Skin science article
maru.derm Anti-Blemish Skin Brightening Cream Versus Beauty of Joseon Red Bean Water Gel
maru.derm Anti-Blemish Skin Brightening Cream Versus Beauty of Joseon Red Bean Water Gel This brightening moisturizer is formulated around Niacinamide and Glycyrrhiza Glabra Root Extract to fade the look of dark spots and brighten dull-looking skin. This calmi
maru.derm Anti-Blemish Skin Brightening Cream Versus Beauty of Joseon Red Bean Water Gel
This brightening moisturizer is formulated around Niacinamide and Glycyrrhiza Glabra Root Extract to fade the look of dark spots and brighten dull-looking skin.
This calming moisturizer is formulated around Panthenol and Allantoin to calm redness and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Niacinamide
Glycerin
Glycyrrhiza Glabra Root Extract
Butyrospermum Parkii Butter
Allantoin
Solidago Virgaurea Extract
Panthenol
Alpha-Arbutin
Palmitoyl Sh-Octapeptide-24 Amide
Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1
Arginine
Aspartic Acid
Glycine
Alanine
Serine
Valine
Proline
Threonine
Isoleucine
Histidine
Phenylalanine
Phenoxyethanol
Caprylic/Capric Triglyceride
Xanthan Gum
Lactic Acid/Glycolic Acid Copolymer
Polyvinyl Alcohol
Caprylyl Glycol
Ethylhexylglycerin
Potassium Cetyl Phosphate
Tridecyl Salicylate
Tocopheryl Acetate
Carbomer
Dimethicone
Sodium PCA
Phenylpropanol
Glyceryl Caprylate
Water, Niacinamide, Glycerin, Glycyrrhiza Glabra Root Extract, Butyrospermum Parkii Butter, Allantoin, Solidago Virgaurea Extract, Panthenol, Alpha-Arbutin, Palmitoyl Sh-Octapeptide-24 Amide, Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1, Arginine, Aspartic Acid, Glycine, Alanine, Serine, Valine, Proline, Threonine, Isoleucine, Histidine, Phenylalanine, Phenoxyethanol, Caprylic/Capric Triglyceride, Xanthan Gum, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Caprylyl Glycol, Ethylhexylglycerin, Potassium Cetyl Phosphate, Tridecyl Salicylate, Tocopheryl Acetate, Carbomer, Dimethicone, Sodium PCA, Phenylpropanol, Glyceryl Caprylate
Butylene Glycol
1,2-Hexanediol
Methyl Trimethicone
Phaseolus Angularis Seed Extract
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Tromethamine
Glyceryl Glucoside
C12-14 Alketh-12
Maltodextrin
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Dimethicone/Vinyl Dimethicone Crosspolymer
Dimethicone Crosspolymer
Betaine
Dipotassium Glycyrrhizate
Polyquaternium-51
Disodium EDTA
Glyceryl Acrylate/Acrylic Acid Copolymer
Dioscorea Japonica Root Extract
Glucose
Sodium Citrate
Beta-Glucan
Hydrolyzed Corn Starch
Citric Acid
Sucrose
Magnesium Ascorbyl Phosphate
Helianthus Annuus Seed Oil
Tocopherol
Cyanocobalamin
Glutamic Acid
Leucine
Acetyl Hexapeptide-8
Lysine
Tyrosine
Cysteine
Methionine
Phosphoric Acid
Ascorbic Acid
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Water, Butylene Glycol, Glycerin, 1,2-Hexanediol, Methyl Trimethicone, Phaseolus Angularis Seed Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Glyceryl Glucoside, C12-14 Alketh-12, Maltodextrin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethicone Crosspolymer, Ethylhexylglycerin, Betaine, Panthenol, Allantoin, Dipotassium Glycyrrhizate, Polyquaternium-51, Xanthan Gum, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Dioscorea Japonica Root Extract, Glucose, Sodium Citrate, Beta-Glucan, Hydrolyzed Corn Starch, Citric Acid, Sucrose, Magnesium Ascorbyl Phosphate, Caprylyl Glycol, Helianthus Annuus Seed Oil, Tocopherol, Cyanocobalamin, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Acetyl Hexapeptide-8, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Histidine, Cysteine, Methionine, Phosphoric Acid, Ascorbic Acid, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Aspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.
Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.
One study found histidine and carnosine to be a dynamic duo for your skin:
Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.
Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.
Isoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.
Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.
This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.
Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.
Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.
Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Valine is one of the essential amino acids (meaning your body can't make it on its own and has to get it from food).
In skincare, it's usually synthetically-made or pulled from plant proteins like soy.
It's one of the small building blocks that make up your skin's natural moisturizing factor (NMF), or the built-in system that helps skin hold onto water. So its main job in a formula is to give the skin gentle hydration and help it feel more comfortable.
Typical amounts are very tiny: roughly 0.00004%-0.5% in leave on products and up to 1% in rinse-off ones.
The Cosmetic Ingredient Review panel has looked at this ingredient and found no evidence of it being a skin irritant or allergen at cosmetic levels.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.