Skin science article
Neogen Real Hyal Panthenol Serum Versus Beauty of Joseon Glow Serum: Propolis + Niacinamide
Neogen Real Hyal Panthenol Serum Versus Beauty of Joseon Glow Serum: Propolis + Niacinamide This hydrating serum is formulated around Panthenol and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier. This acne serum is formulated around Propoli
Neogen Real Hyal Panthenol Serum Versus Beauty of Joseon Glow Serum: Propolis + Niacinamide
This hydrating serum is formulated around Panthenol and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.
This acne serum is formulated around Propolis Extract and Niacinamide to clear breakouts and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Panthenol 5%
Butylene Glycol
Propanediol
1,2-Hexanediol
Polyglyceryl-10 Laurate
Sodium Hyaluronate
Carbomer
Ethylhexylglycerin
Tromethamine
Morinda Citrifolia Leaf Extract
Morinda Citrifolia Flower Extract
Coccinia Indica Fruit Extract
Solanum Melongena Fruit Extract
Glycerin
Ocimum Sanctum Leaf Extract
Xanthan Gum
Curcuma Longa Root Extract
Corallina Officinalis Extract
Caprylyl Glycol
Hydrogenated Lecithin
Sodium Ascorbyl Phosphate
Glucose
Niacinamide
Chondrus Crispus Extract
Hydroxypropyltrimonium Hyaluronate
Biotin
Pyridoxine
Folic Acid
Hydrolyzed Hyaluronic Acid
Sodium Acetylated Hyaluronate
Cyanocobalamin
Tocopherol
Hyaluronic Acid
Sodium Hyaluronate Crosspolymer
Hydrolyzed Sodium Hyaluronate
Riboflavin
Thiamine Hcl
Linoleic Acid
Potassium Hyaluronate
Beta-Carotene
Water, Panthenol 5%, Butylene Glycol, Propanediol, 1,2-Hexanediol, Polyglyceryl-10 Laurate, Sodium Hyaluronate, Carbomer, Ethylhexylglycerin, Tromethamine, Morinda Citrifolia Leaf Extract, Morinda Citrifolia Flower Extract, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Glycerin, Ocimum Sanctum Leaf Extract, Xanthan Gum, Curcuma Longa Root Extract, Corallina Officinalis Extract, Caprylyl Glycol, Hydrogenated Lecithin, Sodium Ascorbyl Phosphate, Glucose, Niacinamide, Chondrus Crispus Extract, Hydroxypropyltrimonium Hyaluronate, Biotin, Pyridoxine, Folic Acid, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Cyanocobalamin, Tocopherol, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Riboflavin, Thiamine Hcl, Linoleic Acid, Potassium Hyaluronate, Beta-Carotene
Propolis Extract
Dipropylene Glycol
Melia Azadirachta Flower Extract
Melia Azadirachta Leaf Extract
Theobroma Cacao Seed Extract
Melaleuca Alternifolia Leaf Extract
Centella Asiatica Extract
Lotus Corniculatus Seed Extract
Calophyllum Inophyllum Seed Oil
Betaine Salicylate
Sodium Polyacryloyldimethyl Taurate
Dextrin
Pentylene Glycol
Octanediol
Propolis Extract, Dipropylene Glycol, Glycerin, Butylene Glycol, Water, Niacinamide, 1,2-Hexanediol, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Sodium Hyaluronate, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Theobroma Cacao Seed Extract, Melaleuca Alternifolia Leaf Extract, Centella Asiatica Extract, Corallina Officinalis Extract, Lotus Corniculatus Seed Extract, Calophyllum Inophyllum Seed Oil, Betaine Salicylate, Sodium Polyacryloyldimethyl Taurate, Tromethamine, Polyglyceryl-10 Laurate, Caprylyl Glycol, Ethylhexylglycerin, Dextrin, Pentylene Glycol, Octanediol, Tocopherol, Xanthan Gum, Carbomer
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Corallina Officinalis Extract is from the red seaweed, Corallina Officinalis. This seaweed is found all over the world but is most common in the rocky shores of Great Britain and Ireland.
Corallina Officinalis Extract contains antioxidant and emollient properties.
Extracted polysaccharides, galactose and xylose, in red algae showed antioxidant activity. Antioxidants help with anti-aging by neutralizing free-radical molecules. Free-radical molecules may damage your skin cells and DNA. Galactose is also a PHA.
Corallina Officinalis is structurally similar to coral due to its high calcium content.
Curcuma Longa Root Extract comes from the rhizome (underground stem) of the turmeric plant.
While the official EU Cosing Database lists this ingredient as a fragrance, it actually does more than give products a scent.
This ingredient contains a group of yellow pigments called curcuminoids (mostly curcumin) that give it genuine antioxidant and anti-inflammatory activity in skin.
Reviews of topical clinical studies have found turmeric/curcumin to be generally well-tolerated and useful across conditions like eczema and mild inflammation.
One thing working in its favor is that curcumin barely penetrates; in lab skin-permeation testing, the curcuminoids mostly stayed in the outermost layer of skin. This is a good thing because its soothing and antioxidant activity is a surface-level job anyway.
At this time, industry data shows there's no single "correct" cosmetic percentage. It's used across a wide range depending on the product and varies from tiny fractions of a percent up to a few percent.
Allergy-wise, curcumin is a documented (but uncommon) contact allergen. It can also cross react with related plants, so anyone with a turmeric/ginger/cinnamon allergy or reactive skin should patch test first.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Ocimum Sanctum Leaf Extract comes from the Holy Basil plant. Holy Basil is native to India.
Holy Basil is rich in antioxidants due to its high romarinic acid, ferulic acid, and rutin content. This gives it skin brightening and soothing properties.
While Holy Basil has many claims to help fight acne, more research is needed.
One thing to note is the presence of tannins; tannins are naturally found in nature. However, this compound may be skin-sensitizing.
Polyglyceryl-10 Laurate is a cleansing agent and emulsifier.
It rounds up dirt, oil, and grime, so they can be rinsed off easily as a cleanser.
On the emulsifier side, it keeps your formula smooth and well-mixed by playing peacekeeper for ingredients that don't naturally get along (like oil and water).
Because it has a C12 (lauric acid) fatty acid chain, this ingredient can potentially feed the Malassezia yeast that causes fungal acne. The Malassezia yeast prefers esters with C11-C24 fatty acids.
This ingredient is an ester of lauric acid and Polyglycerin-10.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.
It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.
This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.
Concentration use ranges from 0.1-1.0% depending on the formula.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.