Skin science article
Nip + Fab Hyaluronic Fix Extreme4 2% Hydration Concentrate Versus L'Oreal Revitalift Filler 1.5% Pure Hyaluronic Acid Serum
Nip + Fab Hyaluronic Fix Extreme4 2% Hydration Concentrate Versus L'Oreal Revitalift Filler 1.5% Pure Hyaluronic Acid Serum This hydrating serum is formulated around Sodium Hyaluronate and Tremella Fuciformis Sporocarp Extract to hydrate skin and strengthen th
Nip + Fab Hyaluronic Fix Extreme4 2% Hydration Concentrate Versus L'Oreal Revitalift Filler 1.5% Pure Hyaluronic Acid Serum
This hydrating serum is formulated around Sodium Hyaluronate and Tremella Fuciformis Sporocarp Extract to hydrate skin and strengthen the skin barrier.
This anti-aging serum is formulated around Sodium Hyaluronate and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Butylene Glycol
Sodium Hyaluronate
Tremella Fuciformis Sporocarp Extract
Sodium Polyglutamate
Panthenol
Phenoxyethanol
Benzyl Alcohol
Xanthan Gum
Ethylhexylglycerin
Dehydroacetic Acid
Sodium Hydroxide
Water, Glycerin, Butylene Glycol, Sodium Hyaluronate, Tremella Fuciformis Sporocarp Extract, Sodium Polyglutamate, Panthenol, Phenoxyethanol, Benzyl Alcohol, Xanthan Gum, Ethylhexylglycerin, Dehydroacetic Acid, Sodium Hydroxide
Hydroxyethylpiperazine Ethane Sulfonic Acid
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Disodium EDTA
Secale Cereale Seed Extract
Ascorbyl Glucoside
Calcium Pantothenate
PEG-60 Hydrogenated Castor Oil
Pentylene Glycol
Benzyl Benzoate
Benzyl Salicylate
Citronellol
Linalool
Chlorphenesin
Parfum
Water, Glycerin, Hydroxyethylpiperazine Ethane Sulfonic Acid, Sodium Hyaluronate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Disodium EDTA, Secale Cereale Seed Extract, Ascorbyl Glucoside, Calcium Pantothenate, PEG-60 Hydrogenated Castor Oil, Pentylene Glycol, Benzyl Alcohol, Benzyl Benzoate, Benzyl Salicylate, Citronellol, Linalool, Chlorphenesin, Phenoxyethanol, Parfum
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Benzyl Alcohol is an aromatic alcohol with several roles: it's a preservative, solvent, and mild fragrance component with a floral scent.
This ingredient has been deemed safe for use in cosmetic formulations at concentrations up to 5%, and up to 10% in hair dyes. You'll typically see 0.5-2% in most rinse-off or leave-on products.
As a preservative, it works by disrupting the membrane of microbial proteins. This helps keep bacteria and fungi from growing in your products.
The sensitization picture is actually quite assuring as well:of nearly 71,000 patients patch tested with benzyl alcohol, only 0.21% showed a positive reaction with most of them being weakly positive.
This led researchers to conclude that benzyl alcohol cannot be regarded as a significant contact allergen.
It is worth noting this ingredient is classified as one of the EU's regulated fragrance allergens and restricted to 1% in finished products.
Labels must also declare it in concentrations above 0.001% in leave-on products and 0.01% in rinse-off products.
At concentrations around 5%, localized redness and itching can appear as a direct irritant response and not as a true allergic reaction.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!