccinate
Lactic Acid
Lactobacillus
Acetic Acid
Maltodextrin
Faex Extract
Polyglycerin-3
Polyglyceryl-3 Beeswax
Cetyl Alcohol
Tocopherol
Sodium Benzoate
Linalool
Limonene
Citronellol
Parfum
Water, Bifida Ferment Lysate, Glycerin, Dicaprylyl Ether, Pentylene Glycol, Polyglyceryl-6 Distearate, Propanediol, Cetyl Esters, Jojoba Esters, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Octyldodecanol, Acacia Decurrens Flower Wax, Helianthus Annuus Seed Wax, Helianthus Annuus Seed Oil, Polymnia Sonchifolia Root Juice, Ceramide NP, Alpha-Glucan Oligosaccharide, Sodium Hyaluronate, Sodium Hydroxide, Sodium Stearoyl Glutamate, Salicyloyl Phytosphingosine, 2-Oleamido-1,3-Octadecanediol, Adenosine, Mannose, Coco-Caprylate/Caprate, Ascorbyl Glucoside, Hydroxyacetophenone, Hydroxypalmitoyl Sphinganine, Hydroxypropyl Starch Phosphate, Capryloyl Salicylic Acid, Trisodium Ethylenediamine Disuccinate, Lactic Acid, Lactobacillus, Acetic Acid, Maltodextrin, Faex Extract, Polyglycerin-3, Polyglyceryl-3 Beeswax, Cetyl Alcohol, Tocopherol, Sodium Benzoate, Linalool, Limonene, Citronellol, Parfum
Hydroxyethylpiperazine Ethane Sulfonic Acid
PEG-60
Hydrogenated Castor Oil
Secale Cereale Seed Extract
Calcium Pantothenate
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Disodium EDTA
Phenoxyethanol
Chlorphenesin
Water, Glycerin, Hydroxyethylpiperazine Ethane Sulfonic Acid, Sodium Hyaluronate, PEG-60, Hydrogenated Castor Oil, Secale Cereale Seed Extract, Calcium Pantothenate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Ascorbyl Glucoside, Disodium EDTA, Pentylene Glycol, Phenoxyethanol, Chlorphenesin
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ascorbyl Glucoside (AA-2G) is one of the most stable vitamin C derivatives out there.
It's made by attaching a glucose molecule to ascorbic acid; this glucose "cap" shields the vitamin C from air, light, heat, and metal ions that normally cause pure ascorbic acid to oxidize.
Once on your skin, the enzyme alpha-glucosidase snips off the glucose and gradually releases active ascorbic acid right where it's needed. Basically, it behaves like a slow-release pro-vitamin C with less of a stinging that high-strength ascorbic acid can cause.
The research supports the classic vitamin C benefits as well. In lab and human studies, AA-2G slowed down the skin's production of melanin (the pigment behind dark spots) and helped shield skin cells against sun damage better than ascorbyl phosphate.
These studies also showed AA-2G released vitamin C over a longer period.
A frequently cited manufacturer trial found that a 2% AA-2G face cream significantly improved wrinkle depth and skin roughness after 45 days.
And in 2009, a clinical trial showed it meaningfully lightened dark patches on the gums compared to a placebo.
There's also collagen-synthesis support (since vitamin C is a required cofactor for that) and an antioxidant effect too.
Typical usage is usually between 0.5-5% and most studies/products land around 2%.
AA-2G performs best when formulated at a mildly acidic pH (~5-7) which is much gentler than the pH that pure vitamin C demands (~2.5-3.5).
Just one thing worth knowing: the in-skin conversation rate is only about 55-60% by weight. So a 5% AA-2G product delivers roughly 2.75-3% of actual active vitamin C. On top of that, skin absorption is relatively low because the ingredient is water-soluble.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!