Skin science article
Medik8 Oxy-R Peptides Versus Medik8 Liquid Peptides Advanced MP
Medik8 Oxy-R Peptides Versus Medik8 Liquid Peptides Advanced MP This brightening serum is formulated around Gluconolactone to fade the look of dark spots and brighten dull-looking skin. This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Pal
Medik8 Oxy-R Peptides Versus Medik8 Liquid Peptides Advanced MP
This brightening serum is formulated around Gluconolactone to fade the look of dark spots and brighten dull-looking skin.
This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Artocarpus Lakoocha Wood Extract
Gluconolactone
Acetyl Glycyl Beta-Alanine
Glycerin
Lactic Acid
Sodium Benzoate
Disodium EDTA
Sodium Hyaluronate
Xanthan Gum
Calcium Gluconate
Sodium Metabisulfite
Tetrapeptide-30
Hydroxyresveratrol
Water, Butylene Glycol, Artocarpus Lakoocha Wood Extract, Gluconolactone, Acetyl Glycyl Beta-Alanine, Glycerin, Lactic Acid, Sodium Benzoate, Disodium EDTA, Sodium Hyaluronate, Xanthan Gum, Calcium Gluconate, Sodium Metabisulfite, Tetrapeptide-30, Hydroxyresveratrol
Dimethicone
Dimethyl Isosorbide
Undecane
Arginine
Inulin
Microcrystalline Cellulose
Ceteareth-20
Tridecane
Tocopherol
Hydroxyacetophenone
Palmitoyl Tripeptide-38
Panthenol
Caprylic/Capric Triglyceride
Palmitoyl Tripeptide-5
Polyacrylate Crosspolymer-6
Palmitoyl Tripeptide-1
Pullulan
Tetrapeptide-21
Palmitoyl Tetrapeptide-10
Palmitoyl Tetrapeptide-7
Ammonium Polyacryloyldimethyl Taurate
Glyceryl Linoleate
Acetyl Hexapeptide-8
Pentapeptide-18
Oligopeptide-1
Arginine/Lysine Polypeptide
Sucrose Palmitate
Cetyl Palmitate
Phenoxyethanol
Ethylhexylglycerin
Carbomer
Copper Palmitoyl Heptapeptide-14
Heptapeptide-15 Palmitate
Benzotriazolyl Dodecyl P-Cresol
Polysorbate 80
Sorbitan Stearate
Polysorbate 20
Carnosine
Dunaliella Salina Extract
Helianthus Annuus Seed Oil
Hydroxypropyl Cyclodextrin
Dimethicone/Vinyl Dimethicone Crosspolymer
Hydrogenated Lecithin
Caprylyl Glycol
Pantolactone
T-Butyl Alcohol
Potassium Sorbate
Citric Acid
Glyceryl Caprylate
Lactic Acid/Glycolic Acid Copolymer
Polyvinyl Alcohol
Phenylpropanol
Water, Glycerin, Dimethicone, Dimethyl Isosorbide, Butylene Glycol, Undecane, Arginine, Inulin, Microcrystalline Cellulose, Ceteareth-20, Tridecane, Tocopherol, Hydroxyacetophenone, Sodium Hyaluronate, Palmitoyl Tripeptide-38, Panthenol, Caprylic/Capric Triglyceride, Palmitoyl Tripeptide-5, Polyacrylate Crosspolymer-6, Palmitoyl Tripeptide-1, Pullulan, Tetrapeptide-21, Palmitoyl Tetrapeptide-10, Palmitoyl Tetrapeptide-7, Ammonium Polyacryloyldimethyl Taurate, Glyceryl Linoleate, Acetyl Hexapeptide-8, Pentapeptide-18, Oligopeptide-1, Arginine/Lysine Polypeptide, Sucrose Palmitate, Cetyl Palmitate, Phenoxyethanol, Ethylhexylglycerin, Carbomer, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Benzotriazolyl Dodecyl P-Cresol, Polysorbate 80, Sorbitan Stearate, Polysorbate 20, Carnosine, Sodium Metabisulfite, Dunaliella Salina Extract, Helianthus Annuus Seed Oil, Hydroxypropyl Cyclodextrin, Dimethicone/Vinyl Dimethicone Crosspolymer, Sodium Benzoate, Hydrogenated Lecithin, Caprylyl Glycol, Pantolactone, Xanthan Gum, Disodium EDTA, T-Butyl Alcohol, Potassium Sorbate, Citric Acid, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sodium metabisulfite is also known as Sodium Pyrosulfite. It is a preservative, antioxidant, and disinfectant.
As a preservative, it helps stabilize cosmetic formulas without affecting their color or scent.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.