Skin science article
MediCube PDRN Pink Peptide Serum Versus The Ordinary Argireline Solution 10%
MediCube PDRN Pink Peptide Serum Versus The Ordinary Argireline Solution 10% This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Acetyl Hexapep
MediCube PDRN Pink Peptide Serum Versus The Ordinary Argireline Solution 10%
This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Acetyl Hexapeptide-8 to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dipropylene Glycol
Isopropyl Myristate
Glycereth-26
Niacinamide
1,2-Hexanediol
Sodium DNA
Butylene Glycol
Polyglycerin-3
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Polyisobutene
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Milt Extract
Tromethamine
Glyceryl Acrylate/Acrylic Acid Copolymer
Pvm/Ma Copolymer
Ethylhexylglycerin
Caprylyl Glycol
Parfum
Melia Azadirachta Leaf Extract
Adenosine
Caprylyl/Capryl Glucoside
Sorbitan Oleate
Melia Azadirachta Flower Extract
Sodium Hyaluronate
Disodium EDTA
Curcuma Longa Root Extract
Cyanocobalamin
Hydrolyzed Collagen
Ubiquinone
Ocimum Sanctum Leaf Extract
Corallina Officinalis Extract
Palmitoyl Pentapeptide-4
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Copper Tripeptide-1
Acetyl Hexapeptide-8
Salmon Egg Extract
Atelocollagen
Water, Glycerin, Dipropylene Glycol, Isopropyl Myristate, Glycereth-26, Niacinamide, 1,2-Hexanediol, Sodium DNA, Butylene Glycol, Polyglycerin-3, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Milt Extract, Tromethamine, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, Ethylhexylglycerin, Caprylyl Glycol, Parfum, Melia Azadirachta Leaf Extract, Adenosine, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Melia Azadirachta Flower Extract, Sodium Hyaluronate, Disodium EDTA, Curcuma Longa Root Extract, Cyanocobalamin, Hydrolyzed Collagen, Ubiquinone, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Acetyl Hexapeptide-8, Salmon Egg Extract, Atelocollagen
Propanediol
Trisodium Ethylenediamine Disuccinate
Gellan Gum
Sodium Chloride
Isoceteth-20
Dimethyl Isosorbide
Potassium Sorbate
Phenoxyethanol
Chlorphenesin
Water, Propanediol, Acetyl Hexapeptide-8, Trisodium Ethylenediamine Disuccinate, Gellan Gum, Sodium Chloride, Isoceteth-20, Dimethyl Isosorbide, Potassium Sorbate, Phenoxyethanol, Chlorphenesin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!