Skin science article
Medik8 Liquid Peptides Advanced MP Versus Dieux Skin Deliverance
Medik8 Liquid Peptides Advanced MP Versus Dieux Skin Deliverance This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This calming serum is formulated around Niaci
Medik8 Liquid Peptides Advanced MP Versus Dieux Skin Deliverance
This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture.
This calming serum is formulated around Niacinamide and Cannabidiol - Synthetically Produced to calm redness and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dimethicone
Dimethyl Isosorbide
Butylene Glycol
Undecane
Arginine
Inulin
Microcrystalline Cellulose
Ceteareth-20
Tridecane
Tocopherol
Hydroxyacetophenone
Sodium Hyaluronate
Palmitoyl Tripeptide-38
Panthenol
Caprylic/Capric Triglyceride
Palmitoyl Tripeptide-5
Polyacrylate Crosspolymer-6
Palmitoyl Tripeptide-1
Pullulan
Tetrapeptide-21
Palmitoyl Tetrapeptide-10
Palmitoyl Tetrapeptide-7
Ammonium Polyacryloyldimethyl Taurate
Glyceryl Linoleate
Acetyl Hexapeptide-8
Pentapeptide-18
Oligopeptide-1
Arginine/Lysine Polypeptide
Sucrose Palmitate
Cetyl Palmitate
Phenoxyethanol
Ethylhexylglycerin
Carbomer
Copper Palmitoyl Heptapeptide-14
Heptapeptide-15 Palmitate
Benzotriazolyl Dodecyl P-Cresol
Polysorbate 80
Sorbitan Stearate
Polysorbate 20
Carnosine
Sodium Metabisulfite
Dunaliella Salina Extract
Helianthus Annuus Seed Oil
Hydroxypropyl Cyclodextrin
Dimethicone/Vinyl Dimethicone Crosspolymer
Sodium Benzoate
Hydrogenated Lecithin
Caprylyl Glycol
Pantolactone
Xanthan Gum
Disodium EDTA
T-Butyl Alcohol
Potassium Sorbate
Citric Acid
Glyceryl Caprylate
Lactic Acid/Glycolic Acid Copolymer
Polyvinyl Alcohol
Phenylpropanol
Water, Glycerin, Dimethicone, Dimethyl Isosorbide, Butylene Glycol, Undecane, Arginine, Inulin, Microcrystalline Cellulose, Ceteareth-20, Tridecane, Tocopherol, Hydroxyacetophenone, Sodium Hyaluronate, Palmitoyl Tripeptide-38, Panthenol, Caprylic/Capric Triglyceride, Palmitoyl Tripeptide-5, Polyacrylate Crosspolymer-6, Palmitoyl Tripeptide-1, Pullulan, Tetrapeptide-21, Palmitoyl Tetrapeptide-10, Palmitoyl Tetrapeptide-7, Ammonium Polyacryloyldimethyl Taurate, Glyceryl Linoleate, Acetyl Hexapeptide-8, Pentapeptide-18, Oligopeptide-1, Arginine/Lysine Polypeptide, Sucrose Palmitate, Cetyl Palmitate, Phenoxyethanol, Ethylhexylglycerin, Carbomer, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Benzotriazolyl Dodecyl P-Cresol, Polysorbate 80, Sorbitan Stearate, Polysorbate 20, Carnosine, Sodium Metabisulfite, Dunaliella Salina Extract, Helianthus Annuus Seed Oil, Hydroxypropyl Cyclodextrin, Dimethicone/Vinyl Dimethicone Crosspolymer, Sodium Benzoate, Hydrogenated Lecithin, Caprylyl Glycol, Pantolactone, Xanthan Gum, Disodium EDTA, T-Butyl Alcohol, Potassium Sorbate, Citric Acid, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol
Niacinamide
Dipropylene Glycol
Propanediol
Cyclodextrin
Methylpropanediol
Sodium Palmitoyl Proline
Pentylene Glycol
Sodium Polyacrylate
Butyrospermum Parkii Butter
Polysilicone-11
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Cannabigerol
Cannabidiol - Synthetically Produced
Sodium Phytate
Camellia Sinensis Leaf Extract
Palmitoyl Hexapeptide-52
Passiflora Incarnata Extract
Decyl Glucoside
Sea Water Extract
N-Prolyl Palmitoyl Tripeptide-56 Acetate
Water, Niacinamide, Glycerin, Dipropylene Glycol, Propanediol, Dimethicone, Cyclodextrin, Methylpropanediol, Sodium Palmitoyl Proline, Pentylene Glycol, Caprylyl Glycol, Phenoxyethanol, Sodium Polyacrylate, Butyrospermum Parkii Butter, Polysilicone-11, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Butylene Glycol, Cannabigerol, Cannabidiol - Synthetically Produced, Sodium Phytate, Camellia Sinensis Leaf Extract, Palmitoyl Hexapeptide-52, Passiflora Incarnata Extract, Decyl Glucoside, Sea Water Extract, N-Prolyl Palmitoyl Tripeptide-56 Acetate
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!