Naturium Glycolic Acid Resurfacing Gel 10% Versus Paula's Choice RESIST Advanced Smoothing Treatment 10% AHA

Naturium Glycolic Acid Resurfacing Gel 10% Versus Paula's Choice RESIST Advanced Smoothing Treatment 10% AHA

This smoothing serum is formulated around Glycolic Acid to refine skin texture and brighten dull-looking skin.

This smoothing treatment is formulated around Glycolic Acid and Lactic Acid to refine skin texture and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycolic Acid

Propanediol

Sodium Hydroxide

Glycerin

Polyacrylate Crosspolymer-11

Vaccinium Myrtillus Fruit/Leaf Extract

Saccharum Officinarum Extract

Citrus Aurantium Dulcis Fruit Extract

Citrus Limon Fruit Extract

Acer Saccharum Extract

Microcitrus Australis Fruit Extract

Sodium Hyaluronate

Hydroxyacetophenone

Phenoxyethanol

Hydroxyethylcellulose

Tocopheryl Acetate

Ethylhexylglycerin

Disodium EDTA

Tocopherol

Water, Glycolic Acid, Propanediol, Sodium Hydroxide, Glycerin, Polyacrylate Crosspolymer-11, Vaccinium Myrtillus Fruit/Leaf Extract, Saccharum Officinarum Extract, Citrus Aurantium Dulcis Fruit Extract, Citrus Limon Fruit Extract, Acer Saccharum Extract, Microcitrus Australis Fruit Extract, Sodium Hyaluronate, Hydroxyacetophenone, Phenoxyethanol, Hydroxyethylcellulose, Tocopheryl Acetate, Ethylhexylglycerin, Disodium EDTA, Tocopherol

Butylene Glycol

Lactic Acid

Caprylic/Capric Triglyceride

Malic Acid

Tartaric Acid

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Ceramide Ng

Salicylic Acid

Glycyrrhiza Glabra Root

Camellia Sinensis Leaf Extract

Punica Granatum Extract

Lycium Barbarum Fruit Extract

Vitis Vinifera Seed Extract

Sambucus Nigra Fruit Extract

Camellia Oleifera Leaf

Chamomilla Recutita Flower Extract

Peucedanum Graveolens Extract

Allantoin

Adenosine

Hydrogenated Lecithin

Bisabolol

Polyquaternium-10

Xanthan Gum

Carbomer

Polysorbate 20

Sodium Bicarbonate

Aminomethyl Propanol

Benzyl Alcohol

Water, Butylene Glycol, Glycolic Acid, Glycerin, Lactic Acid, Caprylic/Capric Triglyceride, Malic Acid, Tartaric Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide Ng, Salicylic Acid, Glycyrrhiza Glabra Root, Camellia Sinensis Leaf Extract, Punica Granatum Extract, Lycium Barbarum Fruit Extract, Vitis Vinifera Seed Extract, Sambucus Nigra Fruit Extract, Camellia Oleifera Leaf, Chamomilla Recutita Flower Extract, Peucedanum Graveolens Extract, Allantoin, Adenosine, Hydrogenated Lecithin, Bisabolol, Polyquaternium-10, Xanthan Gum, Carbomer, Polysorbate 20, Sodium Bicarbonate, Sodium Hydroxide, Aminomethyl Propanol, Phenoxyethanol, Benzyl Alcohol

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glycolic Acid is arguably the most famous alpha hydroxy acid (AHA) with tons of research backing its benefits.

It is found naturally in sugar cane but the form used in skincare is usually synthetic for purity and stability.

Glycolic acid removes the top layer of dead skin cells to allow newer and fresher ones to emerge.

AHAs work by breaking down the structural “glue” that holds old skin cells in place. When that buildup is gone, your skin can renew itself more efficiently.

Research also shows glycolic acid stimulates collagen production, helping to firm and thicken the skin over time. This is one of its biggest advantages over other AHAs.

Overall, glycolic acid helps with:

Fun fact: Glycolic acid boosts skin hydration by helping it produce molecules that increase hyaluronic acid naturally.

To work best, glycolic acid products should have a pH between 3-4 (that’s where exfoliation is most effective but still gentle on skin).

The pH and concentration of a product are key to its effectiveness:

It is normal to feel a slight stinging sensation when using glycolic acid. This usually fades as your skin adjusts.

Because glycolic acid has the smallest molecular size in the AHA family, it can penetrate deeper, which enhances its effectiveness but also makes it more likely to irritate sensitive skin.

If your skin is very sensitive or prone to rosacea, glycolic acid may be too strong; in that case, try milder options like lactic acid or a PHA instead.

Recent studies suggest glycolic acid might even help protect against UV damage. But don’t skip sunscreen! Freshly exfoliated skin is more sensitive to the sun.

Glycolic acid is a skincare superstar. It smooths, brightens, hydrates, and firms the skin. Unless you’re highly sensitive, it’s well worth adding to your routine.

Read more about some other popular AHA's here:

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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