Skin science article
MediCube PDRN Pink Peptide Eye Cream Versus The Ordinary Multi-Peptide Eye Serum
MediCube PDRN Pink Peptide Eye Cream Versus The Ordinary Multi-Peptide Eye Serum This anti-aging eye moisturizer is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles. This anti-aging eye moisturizer is formulated around Niacinamide an
MediCube PDRN Pink Peptide Eye Cream Versus The Ordinary Multi-Peptide Eye Serum
This anti-aging eye moisturizer is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles.
This anti-aging eye moisturizer is formulated around Niacinamide and Palmitoyl Tripeptide-38 to soften the look of wrinkles and fade the look of dark spots.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dipropylene Glycol
Niacinamide
Caprylic/Capric Triglyceride
Pentaerythrityl Tetraethylhexanoate
Cetearyl Alcohol
Glycereth-26
Butylene Glycol Dicaprylate/Dicaprate
Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate
Cetearyl Olivate
Sorbitan Olivate
Propylene Glycol Dibenzoate
Pullulan
1,2-Hexanediol
Glyceryl Stearate
Vinyldimethicone
Hydroxyacetophenone
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Hydrogenated Lecithin
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Sodium DNA
Polyisobutene
Butylene Glycol
Ethylhexylglycerin
Propanediol
Melia Azadirachta Leaf Extract
Adenosine
Melia Azadirachta Flower Extract
Curcuma Longa Root Extract
Sorbitan Isostearate
Sorbitan Oleate
Caprylyl/Capryl Glucoside
Fragaria Chiloensis Fruit Extract
Hedera Helix Leaf/Stem Extract
Cyanocobalamin
Citrus Nobilis Peel Extract
Retinol
Ocimum Sanctum Leaf Extract
Lespedeza Capitata Leaf/Stem Extract
Corallina Officinalis Extract
Sodium Hyaluronate
Caffeine
Coffea Arabica Seed Extract
Hydrolyzed Extensin
Hydrolyzed Hyaluronic Acid
Copper Tripeptide-1
Sodium Acetylated Hyaluronate
Acetyl Hexapeptide-8
Palmitoyl Pentapeptide-4
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Water, Glycerin, Dipropylene Glycol, Niacinamide, Caprylic/Capric Triglyceride, Pentaerythrityl Tetraethylhexanoate, Cetearyl Alcohol, Glycereth-26, Butylene Glycol Dicaprylate/Dicaprate, Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate, Cetearyl Olivate, Sorbitan Olivate, Propylene Glycol Dibenzoate, Pullulan, 1,2-Hexanediol, Glyceryl Stearate, Vinyldimethicone, Hydroxyacetophenone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Lecithin, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium DNA, Polyisobutene, Butylene Glycol, Ethylhexylglycerin, Propanediol, Melia Azadirachta Leaf Extract, Adenosine, Melia Azadirachta Flower Extract, Curcuma Longa Root Extract, Sorbitan Isostearate, Sorbitan Oleate, Caprylyl/Capryl Glucoside, Fragaria Chiloensis Fruit Extract, Hedera Helix Leaf/Stem Extract, Cyanocobalamin, Citrus Nobilis Peel Extract, Retinol, Ocimum Sanctum Leaf Extract, Lespedeza Capitata Leaf/Stem Extract, Corallina Officinalis Extract, Sodium Hyaluronate, Caffeine, Coffea Arabica Seed Extract, Hydrolyzed Extensin, Hydrolyzed Hyaluronic Acid, Copper Tripeptide-1, Sodium Acetylated Hyaluronate, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1
Acetyl Glucosamine
Palmitoyl Tripeptide-38
Acetyl Tetrapeptide-5
Myristoyl Nonapeptide-3
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Epigallocatechin Gallatyl Glucoside
Gallyl Glucoside
Fraxinus Excelsior Bark Extract
Silanetriol
Arginine
Pentylene Glycol
Hydroxymethoxyphenyl Decanone
Propyl Gallate
Maltodextrin
Hydroxypropyl Cyclodextrin
Hydroxyethylcellulose
Xanthan Gum
Citric Acid
Glycolic Acid
Sodium Citrate
Polysorbate 20
Trisodium Ethylenediamine Disuccinate
Dehydroacetic Acid
Benzyl Alcohol
Phenoxyethanol
Chlorphenesin
Water, Glycerin, Butylene Glycol, Propanediol, Dipropylene Glycol, Acetyl Glucosamine, Niacinamide, Palmitoyl Tripeptide-38, Acetyl Tetrapeptide-5, Myristoyl Nonapeptide-3, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Caffeine, Epigallocatechin Gallatyl Glucoside, Gallyl Glucoside, Fraxinus Excelsior Bark Extract, Silanetriol, Arginine, Pentylene Glycol, Hydroxymethoxyphenyl Decanone, Propyl Gallate, Maltodextrin, Hydroxypropyl Cyclodextrin, Hydroxyethylcellulose, Xanthan Gum, Citric Acid, Glycolic Acid, Sodium Citrate, Polysorbate 20, Trisodium Ethylenediamine Disuccinate, Dehydroacetic Acid, Ethylhexylglycerin, Benzyl Alcohol, Phenoxyethanol, Chlorphenesin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.
As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.
Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.
You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.
Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.
Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.
Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.
This ingredient helps:
Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!