Neutrogena Hydro Boost Hyaluronic Acid Serum Versus Neutrogena Hydro Boost Hydrating Serum

Neutrogena Hydro Boost Hyaluronic Acid Serum Versus Neutrogena Hydro Boost Hydrating Serum

This hydrating serum is formulated around Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

This hydrating serum is formulated around Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Butylene Glycol

Pentylene Glycol

Chondrus Crispus

Hydrolyzed Hyaluronic Acid

Sodium Hyaluronate

Panthenol

Trehalose

1,2-Hexanediol

Faex

Agar

Xylitylglucoside

Anhydroxylitol

Xylitol

Caprylyl Glycol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Xanthan Gum

Potassium Chloride

Disodium EDTA

Citric Acid

Sodium Hydroxide

Chlorphenesin

Phenoxyethanol

CI 77007

CI 77891

Mica

Water, Glycerin, Butylene Glycol, Pentylene Glycol, Chondrus Crispus, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Panthenol, Trehalose, 1,2-Hexanediol, Faex, Agar, Xylitylglucoside, Anhydroxylitol, Xylitol, Caprylyl Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Potassium Chloride, Disodium EDTA, Citric Acid, Sodium Hydroxide, Chlorphenesin, Phenoxyethanol, CI 77007, CI 77891, Mica

Dimethicone

Neopentyl Glycol Diheptanoate

Aluminum Starch Octenylsuccinate

Isododecane

Dimethiconol

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Ethylhexylglycerin

Benzyl Alcohol

Sodium Lactate

Cetearyl Olivate

Bisabolol

Sorbitan Olivate

Sodium PCA

Parfum

Sorbitol

Chondrus Crispus Extract

Proline

Portulaca Oleracea Extract

Propylene Glycol

Magnesium Aspartate

Zinc Gluconate

Copper Gluconate

Water, Glycerin, Dimethicone, Butylene Glycol, Neopentyl Glycol Diheptanoate, Aluminum Starch Octenylsuccinate, Isododecane, Dimethiconol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Ethylhexylglycerin, Benzyl Alcohol, Sodium Lactate, Cetearyl Olivate, Bisabolol, Chlorphenesin, Sorbitan Olivate, Sodium PCA, Parfum, Sodium Hyaluronate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sorbitol, Chondrus Crispus Extract, Sodium Hydroxide, Proline, Portulaca Oleracea Extract, Propylene Glycol, Citric Acid, Magnesium Aspartate, Zinc Gluconate, Copper Gluconate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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