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Lancôme Advanced Génifique Youth Activating Concentrate Versus Dr. Jart+ Peptidin™ Firming Serum With Energy Peptides

Lancôme Advanced Génifique Youth Activating Concentrate Versus Dr. Jart+ Peptidin™ Firming Serum With Energy Peptides This anti-aging serum is formulated around Bifida Ferment Lysate and Ascorbyl Glucoside to soften the look of wrinkles and strengthen the skin

Lancôme Advanced Génifique Youth Activating Concentrate Versus Dr. Jart+ Peptidin™ Firming Serum With Energy Peptides

This anti-aging serum is formulated around Bifida Ferment Lysate and Ascorbyl Glucoside to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Bifida Ferment Lysate

Glycerin

Alcohol Denat.

Dimethicone

Hydroxyethylpiperazine Ethane Sulfonic Acid

Ascorbyl Glucoside

Sodium Hyaluronate

Sodium Hydroxide

Sodium Benzoate

Phenoxyethanol

Adenosine

Yeast Extract

PEG-20 Methyl Glucose Sesquistearate

PEG-60 Hydrogenated Castor Oil

Salicyloyl Phytosphingosine

Ammonium Polyacryloyldimethyl Taurate

Limonene

Xanthan Gum

Caprylyl Glycol

Disodium EDTA

Octyldodecanol

Citronellol

Parfum

Water, Bifida Ferment Lysate, Glycerin, Alcohol Denat., Dimethicone, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ascorbyl Glucoside, Sodium Hyaluronate, Sodium Hydroxide, Sodium Benzoate, Phenoxyethanol, Adenosine, Yeast Extract, PEG-20 Methyl Glucose Sesquistearate, PEG-60 Hydrogenated Castor Oil, Salicyloyl Phytosphingosine, Ammonium Polyacryloyldimethyl Taurate, Limonene, Xanthan Gum, Caprylyl Glycol, Disodium EDTA, Octyldodecanol, Citronellol, Parfum

Methylpropanediol

1,2-Hexanediol

Caprylic/Capric Triglyceride

Niacinamide

Polyglycerin-3

Borago Officinalis Extract

Algae Extract

Eclipta Prostrata Leaf Extract

Cyclohexasiloxane

Centaurea Cyanus Flower Water

Melia Azadirachta Leaf Extract

Melia Azadirachta Flower Extract

Avena Sativa Kernel Extract

Cynara Scolymus Leaf Extract

Pteris Multifida Extract

Coccinia Indica Fruit Extract

Aloe Barbadensis Flower Extract

Solanum Melongena Fruit Extract

Ocimum Sanctum Leaf Extract

Nymphaea Alba Flower Extract

Corallina Officinalis Extract

Curcuma Longa Root Extract

Nymphaea Caerulea Flower Water

Ethylhexylglycerin

Fructooligosaccharides

Hydrogenated Lecithin

Citrus Aurantium Bergamia Fruit Oil

Beta-Glucan

Polyquaternium-51

Butylene Glycol

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Carbomer

Tromethamine

Inositol

Propanediol

Hydrolyzed Hyaluronic Acid

Dipropylene Glycol

Sodium Palmitoyl Proline

Lavandula Angustifolia Oil

Cholesterol

Cyanocobalamin

Glycine

Acetyl Glutamine

Dipalmitoyl Hydroxyproline

Sodium Cocoyl Alaninate

Serine

Glutamic Acid

Aspartic Acid

Leucine

Alanine

Lysine

Arginine

Tyrosine

Phenylalanine

Proline

Threonine

Valine

Isoleucine

Histidine

Cysteine

Methionine

Acetyl Hexapeptide-8

Copper Tripeptide-1

Hexapeptide-9

Nonapeptide-1

Palmitoyl Pentapeptide-4

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Tripeptide-1

Water, Methylpropanediol, Glycerin, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Niacinamide, Polyglycerin-3, Borago Officinalis Extract, Algae Extract, Eclipta Prostrata Leaf Extract, Cyclohexasiloxane, Centaurea Cyanus Flower Water, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Avena Sativa Kernel Extract, Cynara Scolymus Leaf Extract, Pteris Multifida Extract, Coccinia Indica Fruit Extract, Aloe Barbadensis Flower Extract, Solanum Melongena Fruit Extract, Ocimum Sanctum Leaf Extract, Nymphaea Alba Flower Extract, Corallina Officinalis Extract, Curcuma Longa Root Extract, Nymphaea Caerulea Flower Water, Ethylhexylglycerin, Adenosine, Fructooligosaccharides, Hydrogenated Lecithin, Citrus Aurantium Bergamia Fruit Oil, Beta-Glucan, Disodium EDTA, Polyquaternium-51, Sodium Hyaluronate, Butylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Xanthan Gum, Carbomer, Tromethamine, Inositol, Propanediol, Hydrolyzed Hyaluronic Acid, Dipropylene Glycol, Sodium Palmitoyl Proline, Lavandula Angustifolia Oil, Cholesterol, Caprylyl Glycol, Cyanocobalamin, Glycine, Acetyl Glutamine, Dipalmitoyl Hydroxyproline, Sodium Cocoyl Alaninate, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Histidine, Cysteine, Methionine, Acetyl Hexapeptide-8, Copper Tripeptide-1, Hexapeptide-9, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Tripeptide-1

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
  10. 10Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
  11. 11Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
  12. 12Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
  13. 13The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure …
  14. 14Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
  15. 15Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  16. 16Topically, glycerin does several things at once:
  17. 17Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  18. 18Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  19. 19This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  20. 20Just know very high concentrations (>40%) can feel tacky in low humidity.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

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