Skin science article
Neutrogena Hydro Boost Gel Cream Versus Naturium Multi-Peptide Moisturizer
Neutrogena Hydro Boost Gel Cream Versus Naturium Multi-Peptide Moisturizer This barrier-repair moisturizer is formulated around Sodium Hyaluronate to strengthen the skin barrier and hydrate skin. This anti-aging moisturizer is formulated around Palmitoyl Tripe
Neutrogena Hydro Boost Gel Cream Versus Naturium Multi-Peptide Moisturizer
This barrier-repair moisturizer is formulated around Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.
This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-5 and Palmitoyl Tripeptide-1 to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dimethicone
Cetearyl Olivate
Sorbitan Olivate
Sodium Hyaluronate
Serine
Glycine
Alanine
Threonine
Arginine
Proline
Lysine Hcl
Glutamic Acid
Sodium PCA
PCA
Sodium Lactate
Urea
Sodium Chloride
Citric Acid
Betaine
Allantoin
Fructose
Maltose
Trehalose
Glucose
Pentylene Glycol
Synthetic Beeswax
Polyacrylate Crosspolymer-6
Dimethicone Crosspolymer
Dimethiconol
Ethylhexylglycerin
Caprylyl Glycol
Sodium Hydroxide
Water, Glycerin, Dimethicone, Cetearyl Olivate, Sorbitan Olivate, Sodium Hyaluronate, Serine, Glycine, Alanine, Threonine, Arginine, Proline, Lysine Hcl, Glutamic Acid, Sodium PCA, PCA, Sodium Lactate, Urea, Sodium Chloride, Citric Acid, Betaine, Allantoin, Fructose, Maltose, Trehalose, Glucose, Pentylene Glycol, Synthetic Beeswax, Polyacrylate Crosspolymer-6, Dimethicone Crosspolymer, Dimethiconol, Ethylhexylglycerin, Caprylyl Glycol, Sodium Hydroxide
Simmondsia Chinensis Seed Oil
Squalane
Glyceryl Stearate
Cetyl Alcohol
Niacinamide
Stearyl Alcohol
Palmitoyl Tripeptide-5
Pantolactone
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Hydrolyzed Plukenetia Volubilis Seed Extract
Dunaliella Salina Extract
3-O-Ethyl Ascorbic Acid
Panthenol
Caryodendron Orinocense Seed Oil
Honokiol
Magnolol
Palmitic Acid
Sorbitan Oleate
Aluminum Starch Octenylsuccinate
Hydroxyacetophenone
Stearic Acid
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Polyglyceryl-6 Laurate
1,2-Hexanediol
Boron Nitride
Polyglyceryl-10 Oleate
Isohexadecane
Butylene Glycol
Chlorphenesin
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Tocopheryl Acetate
Polysorbate 80
Sorbitan Palmitate
Sodium Benzoate
Carbomer
Phenoxyethanol
Polysorbate 20
Potassium Sorbate
Water, Glycerin, Dimethicone, Simmondsia Chinensis Seed Oil, Squalane, Glyceryl Stearate, Cetyl Alcohol, Niacinamide, Stearyl Alcohol, Palmitoyl Tripeptide-5, Pantolactone, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Plukenetia Volubilis Seed Extract, Dunaliella Salina Extract, Sodium Hyaluronate, 3-O-Ethyl Ascorbic Acid, Panthenol, Caryodendron Orinocense Seed Oil, Honokiol, Magnolol, Palmitic Acid, Sorbitan Oleate, Aluminum Starch Octenylsuccinate, Hydroxyacetophenone, Stearic Acid, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Polyglyceryl-6 Laurate, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Polyglyceryl-10 Oleate, Isohexadecane, Butylene Glycol, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, Polysorbate 80, Sorbitan Palmitate, Sodium Hydroxide, Sodium Benzoate, Carbomer, Sodium Lactate, Phenoxyethanol, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Potassium Sorbate
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.
This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
High percentages of Sodium Lactate can have an exfoliating effect.
Fun fact: Sodium Lactate is produced from fermented sugar.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!