Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Maelove Moonlight Retinal Super Serum Versus Allies of Skin Retinal & Peptides Repair Night Cream

Maelove Moonlight Retinal Super Serum Versus Allies of Skin Retinal & Peptides Repair Night Cream This anti-aging serum is formulated around Aloe Barbadensis Leaf Juice and Niacinamide to soften the look of wrinkles and refine skin texture. This anti-aging nig

Maelove Moonlight Retinal Super Serum Versus Allies of Skin Retinal & Peptides Repair Night Cream

This anti-aging serum is formulated around Aloe Barbadensis Leaf Juice and Niacinamide to soften the look of wrinkles and refine skin texture.

This anti-aging night moisturizer is formulated around Palmitoyl Tetrapeptide-7 and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Aloe Barbadensis Leaf Juice

Water

Niacinamide

Cyclodextrin

Glycerin

Caprylic/Capric Triglyceride

Gluconolactone

Squalane

Bisabolol

Ceramide NP

Michelia Alba Flower Oil

Hamamelis Virginiana Water

Camellia Oleifera Leaf Extract

Rubus Chamaemorus Seed Oil

Sodium Hyaluronate

Tocopheryl Acetate

Vaccinium Macrocarpon Fruit Extract

Retinal

Polygonum Cuspidatum Extract

Pentylene Glycol

Maltodextrin

Lonicera Japonica Flower Extract

Lonicera Caprifolium Flower Extract

Xanthan Gum

Sodium Benzoate

Sodium Gluconate

Polysorbate 20

Citrus Grandis Peel Oil

Citrus Aurantium Dulcis Peel Oil

Citrus Aurantium Bergamia Fruit Oil

Alcohol

Alcohol Denat.

Aloe Barbadensis Leaf Juice, Water, Niacinamide, Cyclodextrin, Glycerin, Caprylic/Capric Triglyceride, Gluconolactone, Squalane, Bisabolol, Ceramide NP, Michelia Alba Flower Oil, Hamamelis Virginiana Water, Camellia Oleifera Leaf Extract, Rubus Chamaemorus Seed Oil, Sodium Hyaluronate, Tocopheryl Acetate, Vaccinium Macrocarpon Fruit Extract, Retinal, Polygonum Cuspidatum Extract, Pentylene Glycol, Maltodextrin, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Xanthan Gum, Sodium Benzoate, Sodium Gluconate, Polysorbate 20, Citrus Grandis Peel Oil, Citrus Aurantium Dulcis Peel Oil, Citrus Aurantium Bergamia Fruit Oil, Alcohol, Alcohol Denat.

Propanediol

Argania Spinosa Kernel Oil

Sodium Acrylates Copolymer

Hydrolyzed Candida Saitoana Extract

Sodium Stearoyl Glutamate

Albizia Julibrissin Bark Extract

Dimethyl Isosorbide

Galactoarabinan

Palmitoyl Tetrapeptide-7

Palmitoyl Oligopeptide

Caprooyl Tetrapeptide-3

Cassia Angustifolia Seed Polysaccharide

Hyaluronic Acid

Oxycoccus Palustris Seed Oil

Withania Somnifera Root Extract

Citrus Aurantium Dulcis Callus Culture Extract

Ellagic Acid

Phenyl T-Butylnitrone

Ergothioneine

Glutathione

Mirabilis Jalapa Flower/Leaf/Stem Extract

N-Hydroxysuccinimide

Chrysin

Glutamylamidoethyl Imidazole

Lavandula Hybrida Oil

Butylene Glycol

Caprylyl Glycol

Steareth-20

Citric Acid

Dextran

Acetyl Tributyl Citrate

Potassium Sorbate

Phenoxyethanol

Geraniol

Limonene

Linalool

Water, Glycerin, Caprylic/Capric Triglyceride, Propanediol, Argania Spinosa Kernel Oil, Sodium Acrylates Copolymer, Hydrolyzed Candida Saitoana Extract, Sodium Stearoyl Glutamate, Albizia Julibrissin Bark Extract, Dimethyl Isosorbide, Galactoarabinan, Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide, Caprooyl Tetrapeptide-3, Cassia Angustifolia Seed Polysaccharide, Hyaluronic Acid, Oxycoccus Palustris Seed Oil, Rubus Chamaemorus Seed Oil, Niacinamide, Withania Somnifera Root Extract, Citrus Aurantium Dulcis Callus Culture Extract, Retinal, Ellagic Acid, Phenyl T-Butylnitrone, Ergothioneine, Glutathione, Mirabilis Jalapa Flower/Leaf/Stem Extract, N-Hydroxysuccinimide, Chrysin, Glutamylamidoethyl Imidazole, Lonicera Caprifolium Flower Extract, Lonicera Japonica Flower Extract, Lavandula Hybrida Oil, Pentylene Glycol, Butylene Glycol, Cyclodextrin, Caprylyl Glycol, Steareth-20, Citric Acid, Xanthan Gum, Dextran, Acetyl Tributyl Citrate, Potassium Sorbate, Phenoxyethanol, Geraniol, Limonene, Linalool

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Cyclodextrins are ring-shaped sugar molecules made from starch. It is used to stabilize, protect, and slowly release active ingredients.

This ingredient can help prevent oxidation, reduce irritation from strong actives, and make certain ingredients absorb better once applied.

Once applied to your skin, enzymes gradually break down the cyclodextrin "ring"; this releases the active ingredient in a controlled way.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

This Honeysuckle flower extract comes from the Italian honeysuckle. It is an antioxidant, antimicrobial, and fragrance.

Both this and the Japanese Honeysuckle are rich in a natural paraben that give it antimicrobial property. They are effective in inhibiting bacteria, yeast, and mold.

Honeysuckle contains flavonoids and saponins. Both of these components are natural antioxidants that can help soothe the skin.

As most flowers do, honeysuckle has a natural fragrance.

Lonicera Japonica Flower Extract comes from the honeysuckle flower.

Honeysuckles have skin protecting, anti-viral, and anti-inflammatory properties. It contains many antioxidants, such as luteolin, caffeic acid, loniflavone, and chlorogenic acids.

This honeysuckle is native to East Asia and used in traditional Chinese medicine to treat fever and inflammation.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Retinal (aka retinaldehyde) is a form of retinoid that formulators use mainly as an antiaging and skin-renewing active.

What makes it special is its position in the retinoid family; skin converts it to retinoic acid (the prescription gold standard) in just one step.

Because retinal only requires 1 conversion step to become retinoic acid, it's the strongest over-the-counter retinoid. It also works at lower concentrations than retinol, since retinal is about 10x more bioavailable.

Studies back up its efficacy in skin:

A foundational trial showed that applying 0.05-0.5% retinal for 1-3 months produced a dose-dependent and significant increase in epidermal thickness + cell turnover markers.

And a head-to-head comparison of 0.05% retinal against a 0.05% retinoid acid found both formulations were effective for the basis of wrinkle/skin roughness features, but retinoic acid caused more local irritation.

More recent controlled trials confirm it improves wrinkles, dermal density, and firmness over 12-24 weeks, with significant improvements in skin texture and firmness (particularly with the higher 0.1% concentration).

Retinal also has one trick the other retinoids do not: it directly fights against acne bacteria since a clinical study showed retinaldehyde-treated areas displayed a significant decrease in counts of viable P. acnes.

This makes it a great pick for people who want to treat aging and breakouts.

Typical cosmetic use sits in the 0.05-0.1% range with 0.05% being the gentle starting point and 0.1% giving stronger results.

Like all retinoids, retinal works best with nightly use, a good moisturizer, and daytime sunscreen. It can cause some irritation so ease into it slowly rather than going all in.

The "ramp up" method works well: start with Retinal once a week to give your skin time to adjust, which keeps irritation low.

Slowly add more nights until you reach your goal frequency once your skin feels comfortable.

Retinoids also make your skin more sensitive to the sun in the first few weeks, so wear sunscreen every morning and protect your skin from direct sun while you build up tolerance.

Cloudberry seed oil is rich in vitamin C, citric acid, malic acid, vitamin C, and beta-carotene.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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