Skin science article
MediCube PDRN Pink Peptide Serum Versus ZO Skin Health Wrinkle + Texture Repair
MediCube PDRN Pink Peptide Serum Versus ZO Skin Health Wrinkle + Texture Repair This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and refine skin texture. This anti-aging treatment is formulated around Retinol
MediCube PDRN Pink Peptide Serum Versus ZO Skin Health Wrinkle + Texture Repair
This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and refine skin texture.
This anti-aging treatment is formulated around Retinol to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dipropylene Glycol
Isopropyl Myristate
Glycereth-26
Niacinamide
1,2-Hexanediol
Sodium DNA
Butylene Glycol
Polyglycerin-3
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Polyisobutene
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Milt Extract
Tromethamine
Glyceryl Acrylate/Acrylic Acid Copolymer
Pvm/Ma Copolymer
Ethylhexylglycerin
Caprylyl Glycol
Parfum
Melia Azadirachta Leaf Extract
Adenosine
Caprylyl/Capryl Glucoside
Sorbitan Oleate
Melia Azadirachta Flower Extract
Sodium Hyaluronate
Disodium EDTA
Curcuma Longa Root Extract
Cyanocobalamin
Hydrolyzed Collagen
Ubiquinone
Ocimum Sanctum Leaf Extract
Corallina Officinalis Extract
Palmitoyl Pentapeptide-4
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Copper Tripeptide-1
Acetyl Hexapeptide-8
Salmon Egg Extract
Atelocollagen
Water, Glycerin, Dipropylene Glycol, Isopropyl Myristate, Glycereth-26, Niacinamide, 1,2-Hexanediol, Sodium DNA, Butylene Glycol, Polyglycerin-3, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Milt Extract, Tromethamine, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, Ethylhexylglycerin, Caprylyl Glycol, Parfum, Melia Azadirachta Leaf Extract, Adenosine, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Melia Azadirachta Flower Extract, Sodium Hyaluronate, Disodium EDTA, Curcuma Longa Root Extract, Cyanocobalamin, Hydrolyzed Collagen, Ubiquinone, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Acetyl Hexapeptide-8, Salmon Egg Extract, Atelocollagen
Cetearyl Isononanoate
Cyclopentasiloxane
Cetearyl Alcohol
Cyclohexasiloxane
Steareth-20
Pentylene Glycol
Cetyl Alcohol
Propylheptyl Caprylate
Prunus Armeniaca Kernel Oil
Lavandula Angustifolia Oil
Pelargonium Graveolens Flower Oil
Melilotus Officinalis Extract
Buddleja Davidii Meristem Cell Culture
Retinol 0.5%
Cetearyl Glucoside
Polysorbate 20
Acrylamide/Ammonium Acrylate Copolymer
Lecithin
Bisabolol
Carbomer
Silica
Hydrolyzed Sericin
Phospholipids
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Sodium Hydroxide
BHT
Sodium Metabisulfite
Sodium Sulfite
Ascorbyl Palmitate
Tocopheryl Acetate
Beta-Glucan
Sorbitan Isostearate
Hexylene Glycol
Xanthan Gum
Ethyl Nicotinate
Caprooyl Tetrapeptide-3
Dextran
Potassium Sorbate
Phenoxyethanol
CI 60730
Linalool
Citronellol
Geraniol
Citral
Limonene
Water, Cetearyl Isononanoate, Cyclopentasiloxane, Glycerin, Cetearyl Alcohol, Cyclohexasiloxane, Steareth-20, Pentylene Glycol, Cetyl Alcohol, Propylheptyl Caprylate, Prunus Armeniaca Kernel Oil, Lavandula Angustifolia Oil, Pelargonium Graveolens Flower Oil, Melilotus Officinalis Extract, Buddleja Davidii Meristem Cell Culture, Retinol 0.5%, Cetearyl Glucoside, Polysorbate 20, Acrylamide/Ammonium Acrylate Copolymer, 1,2-Hexanediol, Lecithin, Bisabolol, Carbomer, Silica, Polyisobutene, Butylene Glycol, Hydrolyzed Sericin, Phospholipids, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Hydroxide, Disodium EDTA, BHT, Sodium Metabisulfite, Sodium Sulfite, Ascorbyl Palmitate, Tocopheryl Acetate, Beta-Glucan, Sorbitan Isostearate, Hexylene Glycol, Xanthan Gum, Ethylhexylglycerin, Ethyl Nicotinate, Caprooyl Tetrapeptide-3, Dextran, Caprylyl Glycol, Potassium Sorbate, Phenoxyethanol, CI 60730, Linalool, Citronellol, Geraniol, Citral, Limonene
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Polyisobutene is a synthetic polymer made from isobutene.
It is a film-forming agent and helps bind ingredients together.
Polyisobutene is not absorbed by the skin.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!