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MediCube PDRN Pink Peptide Serum Versus ZO Skin Health Wrinkle + Texture Repair

MediCube PDRN Pink Peptide Serum Versus ZO Skin Health Wrinkle + Texture Repair This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and refine skin texture. This anti-aging treatment is formulated around Retinol

MediCube PDRN Pink Peptide Serum Versus ZO Skin Health Wrinkle + Texture Repair

This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and refine skin texture.

This anti-aging treatment is formulated around Retinol to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dipropylene Glycol

Isopropyl Myristate

Glycereth-26

Niacinamide

1,2-Hexanediol

Sodium DNA

Butylene Glycol

Polyglycerin-3

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Polyisobutene

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Milt Extract

Tromethamine

Glyceryl Acrylate/Acrylic Acid Copolymer

Pvm/Ma Copolymer

Ethylhexylglycerin

Caprylyl Glycol

Parfum

Melia Azadirachta Leaf Extract

Adenosine

Caprylyl/Capryl Glucoside

Sorbitan Oleate

Melia Azadirachta Flower Extract

Sodium Hyaluronate

Disodium EDTA

Curcuma Longa Root Extract

Cyanocobalamin

Hydrolyzed Collagen

Ubiquinone

Ocimum Sanctum Leaf Extract

Corallina Officinalis Extract

Palmitoyl Pentapeptide-4

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Copper Tripeptide-1

Acetyl Hexapeptide-8

Salmon Egg Extract

Atelocollagen

Water, Glycerin, Dipropylene Glycol, Isopropyl Myristate, Glycereth-26, Niacinamide, 1,2-Hexanediol, Sodium DNA, Butylene Glycol, Polyglycerin-3, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Milt Extract, Tromethamine, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, Ethylhexylglycerin, Caprylyl Glycol, Parfum, Melia Azadirachta Leaf Extract, Adenosine, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Melia Azadirachta Flower Extract, Sodium Hyaluronate, Disodium EDTA, Curcuma Longa Root Extract, Cyanocobalamin, Hydrolyzed Collagen, Ubiquinone, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Acetyl Hexapeptide-8, Salmon Egg Extract, Atelocollagen

Cetearyl Isononanoate

Cyclopentasiloxane

Cetearyl Alcohol

Cyclohexasiloxane

Steareth-20

Pentylene Glycol

Cetyl Alcohol

Propylheptyl Caprylate

Prunus Armeniaca Kernel Oil

Lavandula Angustifolia Oil

Pelargonium Graveolens Flower Oil

Melilotus Officinalis Extract

Buddleja Davidii Meristem Cell Culture

Retinol 0.5%

Cetearyl Glucoside

Polysorbate 20

Acrylamide/Ammonium Acrylate Copolymer

Lecithin

Bisabolol

Carbomer

Silica

Hydrolyzed Sericin

Phospholipids

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Sodium Hydroxide

BHT

Sodium Metabisulfite

Sodium Sulfite

Ascorbyl Palmitate

Tocopheryl Acetate

Beta-Glucan

Sorbitan Isostearate

Hexylene Glycol

Xanthan Gum

Ethyl Nicotinate

Caprooyl Tetrapeptide-3

Dextran

Potassium Sorbate

Phenoxyethanol

CI 60730

Linalool

Citronellol

Geraniol

Citral

Limonene

Water, Cetearyl Isononanoate, Cyclopentasiloxane, Glycerin, Cetearyl Alcohol, Cyclohexasiloxane, Steareth-20, Pentylene Glycol, Cetyl Alcohol, Propylheptyl Caprylate, Prunus Armeniaca Kernel Oil, Lavandula Angustifolia Oil, Pelargonium Graveolens Flower Oil, Melilotus Officinalis Extract, Buddleja Davidii Meristem Cell Culture, Retinol 0.5%, Cetearyl Glucoside, Polysorbate 20, Acrylamide/Ammonium Acrylate Copolymer, 1,2-Hexanediol, Lecithin, Bisabolol, Carbomer, Silica, Polyisobutene, Butylene Glycol, Hydrolyzed Sericin, Phospholipids, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Hydroxide, Disodium EDTA, BHT, Sodium Metabisulfite, Sodium Sulfite, Ascorbyl Palmitate, Tocopheryl Acetate, Beta-Glucan, Sorbitan Isostearate, Hexylene Glycol, Xanthan Gum, Ethylhexylglycerin, Ethyl Nicotinate, Caprooyl Tetrapeptide-3, Dextran, Caprylyl Glycol, Potassium Sorbate, Phenoxyethanol, CI 60730, Linalool, Citronellol, Geraniol, Citral, Limonene

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Polyisobutene is a synthetic polymer made from isobutene.

It is a film-forming agent and helps bind ingredients together.

Polyisobutene is not absorbed by the skin.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
  10. 10The way it works is fairly well mapped out:
  11. 11Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down o…
  12. 12The clinical backing is pretty solid too.
  13. 13A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at…
  14. 14A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
  15. 15On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
  16. 16This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
  17. 17Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
  18. 18Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  19. 19Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  20. 20Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Source · skinsort.com
02

Product index

Related product references

Product

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MediCube PDRN Pink Peptide Serum Ingredients in MediCube PDRN Pink Peptide Serum Salmon DNA explained: benefits, concerns, and detailed analysis of 40 ingredients including Water, Glycerin,…

Source: skinsort.comView reference →
03

Comparison edit

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