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Meditopics Huidreiniger op basis van Melkzuur pH 3,5 Versus Paula's Choice Calm Ultra-Gentle Cleanser

Meditopics Huidreiniger op basis van Melkzuur pH 3,5 Versus Paula's Choice Calm Ultra-Gentle Cleanser This lactic acid cream cleanser is formulated around Lactic Acid to exfoliate and smooth skin. This mild gel cleanser is made to cleanse while calming and soo

Meditopics Huidreiniger op basis van Melkzuur pH 3,5 Versus Paula's Choice Calm Ultra-Gentle Cleanser

This lactic acid cream cleanser is formulated around Lactic Acid to exfoliate and smooth skin.

This mild gel cleanser is made to cleanse while calming and soothing your skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Cocamidopropyl Betaine

Lactic Acid

PEG-8 Stearate

PEG-3 Distearate

Sodium Lactate

Hydroxyethylcellulose

Phenoxyethanol

Sodium Chloride

Glycerin

Ethylhexylglycerin

Parfum

Sodium Benzoate

Tocopherol

Glycine Soja Oil

Water, Cocamidopropyl Betaine, Lactic Acid, PEG-8 Stearate, PEG-3 Distearate, Sodium Lactate, Hydroxyethylcellulose, Phenoxyethanol, Sodium Chloride, Glycerin, Ethylhexylglycerin, Parfum, Sodium Benzoate, Tocopherol, Glycine Soja Oil

Sodium Cocoyl Glutamate

Caprylic/Capric Triglyceride

Sodium Laurylglucosides Hydroxypropylsulfonate

Cellulose Gum

Coco-Caprylate/Caprate

Hydroxyacetophenone

Inulin

Xanthan Gum

Sodium Phytate

Cellulose

Fructose

Glucose

Water, Sodium Cocoyl Glutamate, Glycerin, Caprylic/Capric Triglyceride, Cocamidopropyl Betaine, Sodium Laurylglucosides Hydroxypropylsulfonate, Cellulose Gum, Coco-Caprylate/Caprate, Hydroxyacetophenone, Inulin, Xanthan Gum, Ethylhexylglycerin, Sodium Phytate, Cellulose, Fructose, Glucose, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Cocamidopropyl Betaine is a fatty acid created by mixing similar compounds in coconut oil and dimethylaminopropylamine, a compound with two amino groups.

This ingredient is a surfactant and cleanser. It helps gather the dirt, pollutants, and other impurities in your skin to be washed away. It also helps thicken a product and make the texture more creamy.

Being created from coconut oil means Cocamidopropyl Betaine is hydrating for the skin.

While Cocamidopropyl Betaine was believed to be an allergen, a study from 2012 disproved this. It found two compounds in unpure Cocamidopropyl Betaine to be the irritants: aminoamide and 3-dimethylaminopropylamine. High-grade and pure Cocamidopropyl Betaine did not induce allergic reactions during this study.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
  4. 04The way it works is fairly well mapped out:
  5. 05Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down o…
  6. 06The clinical backing is pretty solid too.
  7. 07A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at…
  8. 08A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
  9. 09On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
  10. 10This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
  11. 11Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
  12. 12Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  13. 13Topically, glycerin does several things at once:
  14. 14Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  15. 15Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  16. 16This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  17. 17Just know very high concentrations (>40%) can feel tacky in low humidity.
  18. 18Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  19. 19Glycine Soja Oil is a plant-derived oil from soybean seeds. Like other oils, it is rich in essential fatty acids (mostly linoleic and oleic) that support skin hydration and barrier function.
  20. 20The fatty acids are able to integrate into the lipid matrix of the stratum corneum to help soften skin and reduce water loss.
Source · skinsort.com
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Product index

Related product references

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Comparison edit

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