Skin science article
Medik8 Liquid Peptides Versus Niod Survival 0
Medik8 Liquid Peptides Versus Niod Survival 0 This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Superoxide Dismutase and Astaxanthi
Medik8 Liquid Peptides Versus Niod Survival 0
This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Superoxide Dismutase and Astaxanthin to soften the look of wrinkles and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Butylene Glycol
Inulin
Sodium Hyaluronate
Panthenol
Alpha-Glucan Oligosaccharide
Carnosine
Carbomer
Polysorbate 20
Caprylyl Glycol
Phenoxyethanol
Hydroxypropyl Cyclodextrin
Dunaliella Salina Extract
Ethylhexylglycerin
Citric Acid
Palmitoyl Tripeptide-5
Sodium Benzoate
Acetyl Hexapeptide-8
Tetrapeptide-21
Pentapeptide-18
Palmitoyl Tripeptide-1
Pantolactone
Palmitoyl Tripeptide-38
Palmitoyl Tetrapeptide-7
Glyceryl Caprylate
Lactic Acid/Glycolic Acid Copolymer
Polyvinyl Alcohol
Phenylpropanol
Copper Palmitoyl Heptapeptide-14
Heptapeptide-15 Palmitate
Potassium Sorbate
Xanthan Gum
Water, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum
Caprylic/Capric Triglyceride
Solanum Lycopersicum Fruit Extract
Superoxide Dismutase
Dimethylmethoxy Chromanol
Xanthophylls
Astaxanthin
Pinus Pinaster Bark Extract
Polygonum Aviculare Extract
Alteromonas Ferment Extract
Padina Pavonica Thallus Extract
Arginine
Glycine
Alanine
Serine
Valine
Proline
Threonine
Isoleucine
Histidine
Phenylalanine
Aspartic Acid
PCA
Sodium PCA
Sodium Lactate
Piper Cubeba Fruit Extract
Haematococcus Pluvialis Extract
Squalane
Simmondsia Chinensis Seed Oil
Melanin
Sucrose
Lysolecithin
Tapioca Starch
Propanediol
Pentylene Glycol
Polyglyceryl-10 Oleate
Polyglyceryl-10 Stearate
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Trisodium Ethylenediamine Disuccinate
Tromethamine
Triethanolamine
Ethoxydiglycol
Tocopherol
1,2-Hexanediol
Water, Caprylic/Capric Triglyceride, Glycerin, Inulin, Alpha-Glucan Oligosaccharide, Solanum Lycopersicum Fruit Extract, Superoxide Dismutase, Dimethylmethoxy Chromanol, Xanthophylls, Astaxanthin, Pinus Pinaster Bark Extract, Polygonum Aviculare Extract, Alteromonas Ferment Extract, Padina Pavonica Thallus Extract, Arginine, Glycine, Alanine, Serine, Valine, Proline, Threonine, Isoleucine, Histidine, Phenylalanine, Aspartic Acid, PCA, Sodium PCA, Sodium Lactate, Piper Cubeba Fruit Extract, Haematococcus Pluvialis Extract, Squalane, Simmondsia Chinensis Seed Oil, Melanin, Sucrose, Lysolecithin, Tapioca Starch, Propanediol, Pentylene Glycol, Butylene Glycol, Polyglyceryl-10 Oleate, Polyglyceryl-10 Stearate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Trisodium Ethylenediamine Disuccinate, Tromethamine, Triethanolamine, Ethoxydiglycol, Tocopherol, Potassium Sorbate, Sodium Benzoate, 1,2-Hexanediol, Ethylhexylglycerin, Phenoxyethanol, Caprylyl Glycol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Alpha-Glucan Oligosaccharide is a prebiotic. It prevents harmful bacteria from growing on skin by keeping the skin's microbiome in balance.
Another benefit of this ingredient is its antioxidant properties. Antioxidants protect our skin from oxidative damage.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Inulin is a polysaccharide (carbohydrate) with prebiotic and antioxidant properties.
The majority of inulin is extracted from chicory, but can also be obtained from other plants such as garlic, onion, asparagus, and sugarcane.
Studies show inulin may help with controlling your skin's natural microbiota when applied topically.
The antioxidant potential of inulin varies depending on the source.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!