LEO Pharma Azalea Cream Versus Dpharm - Dong A Pharmaceutical Acnon Cream

LEO Pharma Azalea Cream Versus Dpharm - Dong A Pharmaceutical Acnon Cream

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Azelaic Acid

Benzoic Acid

Glycerin 85%

Cetearyl Ethylhexanoate

Allantoin

Water

Glyceryl Stearate

Cetearyl Alcohol

Cetyl Palmitate

Cocoglycerides

Propylene Glycol

Azelaic Acid, Benzoic Acid, Glycerin 85%, Cetearyl Ethylhexanoate, Allantoin, Water, Glyceryl Stearate, Cetearyl Alcohol, Cetyl Palmitate, Cocoglycerides, Propylene Glycol

Ibuprofen Piconol

O-Cymen-5-Ol

Methylparaben

Propylparaben

Dimethicone

Isopropyl Myristate

Petrolatum

Butylene Glycol

BHT

Tetrasodium EDTA

PEG-40 Stearate

Ibuprofen Piconol, O-Cymen-5-Ol, Methylparaben, Propylparaben, Glyceryl Stearate, Dimethicone, Isopropyl Myristate, Petrolatum, Butylene Glycol, BHT, Cetearyl Alcohol, Tetrasodium EDTA, Water, PEG-40 Stearate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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