Skin science article
Mad Hippie Corrective Peptide Serum Versus Paula's Choice Pro-Collagen Multi-Peptide Booster
Mad Hippie Corrective Peptide Serum Versus Paula's Choice Pro-Collagen Multi-Peptide Booster This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Ceramide NP to soften the look of wrinkles and strengthen the skin barrier. What's inside Key In
Mad Hippie Corrective Peptide Serum Versus Paula's Choice Pro-Collagen Multi-Peptide Booster
This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Ceramide NP to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Caprylic/Capric Triglyceride
Chenopodium Quinoa Seed Extract
Propanediol
Potassium Cetyl Phosphate
Acetyl Tetrapeptide-2
Sodium Hyaluronate
Apium Graveolens Seed Extract
Linum Usitatissimum Seed Extract
Hydroxypropyl Cyclodextrin
Palmitoyl Tripeptide-38
Tremella Fuciformis Polysaccharide
Squalane
Hydrolyzed Yeast Extract
Sorbitan Trioleate
Cetyl Hydroxyethylcellulose
Polyglucuronic Acid
Acetyl Tetrapeptide-22
Avena Sativa Meal Extract
Phenethyl Alcohol
Caprylyl Glycol
Ethylhexylglycerin
Stearyl Alcohol
Polyglutamic Acid
Hydroxyethylcellulose
Citrus Aurantium Dulcis Peel Oil
Lecithin
Ceramide NP
Tocopherol
Water, Glycerin, Caprylic/Capric Triglyceride, Chenopodium Quinoa Seed Extract, Propanediol, Potassium Cetyl Phosphate, Acetyl Tetrapeptide-2, Sodium Hyaluronate, Apium Graveolens Seed Extract, Linum Usitatissimum Seed Extract, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38, Tremella Fuciformis Polysaccharide, Squalane, Hydrolyzed Yeast Extract, Sorbitan Trioleate, Cetyl Hydroxyethylcellulose, Polyglucuronic Acid, Acetyl Tetrapeptide-22, Avena Sativa Meal Extract, Phenethyl Alcohol, Caprylyl Glycol, Ethylhexylglycerin, Stearyl Alcohol, Polyglutamic Acid, Hydroxyethylcellulose, Citrus Aurantium Dulcis Peel Oil, Lecithin, Ceramide NP, Tocopherol
Pentylene Glycol
Pyrus Malus Fruit Extract
Dimethicone
Ceramide AP
1,2-Hexanediol
Glyceryl Glucoside
Palmitoyl Tetrapeptide-72 Amide
Sh-Polypeptide-121
Tridecapeptide-1
C9-12 Alkane
Ammonium Polyacryloyldimethyl Taurate
Polygonum Bistorta Root Extract
Bacillus Ferment
Sodium Phytate
Coco-Caprylate/Caprate
Hexylene Glycol
Xanthan Gum
Magnesium Chloride
Potassium Sorbate
Sodium Benzoate
Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, Ceramide AP, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tetrapeptide-72 Amide, Sh-Polypeptide-121, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, C9-12 Alkane, Ammonium Polyacryloyldimethyl Taurate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Sodium Phytate, Coco-Caprylate/Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
We don't have a description for Cetyl Hydroxyethylcellulose yet.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
We don't have a description for Hydrolyzed Yeast Extract yet.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
We don't have a description for Polyglucuronic Acid yet.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!