Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Naturium Quadruple Hyaluronic Acid Serum 5% Versus Cocokind Ceramide Barrier Serum

Naturium Quadruple Hyaluronic Acid Serum 5% Versus Cocokind Ceramide Barrier Serum This hydrating serum is formulated around Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier. This barrier-repair serum is formula

Naturium Quadruple Hyaluronic Acid Serum 5% Versus Cocokind Ceramide Barrier Serum

This hydrating serum is formulated around Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

This barrier-repair serum is formulated around Aloe Barbadensis Leaf Juice and Beta-Glucan to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Propanediol

Hydrolyzed Hyaluronic Acid

Sodium Hyaluronate

Apricot Kernel Oil Polyglyceryl-6 Esters

Polyglyceryl-6 Oleate

Caprylyl Glycol

Polyglyceryl-10 Oleate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Magnolol

Kaempferol

Tetrahexyldecyl Ascorbate

Glycolipids

Glycine Soja Sterols

Tocopheryl Acetate

Phenoxyethanol

Sorbitan Palmate

Potassium Sorbate

Sodium Hydroxide

Glyceryl Polyacrylate

Xanthan Gum

Hexylene Glycol

Water, Glycerin, Propanediol, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Apricot Kernel Oil Polyglyceryl-6 Esters, Polyglyceryl-6 Oleate, Caprylyl Glycol, Polyglyceryl-10 Oleate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Magnolol, Kaempferol, Tetrahexyldecyl Ascorbate, Glycolipids, Glycine Soja Sterols, Tocopheryl Acetate, Phenoxyethanol, Sorbitan Palmate, Potassium Sorbate, Sodium Hydroxide, Glyceryl Polyacrylate, Xanthan Gum, Hexylene Glycol

Aloe Barbadensis Leaf Juice

Simmondsia Chinensis Seed Oil

Squalane

Beta-Glucan

Lysolecithin

Sclerotium Gum

Pullulan

Ceramide NP

Ceramide Ns

Ceramide AP

Ceramide Eos

Ceramide EOP

Sodium Levulinate

Sodium Anisate

Tocopherol

Cetyl Alcohol

Ceteareth-25

Silica

Caprooyl Phytosphingosine

Caprooyl Sphingosine

Cholesterol

Helianthus Annuus Seed Oil

Glyceryl Caprylate

Sodium Benzoate

Ethylhexylglycerin

1,2-Hexanediol

Citric Acid

Behenic Acid

Aloe Barbadensis Leaf Juice, Water, Propanediol, Glycerin, Simmondsia Chinensis Seed Oil, Squalane, Beta-Glucan, Lysolecithin, Sclerotium Gum, Pullulan, Xanthan Gum, Ceramide NP, Ceramide Ns, Ceramide AP, Ceramide Eos, Ceramide EOP, Sodium Levulinate, Sodium Anisate, Tocopherol, Cetyl Alcohol, Caprylyl Glycol, Ceteareth-25, Silica, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Cholesterol, Helianthus Annuus Seed Oil, Glyceryl Caprylate, Phenoxyethanol, Sodium Benzoate, Ethylhexylglycerin, 1,2-Hexanediol, Citric Acid, Behenic Acid

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Glycerin
  3. 03Hydroxyethylpiperazine Ethane Sulfonic Acid
  4. 04Sodium Hyaluronate
  5. 05PEG-60
  6. 06Hydrogenated Castor Oil
  7. 07Secale Cereale Seed Extract
  8. 08Calcium Pantothenate
  9. 09Dipeptide Diaminobutyroyl Benzylamide Diacetate
  10. 10Ascorbyl Glucoside
  11. 11Disodium EDTA
  12. 12Pentylene Glycol
  13. 13Phenoxyethanol
  14. 14Chlorphenesin
  15. 15Water, Glycerin, Hydroxyethylpiperazine Ethane Sulfonic Acid, Sodium Hyaluronate, PEG-60, Hydrogenated Castor Oil, Secale Cereale Seed Extract, Calcium Pantothenate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Ascorbyl Glucoside, Disodium EDTA,…
  16. 163-O-Ethyl Ascorbic Acid
  17. 17Propanediol
  18. 18Palmitoyl Tripeptide-5
  19. 19Tocopherol
  20. 20Glycyrrhiza Glabra Root Extract
Source · skinsort.com
02

Product index

Related product references

Product

Omnilux Hyaluronic Acid Serum

Omnilux Hyaluronic Acid Serum Ingredients in Omnilux Hyaluronic Acid Serum explained: benefits, concerns, and detailed analysis of 21 ingredients including Water, Glycerin, and Propylene Gl…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side

04

Ask the journal

Related questions

01How to Apply Face Serums

Skincare rules can get confusing, but when it comes to application the general rule of thumb is to pay attention to the product’s consistency. “Apply the lightest, thinnest product first and the heaviest, and more dense products last, since thinner products can’t penetrate thicker products,”says Dr. Lewis. After cleansing the face and following up with a toner, let the skin dry before using a serum. You can layer different serums on top of each other or opt for a product that has a precise mix of multiple hero ingredients, such as hyaluronic acid and vitamin C.

Source · www.skincare.com
02When and How to Use Hyaluronic Acid in Your Routine

Products with hyaluronic acid can be used in the morning or at night (or both!). Applying the hydrating ingredient at night will restore your skin’s resilience while you sleep, and applying it in the morning will leave your skin feeling plump, hydrated and ready for makeup. Hyaluronic acid is great at providing topical hydration when it’s introduced into a balanced skincare routine. According to Dr. King, it’s important to pair your hyaluronic acid products with an emollient or occlusive moisturizer to lock in hydration.

Source · www.skincare.com