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Skin science article

Neutrogena Extra Gentle Cleanser Versus Paula's Choice Skin Balancing Oil-Reducing Cleanser

Neutrogena Extra Gentle Cleanser Versus Paula's Choice Skin Balancing Oil-Reducing Cleanser This mild cream cleanser is made to cleanse without leaving your skin tight or dry. What's inside Benefits Concerns Ingredients Side-by-side Water Glycerin Cetearyl Alc

Neutrogena Extra Gentle Cleanser Versus Paula's Choice Skin Balancing Oil-Reducing Cleanser

This mild cream cleanser is made to cleanse without leaving your skin tight or dry.

What's inside

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Cetearyl Alcohol

Polyglyceryl-10 Laurate

Phenoxyethanol

Cetearyl Glucoside

Caprylyl Glycol

Carbomer

Sodium Hydroxide

Ethylhexylglycerin

Water, Glycerin, Cetearyl Alcohol, Polyglyceryl-10 Laurate, Phenoxyethanol, Cetearyl Glucoside, Caprylyl Glycol, Carbomer, Sodium Hydroxide, Ethylhexylglycerin

Sodium Cocoyl Isethionate

Sodium Lauroamphoacetate

Stearic Acid

Glycol Distearate

Helianthus Annuus Seed Oil

Acrylates Copolymer

Aloe Barbadensis Leaf Extract

Sodium Chloride

Xanthan Gum

Hexylene Glycol

Disodium EDTA

Water, Sodium Cocoyl Isethionate, Sodium Lauroamphoacetate, Stearic Acid, Glycerin, Glycol Distearate, Helianthus Annuus Seed Oil, Acrylates Copolymer, Cetearyl Alcohol, Aloe Barbadensis Leaf Extract, Sodium Chloride, Sodium Hydroxide, Xanthan Gum, Caprylyl Glycol, Hexylene Glycol, Disodium EDTA, Phenoxyethanol

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Butyl Methoxydibenzoylmethane 3%
  2. 02Homosalate 15%
  3. 03Ethylhexyl Salicylate 5%
  4. 04Octocrylene 10%
  5. 05Water
  6. 06Polymethylsilsesquioxane
  7. 07Glycerin
  8. 08Dimethicone
  9. 09Poly C10-30 Alkyl Acrylate
  10. 10Styrene/Acrylates Copolymer
  11. 11Silica
  12. 12Caprylyl Methicone
  13. 13Acrylates/Dimethicone Copolymer
  14. 14Diethylhexyl Syringylidenemalonate
  15. 15PEG-100 Stearate
  16. 16Glyceryl Stearate
  17. 17Phenoxyethanol
  18. 18Potassium Cetyl Phosphate
  19. 19Tocopherol
  20. 20Caprylyl Glycol
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side