Skin science article
Mediheal Tea Tree Biome Blemish Cica Gel Cleanser Versus Paula's Choice Calm Ultra-Gentle Cleanser
Mediheal Tea Tree Biome Blemish Cica Gel Cleanser Versus Paula's Choice Calm Ultra-Gentle Cleanser This mild gel cleanser is made to cleanse while calming and soothing your skin. What's inside Key Ingredients Benefits Concerns Ingredients Side-by-side Water Co
Mediheal Tea Tree Biome Blemish Cica Gel Cleanser Versus Paula's Choice Calm Ultra-Gentle Cleanser
This mild gel cleanser is made to cleanse while calming and soothing your skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Coco-Betaine
Glycerin
Butylene Glycol
Melaleuca Alternifolia Leaf Water
Aloe Barbadensis Leaf Water
1,2-Hexanediol
Sodium Chloride
Centella Asiatica Extract
Camellia Sinensis Leaf Extract
Glycyrrhiza Glabra Root Extract
Rosmarinus Officinalis Leaf Extract
Potassium Cocoyl Glycinate
Melilotus Officinalis Extract
Tromethamine
Asiaticoside
Madecassic Acid
Asiatic Acid
Gluconolactone
Xylitol
Ethylhexylglycerin
Salix Alba Bark Extract
Anhydroxylitol
Glucose
Melia Azadirachta Flower Extract
Chaenomeles Sinensis Fruit Extract
Citrus Aurantium Dulcis Flower Extract
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Cutibacterium Granulosum Ferment Extract Filtrate
Xylitylglucoside
Polyglyceryl-4 Caprate
Chamomilla Recutita Flower Extract
Melia Azadirachta Leaf Extract
Polygonum Cuspidatum Root Extract
Scutellaria Baicalensis Root Extract
Water, Coco-Betaine, Glycerin, Butylene Glycol, Melaleuca Alternifolia Leaf Water, Aloe Barbadensis Leaf Water, 1,2-Hexanediol, Sodium Chloride, Centella Asiatica Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Rosmarinus Officinalis Leaf Extract, Potassium Cocoyl Glycinate, Melilotus Officinalis Extract, Tromethamine, Asiaticoside, Madecassic Acid, Asiatic Acid, Gluconolactone, Xylitol, Ethylhexylglycerin, Salix Alba Bark Extract, Anhydroxylitol, Glucose, Melia Azadirachta Flower Extract, Chaenomeles Sinensis Fruit Extract, Citrus Aurantium Dulcis Flower Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cutibacterium Granulosum Ferment Extract Filtrate, Xylitylglucoside, Polyglyceryl-4 Caprate, Chamomilla Recutita Flower Extract, Melia Azadirachta Leaf Extract, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract
Sodium Cocoyl Glutamate
Caprylic/Capric Triglyceride
Cocamidopropyl Betaine
Sodium Laurylglucosides Hydroxypropylsulfonate
Cellulose Gum
Coco-Caprylate/Caprate
Hydroxyacetophenone
Inulin
Xanthan Gum
Sodium Phytate
Cellulose
Fructose
Phenoxyethanol
Water, Sodium Cocoyl Glutamate, Glycerin, Caprylic/Capric Triglyceride, Cocamidopropyl Betaine, Sodium Laurylglucosides Hydroxypropylsulfonate, Cellulose Gum, Coco-Caprylate/Caprate, Hydroxyacetophenone, Inulin, Xanthan Gum, Ethylhexylglycerin, Sodium Phytate, Cellulose, Fructose, Glucose, Phenoxyethanol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.
Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.
It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.
Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.
Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.
In skincare, glucose is typically derived from corn or other starch sources.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!