Skin science article
Missha Vita C Plus Spot Correcting & Firming Ampoule Versus Beauty of Joseon Light On Serum : Centella + Vita C
Missha Vita C Plus Spot Correcting & Firming Ampoule Versus Beauty of Joseon Light On Serum : Centella + Vita C This brightening ampoule is formulated around Niacinamide and 3-O-Ethyl Ascorbic Acid to fade the look of dark spots and soften the look of wrinkles
Missha Vita C Plus Spot Correcting & Firming Ampoule Versus Beauty of Joseon Light On Serum : Centella + Vita C
This brightening ampoule is formulated around Niacinamide and 3-O-Ethyl Ascorbic Acid to fade the look of dark spots and soften the look of wrinkles.
This brightening serum is formulated around Centella Asiatica Extract and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Glycyrrhiza Uralensis Root Extract
Hippophae Rhamnoides Water
Glycerin
Methylpropanediol
Butylene Glycol
Niacinamide
Diethoxyethyl Succinate
1,2-Hexanediol
Tocopheryl Acetate
Water
3-O-Ethyl Ascorbic Acid
Bifida Ferment Lysate
Tranexamic Acid
Sodium Polyacryloyldimethyl Taurate
Chlorella Vulgaris Extract
Glucose
Caprylic/Capric Triglyceride
Glycine Soja Oil
Fructooligosaccharides
Fructose
Arbutin
Hydrogenated Lecithin
Panthenol
Citrus Aurantium Dulcis Peel Oil
Xanthan Gum
Adenosine
Ethylhexylglycerin
Citric Acid
Polyquaternium-51
Ceramide NP
Citrus Grandis Peel Oil
Sodium Phytate
Eucalyptus Globulus Leaf Oil
Lavandula Angustifolia Oil
Sodium Citrate
Daucus Carota Sativa Root Extract
Beta-Carotene
Tocopherol
Hydrolyzed Collagen
Allantoin
Glyceryl Glucoside
Dipropylene Glycol
Palmitoyl Tripeptide-5
Caprylyl Glycol
Ascorbic Acid
Hyaluronic Acid
Acetyl Hexapeptide-8
Pentylene Glycol
Pvp
Laurdimonium Hydroxypropyl Hydrolyzed Wheat Protein
Hydrolyzed Hyaluronic Acid
Sodium Hyaluronate
Phytosterols
Ascorbyl Glucoside
Fullerenes
Limonene
Linalool
Glycyrrhiza Uralensis Root Extract, Hippophae Rhamnoides Water, Glycerin, Methylpropanediol, Butylene Glycol, Niacinamide, Diethoxyethyl Succinate, 1,2-Hexanediol, Tocopheryl Acetate, Water, 3-O-Ethyl Ascorbic Acid, Bifida Ferment Lysate, Tranexamic Acid, Sodium Polyacryloyldimethyl Taurate, Chlorella Vulgaris Extract, Glucose, Caprylic/Capric Triglyceride, Glycine Soja Oil, Fructooligosaccharides, Fructose, Arbutin, Hydrogenated Lecithin, Panthenol, Citrus Aurantium Dulcis Peel Oil, Xanthan Gum, Adenosine, Ethylhexylglycerin, Citric Acid, Polyquaternium-51, Ceramide NP, Citrus Grandis Peel Oil, Sodium Phytate, Eucalyptus Globulus Leaf Oil, Lavandula Angustifolia Oil, Sodium Citrate, Daucus Carota Sativa Root Extract, Beta-Carotene, Tocopherol, Hydrolyzed Collagen, Allantoin, Glyceryl Glucoside, Dipropylene Glycol, Palmitoyl Tripeptide-5, Caprylyl Glycol, Ascorbic Acid, Hyaluronic Acid, Acetyl Hexapeptide-8, Pentylene Glycol, Pvp, Laurdimonium Hydroxypropyl Hydrolyzed Wheat Protein, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Phytosterols, Ascorbyl Glucoside, Fullerenes, Limonene, Linalool
Centella Asiatica Extract
Propanediol
Betaine
Dicaprylyl Carbonate
Methyl Trimethicone
Cetyl Ethylhexanoate
Laminaria Japonica Extract
Eclipta Prostrata Leaf Extract
Phellodendron Amurense Bark Extract
Citrus Unshiu Peel Extract
Brassica Oleracea Acephala Leaf Extract
Hydrolyzed Gardenia Florida Extract
Cetearyl Alcohol
Dimethicone/Vinyl Dimethicone Crosspolymer
Silica
Bisabolol
Potassium Cetyl Phosphate
Hydrolyzed Jojoba Esters
Cetearyl Olivate
Sorbitan Olivate
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer
Polyglyceryl-10 Myristate
Beta-Glucan
Sorbitan Isostearate
Maltodextrin
Arginine
Carbomer
Ascorbic Acid Polypeptide
Hydroxyacetophenone
Centella Asiatica Extract, 3-O-Ethyl Ascorbic Acid, Glycerin, Propanediol, Betaine, Dicaprylyl Carbonate, Methyl Trimethicone, Cetyl Ethylhexanoate, Panthenol, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Phellodendron Amurense Bark Extract, Citrus Unshiu Peel Extract, Brassica Oleracea Acephala Leaf Extract, Hydrolyzed Gardenia Florida Extract, Hydrogenated Lecithin, Cetearyl Alcohol, Water, Dimethicone/Vinyl Dimethicone Crosspolymer, Silica, Bisabolol, Potassium Cetyl Phosphate, Hydrolyzed Jojoba Esters, Cetearyl Olivate, Sorbitan Olivate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Xanthan Gum, Polyglyceryl-10 Myristate, Adenosine, Fructooligosaccharides, Beta-Glucan, Butylene Glycol, Sorbitan Isostearate, Hydrolyzed Hyaluronic Acid, Maltodextrin, Arginine, Carbomer, Ascorbic Acid Polypeptide, 1,2-Hexanediol, Hydroxyacetophenone, Ethylhexylglycerin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
3-O-Ethyl Ascorbic Acid is one of the most popular "stable" vitamin C derivatives in skincare.
Plain ascorbic acid is fantastic but notoriously fragile; it browns, oxidizes, and loses potency fast. So attaching an ethyl group to the third carbon of the molecule gives it some cool perks:
In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen.
The evidence is reasonably solid for a cosmetic ingredient; Liao and colleagues (2018) showed it's significantly more stable than ascorbic acid while still being effective.
A 2021 study by Zerbinati and colleagues tested a serum with 30% 3-O-ethyl-l-ascorbic acid and 1% lactic acid significantly increased collagen production, reduced UVB-induced DNA damage, and decreased melanin on a reconstructed pigmented skin model.
Typical real world usage sits around 0.5-5% (and 1-2% is common for daily serums).
Amounts up to 30% have been shown to be non-irritating on human skin samples, but two isolated cases reported allergic contact dermatitis so a patch test is sensible if you have reactive skin.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Fructooligosaccharides (FOS) are a type of prebiotic sugar with humectant and skin conditioning properties. As a humectant, they help attract and hold moisture in the skin.
FOS essentially acts as a food source for the "good" bacteria on your skin and make it harder for "bad" bacteria to thrive. A 2022 study using a reconstructured human skin model found that just 1% of FOS was enough to shift the bacteria balance in favor of beneficial species. This suggests it could help support a healthier skin microbiome over time.
This ingredient has a low sensitization risk and testing shows it does not classify as a skin irritant or sensitizer.
FOS are usually produced from sugar beets and can also be found in foods like bananas, garlic, and onions.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.
It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.
Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.
Most formulations will combine all sizes to get the best of both worlds.
Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.