Skin science article
NeoStrata Dermal Replenishment Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer
NeoStrata Dermal Replenishment Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer This anti-aging moisturizer is formulated around Maltobionic Acid and Acetyl Glucosamine to soften the look of wrinkles. This anti-aging night moisturizer is formulate
NeoStrata Dermal Replenishment Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer
This anti-aging moisturizer is formulated around Maltobionic Acid and Acetyl Glucosamine to soften the look of wrinkles.
This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Maltobionic Acid
Acetyl Glucosamine
Octyldodecyl Neopentanoate
Steareth-2
C12-15 Alkyl Benzoate
Butyrospermum Parkii Butter
Octyldodecanol
Steareth-20
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Isostearic Acid
Cyclopentasiloxane
Acetyl Tyrosinamide
Saccharide Isomerate
Cyclohexasiloxane
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Vitis Vinifera Seed Extract
Sodium PCA
Serine
Glycine
Alanine
Lysine
Arginine
Threonine
Proline
Cetyl Alcohol
Propylene Glycol
Betaine
Sorbitol
Isopropyl Myristate
Glutamic Acid
Butylene Glycol
Polysorbate 60
Sorbitan Isostearate
Carbomer
Polysorbate 20
Ammonium Hydroxide
Disodium EDTA
Caprylyl Glycol
Sodium Bisulfite
Xanthan Gum
Phenoxyethanol
Chlorphenesin
Methyldihydrojasmonate
Isobutyl Methyl Tetrahydropyranol
Ethylene Brassylate
Methyl Decenol
CI 14700
CI 19140
Water, Glycerin, Maltobionic Acid, Acetyl Glucosamine, Octyldodecyl Neopentanoate, Steareth-2, C12-15 Alkyl Benzoate, Butyrospermum Parkii Butter, Octyldodecanol, Steareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isostearic Acid, Cyclopentasiloxane, Acetyl Tyrosinamide, Saccharide Isomerate, Cyclohexasiloxane, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Vitis Vinifera Seed Extract, Sodium PCA, Serine, Glycine, Alanine, Lysine, Arginine, Threonine, Proline, Cetyl Alcohol, Propylene Glycol, Betaine, Sorbitol, Isopropyl Myristate, Glutamic Acid, Butylene Glycol, Polysorbate 60, Sorbitan Isostearate, Carbomer, Polysorbate 20, Ammonium Hydroxide, Disodium EDTA, Caprylyl Glycol, Sodium Bisulfite, Xanthan Gum, Phenoxyethanol, Chlorphenesin, Methyldihydrojasmonate, Isobutyl Methyl Tetrahydropyranol, Ethylene Brassylate, Methyl Decenol, CI 14700, CI 19140
Dimethicone
Tapioca Starch
Dimethicone Crosspolymer
Retinol
Retinyl Propionate
Niacinamide
Palmitoyl Pentapeptide-4
Polyacrylamide
C13-14 Isoparaffin
DMDM Hydantoin
Laureth-4
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Laureth-7
Dimethiconol
Polymethylsilsesquioxane
Aminomethyl Propanol
Titanium Dioxide
Iodopropynyl Butylcarbamate
Caprylic/Capric Triglyceride
Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!