Peptide Skincare & BeautySkin science and ingredient guides

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MCoBeauty. Peptide Lip Treatment Versus Olehenriksen Pout Preserve Peptide Lip Treatment

MCoBeauty. Peptide Lip Treatment Versus Olehenriksen Pout Preserve Peptide Lip Treatment This anti-aging lip moisturizer is formulated around Palmitoyl Tripeptide-5 and Butyrospermum Parkii Butter to soften the look of wrinkles and hydrate lips. This anti-agin

MCoBeauty. Peptide Lip Treatment Versus Olehenriksen Pout Preserve Peptide Lip Treatment

This anti-aging lip moisturizer is formulated around Palmitoyl Tripeptide-5 and Butyrospermum Parkii Butter to soften the look of wrinkles and hydrate lips.

This anti-aging lip moisturizer is formulated around Bis-Diglyceryl Polyacyladipate-2 and Palmitoyl Hexapeptide-12 to soften the look of wrinkles and hydrate lips.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Bis-Diglyceryl Polyacyladipate-2

Diisostearyl Malate

Polyisobutene

Hydrogenated Polyisobutene

Microcrystalline Wax

Butyrospermum Parkii Butter

Octyldodecanol

Disteardimonium Hectorite

Synthetic Wax

Phenoxyethanol

Vanillin

Ethylhexyl Palmitate

Zinc Carbonate

Tocopheryl Acetate

Parfum

Tribehenin

Palmitoyl Tripeptide-5

Sorbitan Isostearate

Water

Ricinus Communis Seed Oil

Lactic Acid

Sodium Hyaluronate

Glycerin

Hydrogenated Castor Oil

1,2-Hexanediol

Hydroxypropyl Cyclodextrin

Ethylhexylglycerin

Bis-Diglyceryl Polyacyladipate-2, Diisostearyl Malate, Polyisobutene, Hydrogenated Polyisobutene, Microcrystalline Wax, Butyrospermum Parkii Butter, Octyldodecanol, Disteardimonium Hectorite, Synthetic Wax, Phenoxyethanol, Vanillin, Ethylhexyl Palmitate, Zinc Carbonate, Tocopheryl Acetate, Parfum, Tribehenin, Palmitoyl Tripeptide-5, Sorbitan Isostearate, Water, Ricinus Communis Seed Oil, Lactic Acid, Sodium Hyaluronate, Glycerin, Hydrogenated Castor Oil, 1,2-Hexanediol, Hydroxypropyl Cyclodextrin, Ethylhexylglycerin

Polybutene

Hydrogenated Polydecene

Hydrogenated Styrene/Isoprene Copolymer

Cera Microcristallina

Silica

Rubus Chamaemorus Seed Oil

Garcinia Indica Seed Butter

Euterpe Oleracea Sterols

Palmitoyl Hexapeptide-12

Palmitoyl Tripeptide-1

Tocopherol

Irvingia Gabonensis Kernel Butter

Citrus Aurantium Dulcis Fruit Extract

Linoleic Acid

Linolenic Acid

Oleic Acid

Helianthus Annuus Seed Oil

Caprylic/Capric Triglyceride

Copernicia Cerifera Wax

Hydrogenated Coco-Glycerides

Pentaerythrityl Tetraisostearate

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Dicalcium Phosphate

Propylene Carbonate

Stearalkonium Hectorite

Citral

Limonene

Linalool

Iron Oxides

CI 77891

Polybutene, Hydrogenated Polydecene, Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Styrene/Isoprene Copolymer, Cera Microcristallina, Silica, Rubus Chamaemorus Seed Oil, Garcinia Indica Seed Butter, Euterpe Oleracea Sterols, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Tocopheryl Acetate, Tocopherol, Irvingia Gabonensis Kernel Butter, Citrus Aurantium Dulcis Fruit Extract, Linoleic Acid, Linolenic Acid, Oleic Acid, Lactic Acid, Helianthus Annuus Seed Oil, Caprylic/Capric Triglyceride, Copernicia Cerifera Wax, Hydrogenated Coco-Glycerides, Sorbitan Isostearate, Pentaerythrityl Tetraisostearate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Octyldodecanol, Ethylhexyl Palmitate, Dicalcium Phosphate, Tribehenin, Propylene Carbonate, Stearalkonium Hectorite, Parfum, Citral, Limonene, Linalool, Iron Oxides, CI 77891

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bis-Diglyceryl Polyacyladipate-2 is a synthetic emollient that works as a lanolin substitute.

This ingredient is a great vegan option for those avoiding animal-derived ingredients.

It mostly stays on the surface of skin where it helps hydrate due to its large molecular size and low water solubility.

Due to it being derived from fatty acids, this ingredient may not be Malassezia or fungal acne safe.

Ethylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid.

In cosmetics, it plays many roles:

One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day.

For most people, this is a well-tolerated and lightweight ingredient.

This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize.

Lactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.

Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.

Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.

Like glycolic acid, it can:

Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.

Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.

To get results, choose products with a pH between 3-4.

Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.

Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.

When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.

Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.

Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.

Read more about some other popular AHA's here:

Octyldodecanol is a fatty alcohol sourced from plant oils like coconut or palm (or made synthetically).

It is:

You'll likely see this in many BHA products because this is the go-to solvent for salicylic acid.

This ingredient is typically used at levels between 2-20%.

Regarding fungal acne: In 2019, this ingredient was tested against multiple Malassezia species (the yeast that causes fungal acne) and showed no growth.

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Sorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol.

As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth.

In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%.

Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Tribehenin is the triglyceride of glycerin and behenic acid. It is an emollient that helps soften and condition skin.

Safety-wise, this is a well-vetted ingredient. Repeated-insult patch tests of 0.38% tribehenin did not trigger sensitization.

This ingredient may not be fungal acne safe because behenic acid falls into the chain-length range that Malassezia yeasts can feed on.

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The reference edit

Ingredients, questions
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Product index

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Product

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Comparison edit

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