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NeoStrata Dermal Replenishment Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

NeoStrata Dermal Replenishment Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer This anti-aging moisturizer is formulated around Maltobionic Acid and Acetyl Glucosamine to soften the look of wrinkles. This anti-aging night moisturizer is formulate

NeoStrata Dermal Replenishment Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

This anti-aging moisturizer is formulated around Maltobionic Acid and Acetyl Glucosamine to soften the look of wrinkles.

This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Maltobionic Acid

Acetyl Glucosamine

Octyldodecyl Neopentanoate

Steareth-2

C12-15 Alkyl Benzoate

Butyrospermum Parkii Butter

Octyldodecanol

Steareth-20

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Isostearic Acid

Cyclopentasiloxane

Acetyl Tyrosinamide

Saccharide Isomerate

Cyclohexasiloxane

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Vitis Vinifera Seed Extract

Sodium PCA

Serine

Glycine

Alanine

Lysine

Arginine

Threonine

Proline

Cetyl Alcohol

Propylene Glycol

Betaine

Sorbitol

Isopropyl Myristate

Glutamic Acid

Butylene Glycol

Polysorbate 60

Sorbitan Isostearate

Carbomer

Polysorbate 20

Ammonium Hydroxide

Disodium EDTA

Caprylyl Glycol

Sodium Bisulfite

Xanthan Gum

Phenoxyethanol

Chlorphenesin

Methyldihydrojasmonate

Isobutyl Methyl Tetrahydropyranol

Ethylene Brassylate

Methyl Decenol

CI 14700

CI 19140

Water, Glycerin, Maltobionic Acid, Acetyl Glucosamine, Octyldodecyl Neopentanoate, Steareth-2, C12-15 Alkyl Benzoate, Butyrospermum Parkii Butter, Octyldodecanol, Steareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isostearic Acid, Cyclopentasiloxane, Acetyl Tyrosinamide, Saccharide Isomerate, Cyclohexasiloxane, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Vitis Vinifera Seed Extract, Sodium PCA, Serine, Glycine, Alanine, Lysine, Arginine, Threonine, Proline, Cetyl Alcohol, Propylene Glycol, Betaine, Sorbitol, Isopropyl Myristate, Glutamic Acid, Butylene Glycol, Polysorbate 60, Sorbitan Isostearate, Carbomer, Polysorbate 20, Ammonium Hydroxide, Disodium EDTA, Caprylyl Glycol, Sodium Bisulfite, Xanthan Gum, Phenoxyethanol, Chlorphenesin, Methyldihydrojasmonate, Isobutyl Methyl Tetrahydropyranol, Ethylene Brassylate, Methyl Decenol, CI 14700, CI 19140

Dimethicone

Tapioca Starch

Dimethicone Crosspolymer

Retinol

Retinyl Propionate

Niacinamide

Palmitoyl Pentapeptide-4

Polyacrylamide

C13-14 Isoparaffin

DMDM Hydantoin

Laureth-4

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Laureth-7

Dimethiconol

Polymethylsilsesquioxane

Aminomethyl Propanol

Titanium Dioxide

Iodopropynyl Butylcarbamate

Caprylic/Capric Triglyceride

Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.

It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03C13-14 Isoparaffin is a synthetic emollient, solvent, and thickening agent. It helps soften skin and improves spreadability without leaving a greasy residue.
  4. 04This ingredient has been found to be non-sensitizing and safe for use in cosmetics.
  5. 05Two things floating around online that cause fear-mongering:
  6. 06There's one scary-sounding study related to kidney tumors in male rats; this depends on a protein called alpha-2u-globulin that binds the ingredient and clogs up kidney cells. Female rats barely make this protein, and humans don't make it at all so …
  7. 07The other thing you'll see is 1,4-dioxane being a trace byproduct that can form during manufacturing of petroleum-derived ingredients. This is a real, but heavily managed/monitored issue. This byproduct is removed through purification steps before t…
  8. 08One last thing to note: this ingredient is a pure hydrocarbon with no fatty-acid or ester chains for Malassezia to feed on, so it's considered fungal acne safe.
  9. 09Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
  10. 10What it does:
  11. 11Dimethicone comes in different viscosities:
  12. 12Depending on the viscosity, dimethicone has different properties.
  13. 13Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
  14. 14This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
  15. 15Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
  16. 16Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
  17. 17This ingredient mainly works behind the scenes and helps with:
  18. 18On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
  19. 19One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too st…
  20. 20Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
Source · skinsort.com
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Comparison edit

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