MediCube Triple Collagen Serum Versus Haruharu Wonder Black Rice Hyaluronic Anti-Wrinkle Serum

MediCube Triple Collagen Serum Versus Haruharu Wonder Black Rice Hyaluronic Anti-Wrinkle Serum

This anti-aging serum is formulated around Niacinamide and Adenosine to soften the look of wrinkles.

This anti-aging serum is formulated around Oryza Sativa Extract and Hyaluronic Acid to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Sea Water

Glycerin

Butylene Glycol

Cetyl Ethylhexanoate

1,2-Hexanediol

Alcohol Denat.

Niacinamide

Glycereth-26

Adenosine

Hydrolyzed Collagen

Hyaluronic Acid

Hydrolyzed Hyaluronic Acid

Sodium Hyaluronate

Soluble Collagen

Collagen Extract

Atelocollagen

Propanediol

Cyclopentasiloxane

Trehalose

Carbomer

Cetearyl Olivate

Tromethamine

Cyclohexasiloxane

Sorbitan Olivate

Ethylhexylglycerin

Disodium EDTA

Dimethicone

Parfum

Sea Water, Glycerin, Butylene Glycol, Cetyl Ethylhexanoate, 1,2-Hexanediol, Alcohol Denat., Niacinamide, Glycereth-26, Adenosine, Hydrolyzed Collagen, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Soluble Collagen, Collagen Extract, Atelocollagen, Propanediol, Cyclopentasiloxane, Trehalose, Carbomer, Cetearyl Olivate, Tromethamine, Cyclohexasiloxane, Sorbitan Olivate, Ethylhexylglycerin, Disodium EDTA, Dimethicone, Parfum

Water

Lecithin

Caprylic/Capric Triglyceride

Camellia Japonica Seed Oil

Hydrogenated Lecithin

Helianthus Annuus Seed Oil

Oryza Sativa Extract

Phyllostachys Pubescens Shoot Bark Extract

Aspergillus Ferment

Panax Ginseng Root Extract

Cyclodextrin

Sclerotium Gum

C12-16 Alcohols

Palmitic Acid

Alteromonas Ferment Extract

Usnea Barbata Extract

Zanthoxylum Piperitum Fruit Extract

Pulsatilla Koreana Extract

Beta-Glucan

Glycine Soja Sterols

Behenyl Alcohol

Simmondsia Chinensis Seed Oil

Glyceryl Stearate

Sodium Phytate

Tocopherol

Phenethyl Alcohol

Alcohol

Lavandula Angustifolia Oil

Linalool

Limonene

Water, Glycerin, Lecithin, Caprylic/Capric Triglyceride, Camellia Japonica Seed Oil, Hydrogenated Lecithin, Helianthus Annuus Seed Oil, Oryza Sativa Extract, Phyllostachys Pubescens Shoot Bark Extract, Aspergillus Ferment, Hyaluronic Acid, Panax Ginseng Root Extract, Cyclodextrin, Sclerotium Gum, C12-16 Alcohols, Palmitic Acid, Alteromonas Ferment Extract, Usnea Barbata Extract, Zanthoxylum Piperitum Fruit Extract, Pulsatilla Koreana Extract, Beta-Glucan, 1,2-Hexanediol, Glycine Soja Sterols, Behenyl Alcohol, Simmondsia Chinensis Seed Oil, Glyceryl Stearate, Sodium Phytate, Tocopherol, Adenosine, Phenethyl Alcohol, Butylene Glycol, Alcohol, Lavandula Angustifolia Oil, Linalool, Limonene

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

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