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Skin science article

Novology Pigmentation Reduction Bi-Phasic Serum Versus Paula's Choice Resist Triple Active Total Repair Serum

Novology Pigmentation Reduction Bi-Phasic Serum Versus Paula's Choice Resist Triple Active Total Repair Serum This brightening serum is formulated around Niacinamide and Hexylresorcinol to fade the look of dark spots and brighten dull-looking skin. This anti-a

Novology Pigmentation Reduction Bi-Phasic Serum Versus Paula's Choice Resist Triple Active Total Repair Serum

This brightening serum is formulated around Niacinamide and Hexylresorcinol to fade the look of dark spots and brighten dull-looking skin.

This anti-aging serum is formulated around Niacinamide and Retinyl Propionate to soften the look of wrinkles and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Isodecyl Neopentanoate

Glycerin

Caprylic/Capric Triglyceride

Niacinamide

Caprylyl/Capryl Glucoside

Tocopheryl Acetate

Phenoxyethanol

Sodium Chloride

Hexylresorcinol

Retinyl Propionate

Cocamide Mea

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Propylene Glycol

Iodopropynyl Butylcarbamate

Helianthus Annuus Seed Oil

Parfum

Benzyl Alcohol

Citronellol

Linalool

CI 42090

CI 17200

CI 19140

CI 40800

Water, Isodecyl Neopentanoate, Glycerin, Caprylic/Capric Triglyceride, Niacinamide, Caprylyl/Capryl Glucoside, Tocopheryl Acetate, Phenoxyethanol, Sodium Chloride, Hexylresorcinol, Retinyl Propionate, Cocamide Mea, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Propylene Glycol, Iodopropynyl Butylcarbamate, Helianthus Annuus Seed Oil, Parfum, Benzyl Alcohol, Citronellol, Linalool, CI 42090, CI 17200, CI 19140, CI 40800

Isopropyl Myristate

Hydroxystearic Acid

Oryza Sativa Bran Oil

Tocotrienols

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Cetyl Alcohol

Castanea Sativa Leaf Extract

Hydroxyacetophenone

Ceramide AP

1,2-Hexanediol

Caprylyl Glycol

Sodium Hydroxide

Dilauryl Thiodipropionate

Sodium Phytate

BHT

Water, Isopropyl Myristate, Caprylic/Capric Triglyceride, Glycerin, Niacinamide, Hydroxystearic Acid, Oryza Sativa Bran Oil, Tocotrienols, Retinyl Propionate, Hexylresorcinol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetyl Alcohol, Castanea Sativa Leaf Extract, Hydroxyacetophenone, Ceramide AP, 1,2-Hexanediol, Caprylyl Glycol, Sodium Hydroxide, Dilauryl Thiodipropionate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Phytate, BHT

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Another popular name for this ingredient is Synovea HR. This ingredient is a skin lightener and antioxidant.

Like other skin lighteners, it blocks the process of skin darkening. Specifically, this ingredient blocks tyrosinase, the enzyme responsible for darkening skin when exposed to UV.

Hexylresorcinol works well with other ingredients. Studies show this ingredient boosts the effect of niacinamide, various forms of vitamin C, and retinoids.

Many consider this to be a safer alternative to hydroquinone. In fact, this ingredient produces the same results as hydroquinone in lower amounts.

Fun fact: This ingredient can also be found food and medicine for treating skin infections.

Gentle reminder from SkinSort: all skin tones are beautiful!

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.

It is used to help stabilize other antioxidants or prevent the color from changing in a product.

As an antioxidant, it helps fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Thus, antioxidants may reduce the signs of aging.

This ingredient is oil-soluble.

Retinyl Propionate is a retinoid. Retinoids are the gold-standard class of anti-aging ingredients.

Most retinoids have to be converted to become effective. For some, this conversion line is long and possible ineffective. The end goal? Retinoid acid, AKA tretinoin.

Retinyl Propionate is an ester of retinol, like Retinyl Palmitate. Though the conversion line is longer for this ingredient - the results seem promising.

A study from 2021 found Retinyl Propionate to be just as effective as retinol . FYI - Retinol is one of the most well-studied OTC ingredients.

Other studies show promising results as well:

Reducing sun damage helps with: reducing the appearance of wrinkles, evening out skin tone, increasing skin plumpness, and decreasing dullness.

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Simmondsia Chinensis Seed Oil
  3. 03Butyrospermum Parkii Butter
  4. 04Isododecane
  5. 05Coconut Alkanes
  6. 063-O-Ethyl Ascorbic Acid
  7. 07Cetearyl Alcohol
  8. 08Glycerin
  9. 09C18-38 Alkyl Hydroxystearoyl Stearate
  10. 10Dilinoleic Acid/Propanediol Copolymer
  11. 11Polymethylsilsesquioxane
  12. 12Cocoyl Proline
  13. 13Dimethicone Crosspolymer
  14. 14Pentaerythrityl Tetraisostearate
  15. 15Tetrahexyldecyl Ascorbate
  16. 16Ascorbic Acid
  17. 17Gold
  18. 18Glutathione
  19. 19Citrus Nobilis Fruit Extract
  20. 20Citrus Paradisi Peel Extract
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side