Skin science article
Lancôme Advanced Génifique Youth Activating Concentrate Versus Dr. Jart+ Peptidin™ Firming Serum With Energy Peptides
Lancôme Advanced Génifique Youth Activating Concentrate Versus Dr. Jart+ Peptidin™ Firming Serum With Energy Peptides This anti-aging serum is formulated around Bifida Ferment Lysate and Ascorbyl Glucoside to soften the look of wrinkles and strengthen the skin
Lancôme Advanced Génifique Youth Activating Concentrate Versus Dr. Jart+ Peptidin™ Firming Serum With Energy Peptides
This anti-aging serum is formulated around Bifida Ferment Lysate and Ascorbyl Glucoside to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Bifida Ferment Lysate
Glycerin
Alcohol Denat.
Dimethicone
Hydroxyethylpiperazine Ethane Sulfonic Acid
Ascorbyl Glucoside
Sodium Hyaluronate
Sodium Hydroxide
Sodium Benzoate
Phenoxyethanol
Adenosine
Yeast Extract
PEG-20 Methyl Glucose Sesquistearate
PEG-60 Hydrogenated Castor Oil
Salicyloyl Phytosphingosine
Ammonium Polyacryloyldimethyl Taurate
Limonene
Xanthan Gum
Caprylyl Glycol
Disodium EDTA
Octyldodecanol
Citronellol
Parfum
Water, Bifida Ferment Lysate, Glycerin, Alcohol Denat., Dimethicone, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ascorbyl Glucoside, Sodium Hyaluronate, Sodium Hydroxide, Sodium Benzoate, Phenoxyethanol, Adenosine, Yeast Extract, PEG-20 Methyl Glucose Sesquistearate, PEG-60 Hydrogenated Castor Oil, Salicyloyl Phytosphingosine, Ammonium Polyacryloyldimethyl Taurate, Limonene, Xanthan Gum, Caprylyl Glycol, Disodium EDTA, Octyldodecanol, Citronellol, Parfum
Methylpropanediol
1,2-Hexanediol
Caprylic/Capric Triglyceride
Niacinamide
Polyglycerin-3
Borago Officinalis Extract
Algae Extract
Eclipta Prostrata Leaf Extract
Cyclohexasiloxane
Centaurea Cyanus Flower Water
Melia Azadirachta Leaf Extract
Melia Azadirachta Flower Extract
Avena Sativa Kernel Extract
Cynara Scolymus Leaf Extract
Pteris Multifida Extract
Coccinia Indica Fruit Extract
Aloe Barbadensis Flower Extract
Solanum Melongena Fruit Extract
Ocimum Sanctum Leaf Extract
Nymphaea Alba Flower Extract
Corallina Officinalis Extract
Curcuma Longa Root Extract
Nymphaea Caerulea Flower Water
Ethylhexylglycerin
Fructooligosaccharides
Hydrogenated Lecithin
Citrus Aurantium Bergamia Fruit Oil
Beta-Glucan
Polyquaternium-51
Butylene Glycol
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Carbomer
Tromethamine
Inositol
Propanediol
Hydrolyzed Hyaluronic Acid
Dipropylene Glycol
Sodium Palmitoyl Proline
Lavandula Angustifolia Oil
Cholesterol
Cyanocobalamin
Glycine
Acetyl Glutamine
Dipalmitoyl Hydroxyproline
Sodium Cocoyl Alaninate
Serine
Glutamic Acid
Aspartic Acid
Leucine
Alanine
Lysine
Arginine
Tyrosine
Phenylalanine
Proline
Threonine
Valine
Isoleucine
Histidine
Cysteine
Methionine
Acetyl Hexapeptide-8
Copper Tripeptide-1
Hexapeptide-9
Nonapeptide-1
Palmitoyl Pentapeptide-4
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Tripeptide-1
Water, Methylpropanediol, Glycerin, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Niacinamide, Polyglycerin-3, Borago Officinalis Extract, Algae Extract, Eclipta Prostrata Leaf Extract, Cyclohexasiloxane, Centaurea Cyanus Flower Water, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Avena Sativa Kernel Extract, Cynara Scolymus Leaf Extract, Pteris Multifida Extract, Coccinia Indica Fruit Extract, Aloe Barbadensis Flower Extract, Solanum Melongena Fruit Extract, Ocimum Sanctum Leaf Extract, Nymphaea Alba Flower Extract, Corallina Officinalis Extract, Curcuma Longa Root Extract, Nymphaea Caerulea Flower Water, Ethylhexylglycerin, Adenosine, Fructooligosaccharides, Hydrogenated Lecithin, Citrus Aurantium Bergamia Fruit Oil, Beta-Glucan, Disodium EDTA, Polyquaternium-51, Sodium Hyaluronate, Butylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Xanthan Gum, Carbomer, Tromethamine, Inositol, Propanediol, Hydrolyzed Hyaluronic Acid, Dipropylene Glycol, Sodium Palmitoyl Proline, Lavandula Angustifolia Oil, Cholesterol, Caprylyl Glycol, Cyanocobalamin, Glycine, Acetyl Glutamine, Dipalmitoyl Hydroxyproline, Sodium Cocoyl Alaninate, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Histidine, Cysteine, Methionine, Acetyl Hexapeptide-8, Copper Tripeptide-1, Hexapeptide-9, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Tripeptide-1
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.