Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Neutrogena T/Sal® Therapeutic Shampoo-Scalp Build-Up Control Versus K18 Hair PEPTIDE PREP™ Clarifying Detox Shampoo

Neutrogena T/Sal® Therapeutic Shampoo-Scalp Build-Up Control Versus K18 Hair PEPTIDE PREP™ Clarifying Detox Shampoo What's inside Key Ingredients Benefits Concerns Ingredients Side-by-side Salicylic Acid 3% Water Sodium C14-16 Olefin Sulfonate Cocamidopropyl B

Neutrogena T/Sal® Therapeutic Shampoo-Scalp Build-Up Control Versus K18 Hair PEPTIDE PREP™ Clarifying Detox Shampoo

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Salicylic Acid 3%

Water

Sodium C14-16 Olefin Sulfonate

Cocamidopropyl Betaine

Sodium Chloride

Polyquaternium-22

Sodium Citrate

Hexylene Glycol

Sodium Lauroyl Sarcosinate

Linoleamidopropyl Pg-Dimonium Chloride Phosphate

Sodium Hydroxide

Citric Acid

Salicylic Acid 3%, Water, Sodium C14-16 Olefin Sulfonate, Cocamidopropyl Betaine, Sodium Chloride, Polyquaternium-22, Sodium Citrate, Hexylene Glycol, Sodium Lauroyl Sarcosinate, Linoleamidopropyl Pg-Dimonium Chloride Phosphate, Sodium Hydroxide, Citric Acid

Cocamidopropyl Hydroxysultaine

Salicylic Acid

Charcoal Powder

Sh-Oligopeptide-78

Panthenol

Glycerin

Sodium Phytate

Guar Hydroxypropyltrimonium Chloride

Caprylyl Glycol

Caprylhydroxamic Acid

Potassium Hydroxide

Parfum

Benzyl Salicylate

Limonene

Water, Sodium C14-16 Olefin Sulfonate, Cocamidopropyl Hydroxysultaine, Salicylic Acid, Charcoal Powder, Sh-Oligopeptide-78, Panthenol, Glycerin, Sodium Phytate, Guar Hydroxypropyltrimonium Chloride, Caprylyl Glycol, Caprylhydroxamic Acid, Citric Acid, Potassium Hydroxide, Sodium Hydroxide, Parfum, Benzyl Salicylate, Limonene

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Salicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.

Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.

Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.

Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.

It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.

While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.

If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.

Sodium C14-16 Olefin Sulfonate is a surfactant that helps water and oil mix so that dirt, sweat, sebum, and sunscreen can rinse away easily. It's not technically a sulfate, but behaves similarly in formulas.

What it does:

Sodium C14-16 Olefin Sulfonate is a strong cleansing surfactant and is much stronger than many mild cleansers. Because it works deeply, it can disrupt the skin's barrier. This can lead to dryness or irritation for those with sensitive skin.

Compared to gentler surfactants, it's effective but more likely to dry or irritate if not balanced with soothing ingredients.

CIR considers sodium α-olefin sulfonates (including C14-16) to be safe for use in rinse-off products when properly formulated. It is poorly absorbed through normal skin but absorption increases if the skin barrier is already damaged.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Coco-Glucoside
  3. 03Sodium Lauroyl Sarcosinate
  4. 04Glycerin
  5. 05Cocamidopropyl Betaine
  6. 06Epilobium Fleischeri Flower/Leaf/Stem Extract
  7. 07Niacinamide
  8. 08Citrus Aurantium Amara Flower Extract
  9. 09Lycium Barbarum Fruit Extract
  10. 10Hydrolyzed Oat Protein
  11. 11Porphyra Umbilicalis Extract
  12. 12Phyllanthus Emblica Fruit Extract
  13. 13Panthenol
  14. 14Hydrolyzed Glycosaminoglycans
  15. 15Sodium Hyaluronate
  16. 16Guar Hydroxypropyltrimonium Chloride
  17. 17Pantolactone
  18. 18Caesalpinia Spinosa Gum
  19. 19Sodium Benzoate
  20. 20Sodium Phytate
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side