Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

MediCube Age-R Glutathione Glow Toner Versus The Ordinary Multi Peptides + Copper Peptide 1%

MediCube Age-R Glutathione Glow Toner Versus The Ordinary Multi Peptides + Copper Peptide 1% This brightening toner is formulated around Niacinamide and Glutathione to brighten dull-looking skin and fade the look of dark spots. This anti-aging serum is formula

MediCube Age-R Glutathione Glow Toner Versus The Ordinary Multi Peptides + Copper Peptide 1%

This brightening toner is formulated around Niacinamide and Glutathione to brighten dull-looking skin and fade the look of dark spots.

This anti-aging serum is formulated around Lactococcus Ferment Lysate and Copper Tripeptide-1 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Triethylhexanoin

Hydrogenated Poly(C6-14 Olefin)

Butylene Glycol

1,2-Hexanediol

Methylpropanediol

Niacinamide

Phenyl Trimethicone

Diethoxyethyl Succinate

Polyglyceryl-10 Myristate

Parfum

Hippophae Rhamnoides Oil

Ethylhexylglycerin

Allantoin

Hydrogenated Lecithin

Hibiscus Esculentus Fruit Extract

Corchorus Olitorius Leaf Extract

Carum Petroselinum Extract

Glutathione

Sodium Gluconate

Adenosine

Cellulose Gum

Hexyl Cinnamal

Gluconolactone

Melia Azadirachta Leaf Extract

Linalool

Melia Azadirachta Flower Extract

Lavandula Angustifolia Flower Water

Hyacinthus Orientalis Extract

Centaurea Cyanus Flower Extract

Chamomilla Recutita Flower/Leaf Extract

Curcuma Longa Root Extract

Borago Officinalis Extract

Salvia Sclarea Extract

Limonene

Alpha-Arbutin

Ocimum Sanctum Leaf Extract

Corallina Officinalis Extract

Thioctic Acid

Biotin

Biotinoyl Tripeptide-1

Acetyl Hexapeptide-8

Tripeptide-1

Tripeptide-3

Myristoyl Pentapeptide-17

Hexapeptide-9

Water, Triethylhexanoin, Hydrogenated Poly(C6-14 Olefin), Butylene Glycol, 1,2-Hexanediol, Methylpropanediol, Niacinamide, Phenyl Trimethicone, Diethoxyethyl Succinate, Polyglyceryl-10 Myristate, Parfum, Hippophae Rhamnoides Oil, Ethylhexylglycerin, Allantoin, Hydrogenated Lecithin, Hibiscus Esculentus Fruit Extract, Corchorus Olitorius Leaf Extract, Carum Petroselinum Extract, Glutathione, Sodium Gluconate, Adenosine, Cellulose Gum, Hexyl Cinnamal, Gluconolactone, Melia Azadirachta Leaf Extract, Linalool, Melia Azadirachta Flower Extract, Lavandula Angustifolia Flower Water, Hyacinthus Orientalis Extract, Centaurea Cyanus Flower Extract, Chamomilla Recutita Flower/Leaf Extract, Curcuma Longa Root Extract, Borago Officinalis Extract, Salvia Sclarea Extract, Limonene, Alpha-Arbutin, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Thioctic Acid, Biotin, Biotinoyl Tripeptide-1, Acetyl Hexapeptide-8, Tripeptide-1, Tripeptide-3, Myristoyl Pentapeptide-17, Hexapeptide-9

Glycerin

Lactococcus Ferment Lysate

Copper Tripeptide-1

Pentapeptide-18

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-38

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Acetylarginyltryptophyl Diphenylglycine

Sodium Hyaluronate Crosspolymer

Sodium Hyaluronate

Glycine

Alanine

Serine

Valine

Isoleucine

Proline

Threonine

Histidine

Phenylalanine

Arginine

Aspartic Acid

Trehalose

Fructose

Glucose

Maltose

Urea

Sodium PCA

PCA

Sodium Lactate

Citric Acid

Hydroxypropyl Cyclodextrin

Sodium Chloride

Sodium Hydroxide

Pentylene Glycol

Acacia Senegal Gum

Xanthan Gum

Carbomer

Polysorbate 20

Dimethyl Isosorbide

Sodium Benzoate

Caprylyl Glycol

Phenoxyethanol

Chlorphenesin

Water, Glycerin, Lactococcus Ferment Lysate, Copper Tripeptide-1, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Hydrolyzed Soy Protein
  3. 03Magnesium Chloride
  4. 04Glycerin
  5. 05Hydroxyethylcellulose
  6. 06Polysorbate 20
  7. 07Allantoin
  8. 08Glycine
  9. 09Phenoxyethanol
  10. 10Sodium Salicylate
  11. 11Aloe Barbadensis Leaf Juice
  12. 12Parfum
  13. 13Tocophersolan
  14. 14Water, Hydrolyzed Soy Protein, Magnesium Chloride, Glycerin, Hydroxyethylcellulose, Polysorbate 20, Allantoin, Glycine, Phenoxyethanol, Sodium Salicylate, Aloe Barbadensis Leaf Juice, Parfum, Tocophersolan
  15. 15Lactococcus Ferment Lysate
  16. 16Copper Tripeptide-1
  17. 17Acetyl Hexapeptide-8
  18. 18Pentapeptide-18
  19. 19Palmitoyl Tripeptide-1
  20. 20Palmitoyl Tetrapeptide-7
Source · skinsort.com
02

Product index

Related product references

Product

Nano Recipe Copper Peptide-1

Nano Recipe Copper Peptide-1 Ingredients in Nano Recipe Copper Peptide-1 explained: benefits, concerns, and detailed analysis of 4 ingredients including Copper Tripeptide-1, Water, and Prop…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side