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Skin science article

Logically Skin Brightuning Peptide Ampoule Versus Isntree TW-Real Bifida Ampoule

Logically Skin Brightuning Peptide Ampoule Versus Isntree TW-Real Bifida Ampoule This brightening ampoule is formulated around Saccharomyces/Rice Ferment Filtrate and Niacinamide to brighten dull-looking skin and soften the look of wrinkles. This barrier-repai

Logically Skin Brightuning Peptide Ampoule Versus Isntree TW-Real Bifida Ampoule

This brightening ampoule is formulated around Saccharomyces/Rice Ferment Filtrate and Niacinamide to brighten dull-looking skin and soften the look of wrinkles.

This barrier-repair ampoule is formulated around Bifida Ferment Lysate and Niacinamide to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Saccharomyces/Rice Ferment Filtrate

Water

Isopropyl Myristate

Glycerin

Niacinamide

Methylpropanediol

1,2-Hexanediol

Butylene Glycol

Sodium Polyacryloyldimethyl Taurate

Dipropylene Glycol

Hydroxyacetophenone

Hydrogenated Polydecene

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Caprylyl Glycol

Glyceryl Glucoside

Tromethamine

Trideceth-10

Disodium EDTA

Heptasodium Hexacarboxymethyl Dipeptide-12

Pentasodium Tetracarboxymethyl Acetylhydroxyprolyl Dipeptide-12

Melia Azadirachta Flower Extract

Ocimum Sanctum Leaf Extract

Betaine

Melia Azadirachta Leaf Extract

Pentasodium Tetracarboxymethyl Dipeptide-51

Curcuma Longa Root Extract

Dipeptide-1

Corallina Officinalis Extract

Dipotassium Glycyrrhizate

Ananas Sativus Fruit Extract

Pentylene Glycol

Madecassoside

Saccharomyces/Rice Ferment Filtrate, Water, Isopropyl Myristate, Glycerin, Niacinamide, Methylpropanediol, 1,2-Hexanediol, Butylene Glycol, Sodium Polyacryloyldimethyl Taurate, Dipropylene Glycol, Hydroxyacetophenone, Hydrogenated Polydecene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Glyceryl Glucoside, Tromethamine, Trideceth-10, Disodium EDTA, Heptasodium Hexacarboxymethyl Dipeptide-12, Pentasodium Tetracarboxymethyl Acetylhydroxyprolyl Dipeptide-12, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Betaine, Melia Azadirachta Leaf Extract, Pentasodium Tetracarboxymethyl Dipeptide-51, Curcuma Longa Root Extract, Dipeptide-1, Corallina Officinalis Extract, Dipotassium Glycyrrhizate, Ananas Sativus Fruit Extract, Pentylene Glycol, Madecassoside

Bifida Ferment Lysate

Lactobacillus/Pumpkin Ferment Extract

Lactobacillus/Soybean Ferment Extract

Rice Ferment Filtrate

Sodium Hyaluronate

Hydrolyzed Collagen

Salix Alba Bark Extract

Origanum Vulgare Leaf Extract

Cinnamomum Zeylanicum Bark Extract

Portulaca Oleracea Extract

Chamaecyparis Obtusa Leaf Extract

Beta-Glucan

Palmitoyl Oligopeptide

Copper Tripeptide-1

Acetyl Hexapeptide-8

Allantoin

Hydroxyethylcellulose

Panthenol

Carbomer

Arginine

Scutellaria Baicalensis Root Extract

Illicium Verum Fruit Extract

Adenosine

Bifida Ferment Lysate, Dipropylene Glycol, Niacinamide, Glycerin, Lactobacillus/Pumpkin Ferment Extract, Lactobacillus/Soybean Ferment Extract, Rice Ferment Filtrate, Sodium Hyaluronate, Hydrolyzed Collagen, Salix Alba Bark Extract, Origanum Vulgare Leaf Extract, Cinnamomum Zeylanicum Bark Extract, Portulaca Oleracea Extract, Chamaecyparis Obtusa Leaf Extract, Beta-Glucan, Palmitoyl Oligopeptide, Copper Tripeptide-1, Acetyl Hexapeptide-8, Allantoin, Hydroxyethylcellulose, Panthenol, Carbomer, Arginine, Butylene Glycol, Scutellaria Baicalensis Root Extract, Illicium Verum Fruit Extract, Adenosine, 1,2-Hexanediol, Disodium EDTA

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

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Formula cabinet

Ingredients & structured notes

02

Product index

Related product references

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Comparison edit

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