Lancôme Renergie Multi-lift Ultra Full Spectrum Anti-ageing Cream Versus Olay Regenerist Collagen Peptide 24 Moisturizer (Fragrance Free)

Lancôme Renergie Multi-lift Ultra Full Spectrum Anti-ageing Cream Versus Olay Regenerist Collagen Peptide 24 Moisturizer (Fragrance Free)

This anti-aging treatment is formulated around 3-O-Ethyl Ascorbic Acid and Adenosine to soften the look of wrinkles and brighten dull-looking skin.

This anti-aging moisturizer is formulated around Niacinamide and Panthenol to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dimethicone

Butyrospermum Parkii Butter

Octyldodecanol

Butylene Glycol

Cetyl Alcohol

PEG-100 Stearate

Glyceryl Stearate

3-O-Ethyl Ascorbic Acid

Tocopheryl Acetate

C13-14 Isoparaffin

Guanosine

Cyathea Medullaris Leaf Extract

Vaccinium Myrtillus Fruit Extract

Saccharum Officinarum Extract

Hydroxypropyl Tetrahydropyrantriol

Sodium Citrate

Hydrolyzed Linseed Extract

Hydrolyzed Lupine Protein

Sodium Benzoate

Sodium Levulinate

Stearic Acid

Phenoxyethanol

Phenylethyl Resorcinol

Adenosine

Acer Saccharum Extract

Palmitic Acid

Polyacrylamide

Chlorphenesin

Poloxamer 338

Limonene

Xanthan Gum

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Benzyl Alcohol

Cinnamic Acid

Propylene Glycol

2-Oleamido-1,3-Octadecanediol

Leontopodium Alpinum Extract

Biosaccharide Gum-1

Alpha-Isomethyl Ionone

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Myristic Acid

Geraniol

Disodium EDTA

Citric Acid

Potassium Hydroxide

Citrus Aurantium Dulcis Fruit Extract

Citrus Limon Fruit Extract

Potassium Sorbate

BHT

Laureth-7

Levulinic Acid

Hexyl Cinnamal

Glyceryl Caprylate

Parfum

Water, Glycerin, Dimethicone, Butyrospermum Parkii Butter, Octyldodecanol, Butylene Glycol, Cetyl Alcohol, PEG-100 Stearate, Glyceryl Stearate, 3-O-Ethyl Ascorbic Acid, Tocopheryl Acetate, C13-14 Isoparaffin, Guanosine, Cyathea Medullaris Leaf Extract, Vaccinium Myrtillus Fruit Extract, Saccharum Officinarum Extract, Hydroxypropyl Tetrahydropyrantriol, Sodium Citrate, Hydrolyzed Linseed Extract, Hydrolyzed Lupine Protein, Sodium Benzoate, Sodium Levulinate, Stearic Acid, Phenoxyethanol, Phenylethyl Resorcinol, Adenosine, Acer Saccharum Extract, Palmitic Acid, Polyacrylamide, Chlorphenesin, Poloxamer 338, Limonene, Xanthan Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Benzyl Alcohol, Cinnamic Acid, Propylene Glycol, 2-Oleamido-1,3-Octadecanediol, Leontopodium Alpinum Extract, Biosaccharide Gum-1, Alpha-Isomethyl Ionone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Myristic Acid, Geraniol, Disodium EDTA, Citric Acid, Potassium Hydroxide, Citrus Aurantium Dulcis Fruit Extract, Citrus Limon Fruit Extract, Potassium Sorbate, BHT, Laureth-7, Levulinic Acid, Hexyl Cinnamal, Glyceryl Caprylate, Parfum

Niacinamide

Isohexadecane

Isopropyl Isostearate

Stearyl Alcohol

Panthenol

Palmitoyl Pentapeptide-4

Tremella Fuciformis Sporocarp Extract

Tapioca Starch

Caprylyl Glycol

Dimethiconol

Cetearyl Alcohol

Cetearyl Glucoside

Behenyl Alcohol

Titanium Dioxide

Polymethylsilsesquioxane

1,2-Hexanediol

Water, Glycerin, Niacinamide, Isohexadecane, Dimethicone, Isopropyl Isostearate, Stearyl Alcohol, Polyacrylamide, Panthenol, Palmitoyl Pentapeptide-4, Tremella Fuciformis Sporocarp Extract, Tapioca Starch, C13-14 Isoparaffin, Caprylyl Glycol, Dimethiconol, Laureth-7, Cetearyl Alcohol, Cetearyl Glucoside, Palmitic Acid, Stearic Acid, Cetyl Alcohol, Behenyl Alcohol, Disodium EDTA, PEG-100 Stearate, Titanium Dioxide, Polymethylsilsesquioxane, 1,2-Hexanediol, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

C13-14 Isoparaffin is a synthetic emollient, solvent, and thickening agent. It helps soften skin and improves spreadability without leaving a greasy residue.

This ingredient has been found to be non-sensitizing and safe for use in cosmetics.

Two things floating around online that cause fear-mongering:

There's one scary-sounding study related to kidney tumors in male rats; this depends on a protein called alpha-2u-globulin that binds the ingredient and clogs up kidney cells. Female rats barely make this protein, and humans don't make it at all so this effect cannot happen to us. Regulatory bodies have states this rat-only pathway shouldn't be used to judge human risk.

The other thing you'll see is 1,4-dioxane being a trace byproduct that can form during manufacturing of petroleum-derived ingredients. This is a real, but heavily managed/monitored issue. This byproduct is removed through purification steps before the ingredients goes into the formula. Regulatory bodies also actively monitor residual levels for safety.

One last thing to note: this ingredient is a pure hydrocarbon with no fatty-acid or ester chains for Malassezia to feed on, so it's considered fungal acne safe.

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

This ingredient is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.

Palmitic Acid is a fatty acid naturally found in our skin and in many plant and animal sources.

In cosmetics, it is usually derived from palm oil. It serves many purposes in skincare, acting as a cleanser, emollient, and emulsifier.

Interestingly, topically applied Palmitic Acid can be elongated into longer chain fatty acids and ceramides. A 2019 study found low levels of Palmitic Acid lead to slower development of cells, suggesting it plays a role in keeping your skin's renewal process on track.

The CIR (Cosmetic Ingredient Review) panel determined it safe as used in cosmetics at concentrations up to 13%. It is non-irritating and non-sensitizing in clinical studies.

The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Palmitic Acid, at C16, falls right into that sweet spot.

In vitro studies have shown that Palmitic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.

It's worth noting that what feeds yeast in a lab doesn't necessarily feed it on your face since formulation and your skin's chemistry play a bigger role.

Peg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.

PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.

It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.

We recommend speaking with a professional if you have concerns.

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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