Skin science article
Niod Survival 0 Versus Paula's Choice Resist Super Antioxidant Serum
Niod Survival 0 Versus Paula's Choice Resist Super Antioxidant Serum This anti-aging serum is formulated around Superoxide Dismutase and Astaxanthin to soften the look of wrinkles and calm redness. This anti-aging serum is formulated around Tetrahexyldecyl Asc
Niod Survival 0 Versus Paula's Choice Resist Super Antioxidant Serum
This anti-aging serum is formulated around Superoxide Dismutase and Astaxanthin to soften the look of wrinkles and calm redness.
This anti-aging serum is formulated around Tetrahexyldecyl Ascorbate and Palmitoyl Tripeptide-5 to soften the look of wrinkles and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Caprylic/Capric Triglyceride
Glycerin
Inulin
Alpha-Glucan Oligosaccharide
Solanum Lycopersicum Fruit Extract
Superoxide Dismutase
Dimethylmethoxy Chromanol
Xanthophylls
Astaxanthin
Pinus Pinaster Bark Extract
Polygonum Aviculare Extract
Alteromonas Ferment Extract
Padina Pavonica Thallus Extract
Arginine
Glycine
Alanine
Serine
Valine
Proline
Threonine
Isoleucine
Histidine
Phenylalanine
Aspartic Acid
PCA
Sodium PCA
Sodium Lactate
Piper Cubeba Fruit Extract
Haematococcus Pluvialis Extract
Squalane
Simmondsia Chinensis Seed Oil
Melanin
Sucrose
Lysolecithin
Tapioca Starch
Propanediol
Pentylene Glycol
Butylene Glycol
Polyglyceryl-10 Oleate
Polyglyceryl-10 Stearate
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Carbomer
Trisodium Ethylenediamine Disuccinate
Tromethamine
Triethanolamine
Ethoxydiglycol
Tocopherol
Potassium Sorbate
Sodium Benzoate
1,2-Hexanediol
Ethylhexylglycerin
Phenoxyethanol
Caprylyl Glycol
Water, Caprylic/Capric Triglyceride, Glycerin, Inulin, Alpha-Glucan Oligosaccharide, Solanum Lycopersicum Fruit Extract, Superoxide Dismutase, Dimethylmethoxy Chromanol, Xanthophylls, Astaxanthin, Pinus Pinaster Bark Extract, Polygonum Aviculare Extract, Alteromonas Ferment Extract, Padina Pavonica Thallus Extract, Arginine, Glycine, Alanine, Serine, Valine, Proline, Threonine, Isoleucine, Histidine, Phenylalanine, Aspartic Acid, PCA, Sodium PCA, Sodium Lactate, Piper Cubeba Fruit Extract, Haematococcus Pluvialis Extract, Squalane, Simmondsia Chinensis Seed Oil, Melanin, Sucrose, Lysolecithin, Tapioca Starch, Propanediol, Pentylene Glycol, Butylene Glycol, Polyglyceryl-10 Oleate, Polyglyceryl-10 Stearate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Trisodium Ethylenediamine Disuccinate, Tromethamine, Triethanolamine, Ethoxydiglycol, Tocopherol, Potassium Sorbate, Sodium Benzoate, 1,2-Hexanediol, Ethylhexylglycerin, Phenoxyethanol, Caprylyl Glycol
Cyclopentasiloxane
Dimethicone
Tetrahexyldecyl Ascorbate
Palmitoyl Tripeptide-5
Ceramide NP
Tocotrienols
Ubiquinone
Thioctic Acid
Tocopheryl Acetate
Magnesium Ascorbyl Phosphate
Ferulic Acid
Beta-Glucan
Epigallocatechin Gallate
Ergothioneine
Glutathione
Glycine Soja Seed Extract
Arctostaphylos Uva Ursi Leaf Extract
Lupinus Albus Seed Extract
Curcuma Longa Root
Elaeis Guineensis Oil
Cyclopentasiloxane, Dimethicone, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-5, Ceramide NP, Tocotrienols, Tocopherol, Ubiquinone, Thioctic Acid, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Ferulic Acid, Beta-Glucan, Superoxide Dismutase, Epigallocatechin Gallate, Ergothioneine, Glutathione, Xanthophylls, Glycine Soja Seed Extract, Glycerin, Arctostaphylos Uva Ursi Leaf Extract, Lupinus Albus Seed Extract, Curcuma Longa Root, Elaeis Guineensis Oil, Phenoxyethanol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Superoxide Dismutase is found in all living cells. This ingredient is AKA as 'SOD'.
SOD is a strong antioxidant. It protects living cells against oxidative damage by breaking down radical molecules into regular oxygen and hydrogen peroxide.
Antioxidants help fight free-radical molecules that may damage your skin's DNA. This may help with the signs of aging. Due to its antioxidant property, it is used to help treat chronic inflammation.
In cosmetics, SOD is usually obtained from marine phytoplankton, bovine liver, horseradish, cantaloupe, and certain bacteria.
The three major families of SOD include: Copper/Zinc, Iron/Manganese, and Nickel.
When eating SOD-rich foods, our bodies break it down into amino acids before absorption. Foods that contain SOD include: melons, citrus, spinach, broccoli, kale, almonds, sunflower seeds, and blue-green algae.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
We don't have a description for Xanthophylls yet.