Neutrogena Hydro Boost Hydrating Serum Versus Naturium Quadruple Hyaluronic Acid Serum 5%

Neutrogena Hydro Boost Hydrating Serum Versus Naturium Quadruple Hyaluronic Acid Serum 5%

This hydrating serum is formulated around Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

This hydrating serum is formulated around Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dimethicone

Butylene Glycol

Neopentyl Glycol Diheptanoate

Aluminum Starch Octenylsuccinate

Isododecane

Dimethiconol

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Ethylhexylglycerin

Benzyl Alcohol

Sodium Lactate

Cetearyl Olivate

Bisabolol

Chlorphenesin

Sorbitan Olivate

Sodium PCA

Parfum

Sodium Hyaluronate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sorbitol

Chondrus Crispus Extract

Sodium Hydroxide

Proline

Portulaca Oleracea Extract

Propylene Glycol

Citric Acid

Magnesium Aspartate

Zinc Gluconate

Copper Gluconate

Water, Glycerin, Dimethicone, Butylene Glycol, Neopentyl Glycol Diheptanoate, Aluminum Starch Octenylsuccinate, Isododecane, Dimethiconol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Ethylhexylglycerin, Benzyl Alcohol, Sodium Lactate, Cetearyl Olivate, Bisabolol, Chlorphenesin, Sorbitan Olivate, Sodium PCA, Parfum, Sodium Hyaluronate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sorbitol, Chondrus Crispus Extract, Sodium Hydroxide, Proline, Portulaca Oleracea Extract, Propylene Glycol, Citric Acid, Magnesium Aspartate, Zinc Gluconate, Copper Gluconate

Propanediol

Hydrolyzed Hyaluronic Acid

Apricot Kernel Oil Polyglyceryl-6 Esters

Polyglyceryl-6 Oleate

Caprylyl Glycol

Polyglyceryl-10 Oleate

Magnolol

Kaempferol

Tetrahexyldecyl Ascorbate

Glycolipids

Glycine Soja Sterols

Tocopheryl Acetate

Phenoxyethanol

Sorbitan Palmate

Potassium Sorbate

Glyceryl Polyacrylate

Xanthan Gum

Hexylene Glycol

Water, Glycerin, Propanediol, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Apricot Kernel Oil Polyglyceryl-6 Esters, Polyglyceryl-6 Oleate, Caprylyl Glycol, Polyglyceryl-10 Oleate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Magnolol, Kaempferol, Tetrahexyldecyl Ascorbate, Glycolipids, Glycine Soja Sterols, Tocopheryl Acetate, Phenoxyethanol, Sorbitan Palmate, Potassium Sorbate, Sodium Hydroxide, Glyceryl Polyacrylate, Xanthan Gum, Hexylene Glycol

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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