Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Mary & May Vegan Cica Tea Tree AHA PHA Toner Versus Beauty of Joseon Ginseng Essence Water

Mary & May Vegan Cica Tea Tree AHA PHA Toner Versus Beauty of Joseon Ginseng Essence Water This calming toner is formulated around Melaleuca Alternifolia Leaf Water and Niacinamide to calm redness and refine skin texture. This calming essence is formulated aro

Mary & May Vegan Cica Tea Tree AHA PHA Toner Versus Beauty of Joseon Ginseng Essence Water

This calming toner is formulated around Melaleuca Alternifolia Leaf Water and Niacinamide to calm redness and refine skin texture.

This calming essence is formulated around Panax Ginseng Root Water and Niacinamide to calm redness and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Melaleuca Alternifolia Leaf Water

Glycerin

Dipropylene Glycol

Butylene Glycol

Niacinamide

1,2-Hexanediol

Propanediol

Caprylyl Glycol

C12-14 Pareth-12

Ethylhexylglycerin

Adenosine

Citric Acid

Gluconolactone

Allantoin

Xanthan Gum

Xylitylglucoside

Centella Asiatica Leaf Extract

Anhydroxylitol

Mentha Arvensis Leaf Oil

Xylitol

Glucose

Pinus Densiflora Leaf Extract

Citrus Junos Fruit Extract

Artemisia Annua Extract

Water, Melaleuca Alternifolia Leaf Water, Glycerin, Dipropylene Glycol, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Propanediol, Caprylyl Glycol, C12-14 Pareth-12, Ethylhexylglycerin, Adenosine, Citric Acid, Gluconolactone, Allantoin, Xanthan Gum, Xylitylglucoside, Centella Asiatica Leaf Extract, Anhydroxylitol, Mentha Arvensis Leaf Oil, Xylitol, Glucose, Pinus Densiflora Leaf Extract, Citrus Junos Fruit Extract, Artemisia Annua Extract

Panax Ginseng Root Water

Hydroxyacetophenone

Glyceryl Glucoside

Panthenol

Dipotassium Glycyrrhizate

Panax Ginseng Callus Culture Extract

Theobroma Cacao Extract

Dextrin

Panax Ginseng Root Extract

Panax Ginseng Berry Extract

Lactobacillus/Panax Ginseng Root Extract Ferment Filtrate

Sodium Hyaluronate

Disodium EDTA

Panax Ginseng Root Water, Butylene Glycol, Glycerin, Propanediol, Niacinamide, 1,2-Hexanediol, Water, Hydroxyacetophenone, Glyceryl Glucoside, Xanthan Gum, Panthenol, Dipotassium Glycyrrhizate, Allantoin, Adenosine, Panax Ginseng Callus Culture Extract, Theobroma Cacao Extract, Dextrin, Glucose, Panax Ginseng Root Extract, Panax Ginseng Berry Extract, Lactobacillus/Panax Ginseng Root Extract Ferment Filtrate, Sodium Hyaluronate, Ethylhexylglycerin, Disodium EDTA

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.

Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.

It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.

Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.

Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.

In skincare, glucose is typically derived from corn or other starch sources.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Glycine Soja Oil
  2. 02Cetyl Ethylhexanoate
  3. 03Sorbeth-30 Tetraoleate
  4. 04Isododecane
  5. 05Olea Europaea Fruit Oil
  6. 06Camellia Japonica Seed Oil
  7. 07Hydrogenated Coconut Oil
  8. 08Octyldodecanol
  9. 09Polybutene
  10. 10Caprylic/Capric Triglyceride
  11. 11Water
  12. 12Tocopherol
  13. 13Salvia Officinalis Oil
  14. 14Panax Ginseng Seed Oil
  15. 15Artemisia Vulgaris Oil
  16. 16Ocimum Basilicum Oil
  17. 17Corylus Avellana Seed Oil
  18. 18Nigella Sativa Seed Oil
  19. 19Butylene Glycol
  20. 20Panax Ginseng Berry Extract
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side